Chemical Composition and Evaluation of the Biological Properties of the Essential Oil of the Dietary Phytochemical Lippia citriodora

Fitsiou, Eleni; Mitropoulou, Gregoria; Spyridopoulou, Katerina; Vamvakias, Manolis; Bardouki, Haido; Galanis, Αlex; Chlichlia, Katerina; Kourkoutas, Yiannis; Panayiotidis, Mihalis Ι.; Pappa, Aglaia

doi:10.3390/molecules23010123

Cited by 37 publications

(33 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Geranial, nerol and benzenamine were not detected in the present study but the others with different values were recognized. Fitsiou et al (2018) revealed that geranial (26.4%), neral (17.2%), nerol (8.0%), geraniol (5.7%), spathulenol (3.3%), 1.8cineol (3.2%) and limonene (2.2%) had high amount in the essential oil of L. citriodora from Greece. Geranial, geraniol and nerol were not found in the essential oil of present study while neral, spathulenol and 1.8-cineol with different percentages were detected in both tested oils.…”

Section: Resultsmentioning

confidence: 99%

“…Lemon verbena [Lippia citriodora Kunth (Verbenaceae)], is one of the most cultivated medicinal plants, which used in the preparation of herbal tea for its lemon-like aroma (Argyropouloua et al, 2007, Kizil et al, 2018. Along with diuretic, antipyretic, antispasmodic, and sedative properties, the antimicrobial and antioxidant effects of this GRAS (Generally Regarded As Safe) listed plant was also demonstrated (Gomes et al, 2006, Farahmandfar et al, 2018, Fitsiou et al, 2018. Therefore, the aim of present study was to describe the chemical profile of two Iranian L. citriodora essential oils and assess their fumigant toxicity against R. dominica and T. castaneum.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chemical Composition and Toxicity of the Essential Oils of Lippia Citriodora From Two Different Locations Against Rhyzopertha Dominica and Tribolium Castaneum

Ebadollahi¹,

Razmjou²

2019

AgricultForest

View full text Add to dashboard Cite

The lesser grain borer, Rhyzopertha dominica (F.), and the red flour beetle, Tribolium castaneum (Herbst), are among broad-based damaging insect pests of agricultural stored products. Because of several side-effects of conventional chemical insecticides to the human health, non-target organisms, and environment, searching for and introducing healthy, inexpensive, accessible and efficient agents is necessary. In the present study, chemical profiles and fumigant toxicity of the essential oils isolated from L. citriodora against R. dominica and T. castaneum were evaluated. Chemical compositions of L. citriodora essential oils from two different Iranian regions including Germi and Parsabad was evaluated by gas chromatography-mass spectrometry (GC-MS) and it was found that the terpenic compounds such as caryophyllene oxide, citral, limonene, and neral has the high amount in both oil. Some components such as sabinene, sulcatone, and β-ocimene were only identified in the essential oil from Germi region while some others such as verbenone, camphor, borneol with considerable amount in Parsabad region had not any trace in Germi' origin essential oil. The results of bioassays showed that the essential oils of L. citriodora from both regions had significant fumigant toxicity against the adults of R. dominica and T. castaneum. In general, essential oils' concentrations and exposure times had direct positive effects on the observed mortality. According to the results of present study, the terpene rich L. citriodora essential oils from two Iranian regions (Germi and Parsabad) have a high potential for the management of R. dominica and T. castaneum.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Toxicity of the Essential Oils of Lippia Citriodora From Two Different Locations Against Rhyzopertha Dominica and Tribolium Castaneum

Ebadollahi¹,

Razmjou²

2019

AgricultForest

View full text Add to dashboard Cite

show abstract

“…Single cell gel electrophoresis (comet) assay was performed as described previously [ 28 , 29 ]. Briefly, HaCaT cells (2 × 10 4 ) were treated with S. raeseri subsp.…”

Section: Methodsmentioning

confidence: 99%

Assessment of the Antimicrobial, Antioxidant, and Antiproliferative Potential of Sideritis raeseri subps. raeseri Essential Oil

