Chemical composition, toxicity and mosquito repellency of Ocimum selloi oil

Paula, Josiane Padilha de; Gomes-Carneiro, Maria Regina; Paumgartten, Francisco José Roma

doi:10.1016/s0378-8741(03)00233-2

Cited by 74 publications

(23 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results are in agreement with the results previously shown by other authors using different assays, which demonstrated the absence of the genotoxicity of a great number of essential oils and stated out that only few essential oils are genotoxic [10] [12] [27]- [32]. But it must be noted that the positive results demonstrating the genotoxic effect of many essential oils were also found [9].…”

Section: Discussionsupporting

confidence: 93%

“…A positive effect was also detected in the Bacillus subtilis DNA-repair test (Rec-assay) with cinnamaldehyde and with methyl chavicol [27]. 1,8-Cineole, an important molecule found in Laurel oil and even more present in Rosemary essential oil, did not show any mutagenic effect by the Salmonella assay [32]. Thymol was screened for mutagenic activity using the same test; no effect was detected with this important savory oil compound [34].…”

Section: Discussionmentioning

confidence: 98%

“…Also, no evidence of myrcene-induced clastogenicity was observed using the rat bone marrow cytogenetic in vivo assay [40] and no mutagenic effect in Salmonella typhimurium with borneol was detected [34]. However, the Terpineol present in many essential oils tested caused a slight but dose-related increase in the number of his + revertants with TA102 Salmonella tester strain both without and with addition of S9 mixture [32]. For their part, methyl eugenol and eugenol did not show mutagenicity in the Ames assay and in the Escherichia coli WP2 uvrA reversion test [27] [34].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Genotoxicity of Some Essential Oils Frequently Used in Aromatherapy

Mezzoug¹,

Idaomar²,

Baudoux³

et al. 2016

ABB

View full text Add to dashboard Cite

Genotoxic properties of the essential oils extracted from Artemisia dracunculus (tarragon), Ocimum basilicum (basil), Cinnamomum loureirii (cinnamon), Laurus nobilis (laurel), Satureja montana (savory) and Rosmarinus officinallis (rosemary) are studied by Drosophila melanogaster Somatic Mutation and Recombination Test (SMART). The high bioactivation crossed with a high cytochrome P450-dependent bioactivation capacity is used. This assay is principally based on the loss of heterozygosity of the suitable recessive markers' multiple wing hairs (mwh) and flare-3 (flr 3 ) which can lead to the formation of mutant clones of larval cells, and which are then going to be expressed as spots on the wings of adult flies. Third-instar larvae are treated for 48 hr with different concentrations of the essential oils dissolved in Tween-80 at 0.2% or 2%. The wings of the emerging adults are analyzed for the occurrence of different types of mutant spots. No statistically significant differences in spot frequencies between negative controls and treated series are observed. These results suggest that the six essential oils at concentrations tested are not genotoxic towards somatic cells of D. melanogaster.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Genotoxicity of Some Essential Oils Frequently Used in Aromatherapy

Mezzoug¹,

Idaomar²,

Baudoux³

et al. 2016

ABB

View full text Add to dashboard Cite

show abstract

“…Good examples are the larvicidal EOs obtained from Clausena anisata (Govindarajan 2010b), Coleus aromaticus (Govindarajan et al 2013b), Dalbergia sisoo (Ansari et al 2000a), Hyptis martiusii (Araujo et al 2003), Hyptis suaveolens (Sakthivadivel et al 2015), Lavandula gibsoni (Kulkarni et al 2013), Lippia sidoides (Lima et al 2013), Moschosma polystachyum (Rajkumar and Jebanesan 2004), Mentha spicata (Govindarajan et al 2012), Mentha piperita (Ansari et al 2000b), Mentha longifolia (Pavela et al 2014), Ocimum basilicum (Govindarajan et al 2013a), Ocimum selloi (Padilha de Paula et al 2003), Ocimum americanum (Tawatsin et al 2001), Ocimum gratissimum (Cavalcanti et al 2004), Ocimum sanctum (Gbolade and Lockwood 2008), Plectranthus barbatus ), Plectranthus ambonicus (Lima et al 2011), Plectranthus mollis (Kulkarni et al 2013), Pogostemon cablin (Trongtokit et al 2005), Pulegium vulgare (Pavela et al 2014), Rosmarinus officinalis (Prajapati et al 2005), Satureja hortensis (Pavela 2009), Tagetus minuta (Perich et al 1995), Thymus vulgaris (El-Akhal et al 2016), Thymus leucospermus, Thymus teucrioides (Pitarokili et al 2011), Vitex agnus castus (Cetin et al 2011), and others (Cheng et al 2003;Traboulsi et al 2005;Pavela et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Acute toxicity and repellent activity of the Origanum scabrum Boiss. & Heldr. (Lamiaceae) essential oil against four mosquito vectors of public health importance and its biosafety on non-target aquatic organisms

