Chemical Composition and Cosmeceutical Potential of the Essential Oil of Oncosiphon suffruticosum (L.) Källersjö

Abstract

The South African medicinal plant Oncosiphon suffruticosum (L.) Källersjö is an important remedy used to treat chronic, respiratory, and skin ailments. From the essential oil (EO) extracted by the hydrodistillation, sixteen constituent components were identified with oxygenated monoterpenes: camphor (31.21%), filifolone (13.98%), chrysanthenone (8.72%), 1,8-cineole (7.85%), and terpinen-4-ol (7.39%) as predominant constituents. In the antibacterial activity study, the EO was found most susceptible against Pseudomonas aeruginosa with an MIC of 6.4 mg/mL; however, it showed the same activity against Staphylococcus aureus and Escherichia coli with an MIC value of 12.8 mg/mL. The sun protecting factor (SPF) of the EO was found to be 2.299 and thus establishing it as a potentially important cosmeceutical for sunscreen applications. This is the first report investigating the essential oil of O. suffruticosum for its chemical composition and skin-related in vitro biological activities viz antibacterial, antioxidant capacity, antityrosinase, and sun protection factor.

Photoprotective Agents Obtained from Aromatic Plants Grown in Colombia: Total Phenolic Content, Antioxidant Activity, and Assessment of Cytotoxic Potential in Cancer Cell Lines of Cymbopogon flexuosus L. and Tagetes lucida Cav. Essential Oils

“…In this work, the cosmeceutical potential of twelve EOs obtained from plants grown in Colombia was determined by in vitro assessment of broad-spectrum UV-protection indices [39]. In addition, the total phenolic content was analyzed [25]. Based on the UV-protection indices, the two EOs with the best results were selected, and their cytotoxic activity was determined using cell lines of human hepatocellular carcinoma (HepG2) and lung squamous cell carcinoma (Calu-1), as well as their cytoprotective effects against oxidative stress induced by H 2 O 2 .…”

“…The antioxidant activity is a fundamental mechanism of the photoprotective activity of EOs and the extract of plants [25]. Skin damage by UV radiation depends on the generation of ROS, which includes peroxyl radicals (ROO•), hydroxyl radicals (OH•), and superoxide anions (O 2 •) [60].…”

“…In this regard, SPF values in EOs of 8.36 and 14.84 have been reported for Calendula officinalis [30,68], SPF of 6.282 for Cymbopogon spp. [39], an SPF of 2.299 for Oncosiphon suffruticosum [25] and an SPF of 6.45 for the Pelargonium graveolens EO [30]. The calculation of the photoprotection indices identified for the C. citratus, L. alba, and L. origanoides (Carvacrol/thymol chemotype) EOs indicated that they are promising candidates as broad-spectrum UVA and UVB sunscreens, with λc values of 360.9, 346.7, and 351.4 nm, respectively.…”

“…As photoprotective agents, these molecules have broad-spectrum UV absorption that includes regions between 290 nm and 400 nm. UV radiation is a dangerous environmental agent that causes molecular alterations and several harmful responses in skin cells [21][22][23][24][25]. This radiation range downregulates ROS elimination pathways, thereby promoting their production in mitochondria-mediated apoptosis [17].…”

GC-MS Chemical profile, Antioxidant Activity, and Sun Protection Factor of Essential Oil of Tea Tree (Melaleuca alternifolia) and Rosemary (Rosmarinus officinalis L.)

“…The Mansur equation was then used to calculate the sun protection factor values for the formulations. The In vitro method is replaced by a combination of two relatively simple mathematical equations 24…”