Mitropoulou

Sidira²,

Skitsa

et al. 2020

Foods

Self Cite

View full text Add to dashboard Cite

The aim of the present study was to investigate the antimicrobial potential of Sideritis raeseri subps. raeseri essential oil (EO) against common food spoilage and pathogenic microorganisms and evaluate its antioxidant and antiproliferative activity. The EO was isolated by steam distillation and analyzed by GC/MS. The main constituents identified were geranyl-p-cymene (25.08%), geranyl-γ-terpinene (15.17%), and geranyl-linalool (14.04%). Initially, its activity against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Listeria monocytogenes, Salmonella Enteritidis, Salmonella Typhimurium, Pseudomonas fragi, Saccharomyces cerevisiae, and Aspergillus niger was screened by the disk diffusion method. Subsequently, minimum inhibitory concentration (MIC), non-inhibitory concentration (NIC), and minimum lethal concentration (MLC) values were determined. Growth inhibition of all microorganisms tested was documented, although it was significantly lower compared to gentamycin, ciproxin, and voriconazole, which were used as positive controls. In a next step, its direct antioxidant properties were examined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays, and the IC50 values were determined. The potential cytoprotective activity of the oil against H2O2–induced oxidative stress and DNA damage was studied in human immortalized keratinocyte (HaCaT) cells using the comet assay. Finally, the antiproliferative activity of the oil was evaluated against a panel of cancer cell lines including A375, Caco2, PC3, and DU145 and the non-cancerous HaCaT cell line using the sulforhodamine B (SRB) assay, and the EC50 values were determined. The oil demonstrated weak radical scavenging activity, noteworthy cytoprotective activity against H2O2–induced oxidative stress and DNA damage in HaCaT cells, and antiproliferative activity against all cell lines tested, being more sensitive against the in vitro model of skin melanoma.

show abstract

“…Briefly, a solution of DPPH in ethanol was prepared and this solution (100.0 μL) was added to 100.0 μL of essential oil solutions at different concentrations. The mixture was shaken and left to stand for 30 min in the dark at room temperature, and then we measured the absorbance at 517 nm [ 47 ].…”

Section: Methodsmentioning

confidence: 99%

The Chemical Composition and Functional Properties of Essential Oils from Four Species of Schisandra Growing Wild in the Qinling Mountains, China

et al. 2018

View full text Add to dashboard Cite

The aim of this study was to investigate the chemical composition and functional properties of the essential oils from the plants Schisandra grandiflora (Wall.) Hook. f. et Thoms, Schisandra rubriflora (Franch). Rehd. et Wils., Schisandra sphenanthera Rehd. et Wils., and Schisandra propinqua (Wall.) Baill var. sinensis Oliv. collected in the Qinling Mountains. Under the optimum conditions of the ultrasonic-assisted extraction method, the extraction yields were 7.51% (S. grandiflora), 6.91% (S. rubriflora), 6.11% (S. sphenanthera), and 5.88% (S. propinqua). A total of 86 components were identified from four species of Schisandra and 16 components were shared among the essential oils of all samples with different contents. However, some components were identified only in a certain plant, for example, β-caryophyllen (S. grandiflora), α-bulnesene (S. rubriflora), and α-Chamigrene (S. propinqua). Terpenoids (sesquiterpenes and oxygenated sesquiterpenes), accounting for 73.87–82.08% of the total compounds, were the main components. Meanwhile, the antioxidant activities of the essential oils were evaluated through three free radical scavenging assays and a reducing power assay, which were related to the contents of the individual bioactive composition. These results provide a phytochemical foundation for the use of four species, and for the further study of the identification of Schisandra species.

show abstract

Chemical Composition and Evaluation of the Biological Properties of the Essential Oil of the Dietary Phytochemical Lippia citriodora

Cited by 37 publications

References 35 publications

Chemical Composition and Toxicity of the Essential Oils of Lippia Citriodora From Two Different Locations Against Rhyzopertha Dominica and Tribolium Castaneum

Chemical Composition and Toxicity of the Essential Oils of Lippia Citriodora From Two Different Locations Against Rhyzopertha Dominica and Tribolium Castaneum

Assessment of the Antimicrobial, Antioxidant, and Antiproliferative Potential of Sideritis raeseri subps. raeseri Essential Oil

The Chemical Composition and Functional Properties of Essential Oils from Four Species of Schisandra Growing Wild in the Qinling Mountains, China

Contact Info

Product

Resources

About