Govindarajan

Kadaikunnan

Alharbi

et al. 2016

Environ Sci Pollut Res

View full text Add to dashboard Cite

The recent outbreaks of dengue, chikungunya, and Zika virus highlighted the pivotal importance of mosquito vector control in tropical and subtropical areas worldwide. However, mosquito control is facing hot challenges, mainly due to the rapid development of pesticide resistance in Culicidae and the limited success of biocontrol programs on Aedes mosquitoes. In this framework, screening botanicals for their mosquitocidal potential may offer effective and ecofriendly tools in the fight against mosquitoes. In the present study, the essential oil (EO) obtained from the medicinal plant Origanum scabrum was analyzed by GC-MS and evaluated for its mosquitocidal and repellent activities towards Anopheles stephensi, Aedes aegypti, Culex quinquefasciatus, and Culex tritaeniorhynchus. GC-MS analysis showed a total of 28 compounds, representing 97.1 % of the EO. The major constituents were carvacrol (48.2 %) and thymol (16.6 %). The EO was toxic effect to the A. stephensi, A. aegypti, C. quinquefasciatus, and C. tritaeniorhynchus larvae, with LC 50 of 61.65, 67.13, 72.45, and 78.87 μg/ml, respectively.Complete ovicidal activity was observed at 160, 200, 240, and 280 μg/ml, respectively. Against adult mosquitoes, LD 50 were 122.38, 134.39, 144.53, and 158.87 μg/ml, respectively. In repellency assays, the EOs tested at 1.0, 2.5, and 5.0 mg/cm 2 concentration of O. scabrum gave 100 % protection from mosquito bites up to 210, 180, 150, and 120 min, respectively. From an eco-toxicological point of view, the EO was tested on three non-target mosquito predators, Gambusia affinis, Diplonychus indicus, and Anisops bouvieri, with LC 50 ranging from 4162 to 12,425 μg/ml. Overall, the EO from O. scabrum may be considered as a low-cost and eco-friendly source of phytochemicals to develop novel repellents against Culicidae.

show abstract

“…(E)-anethole is highly effective as a fumigant against the cockroach Blattella germanica. Anethole is an effective insect repellent against mosquitos (6).…”

Section: Antioxidant Activitymentioning

confidence: 99%

Review on the pharmacological activities of anethole

Marinov

Valcheva-Kuzmanova

2015

Scripta Scientifica Pharmaceutica

View full text Add to dashboard Cite

The chemical structure of anethole is given in Fig. 1. Anethole exists as both cis and trans isomers, involving the double bond outside the ring. The more abundant isomer, and the one preferred for use, is the trans or E isomer.Anethole is clear, colorless to amber liquid with a sweet anise-like flavor. Anethole is only slightly soluble in water but exhibits high solubility in ethanol. This difference causes certain anise-flavored liqueurs to become opaque when diluted with water. This is due to the spontaneous formation of a microemulsion.Anethole is distinctly sweet, 13 times sweeter than sugar. It is used in many alcoholic drinks. It flavors Middle Eastern arak, Colombian aguardiente, French spirits absinthe, anisette and pastis, Greek ouzo, Bulgarian and Macedonian mastika, German Jägermeister, Italian sambuca, Dutch Brokmöpke, Portuguese, Peruvian, and Spanish anísado, Herbs de Majorca, Mexican Xtabentún and Turkish rakı.Anethole can cover unpleasant odours, so it is widely used as a masking agent in commodities, such as toilet soap, toothpaste, mouthwash, etc. This is the main use of anethole, about 80% of the total. It is used as a flavouring additive and scent in food industry products such as candy, baked goods, chewing gum, cigarettes, etc. ABSTRACTIn recent years there has been an increasing interest in the activities of phytopharmaceutical products and biologically active substances of plant origin. Anethole is such a substance used from ancient times in traditional medicine in many countries. Nowadays it is widely used in food and beverage industry. Its widespread use and accessible price justify carrying out extensive scientific research in order to support the traditional uses of anethole with scientific evidence. This review article summarizes the current knowledge of the traditional use of anethole, its pharmacological activities and the possible mechanisms underlying its effects.

show abstract

Chemical composition, toxicity and mosquito repellency of Ocimum selloi oil

Cited by 74 publications

References 17 publications

Genotoxicity of Some Essential Oils Frequently Used in Aromatherapy

Genotoxicity of Some Essential Oils Frequently Used in Aromatherapy

Acute toxicity and repellent activity of the Origanum scabrum Boiss. & Heldr. (Lamiaceae) essential oil against four mosquito vectors of public health importance and its biosafety on non-target aquatic organisms

Review on the pharmacological activities of anethole

Contact Info

Product

Resources

About