Chemical composition and biological activity of Citrus jambhiri Lush

Hamdan, Dalia I.; El-Readi, Mahmoud Zaki; Tahrani, Ahmad; Herrmann, Florian; Kaufmann, Dorothea; Farrag, Nawal; El-Shazly, Assem M.; Wink, Michael

doi:10.1016/j.foodchem.2010.12.129

Cited by 102 publications

(57 citation statements)

References 25 publications

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“…): m/z 388, which in accordance with molecular formula C 20 H 20 O 8 . It appeared as a dark purple spot under UV light and with on spraying with anisaldehyde/sulfuric acid reagent and heating in an oven at 110°C for 5 min, it yield yellow spot and its spectral analyses were in accordance with previously published data of 5-O-demethylnobiletin (Hamdan et al, 2011). 62.16, 61.80, 61.24, 56.00 (4 s, four methoxy groups at C-6, 7, 8, 3').…”

Section: Identification Of the Isolated Compoundssupporting

confidence: 87%

Anticancer, Anti HIV-1 and Antimicrobial Potentials of Methanol Extract and Non Polar Fractions of Citrus volkameriana Leaves and Phytochemical Composition

Said¹,

El-fiky²,

Rashed³

et al. 2015

Research J. of Medicinal Plant

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This study investigated anticancer, anti HIV-1, antimicrobial potentials and the phytochemical composition of the total methanol extract, petroleum ether (60-80°C) and dichloromethane fractions of Citrus volkameriana leaves. Anticancer activity was measured by a sulforhodamine B (SRB) assay. Syncytia formation assay was used to evaluate anti-HIV-1 potential and antimicrobial assay was performed according to Buwa and Van staden with some modifications. The results showed that petroleum ether fraction exerted growth inhibitory effect on melanoma cancer cell line (UACC62), it inhibited the syncytia formation of HIV-1 with EC 50 of 17.4 µg mLG

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Section: Identification Of the Isolated Compoundssupporting

confidence: 87%

Anticancer, Anti HIV-1 and Antimicrobial Potentials of Methanol Extract and Non Polar Fractions of Citrus volkameriana Leaves and Phytochemical Composition

Said¹,

El-fiky²,

Rashed³

et al. 2015

Research J. of Medicinal Plant

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“…In the context of our chemical and biological investigation of Citrus species cultivated in Egypt Hamdan et al, 2010Hamdan et al, , 2011a, essential oils from the fruit peel and leaves of variegated pink-fl eshed lemon were analysed by high-resolution capillary GLC and GLC-MS (gas-liquid chromatography-mass spectroscopy). In order to understand their biological properties, antioxidant, anti-infl ammatory, antitrypanosomal, and antimicrobial activities were assessed.…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition of the Essential Oils of Variegated Pink-Fleshed Lemon (Citrus x limon L. Burm. f.) and their Anti-Inflammatory and Antimicrobial Activities

Hamdan

Ashour

Mulyaningsih

et al. 2013

Zeitschrift Für Naturforschung C

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The volatile secondary metabolites of essential oils from fruit peel and leaves of variegated pink-fl eshed lemon (Citrus x limon) were investigated using GLC and GLC-MS (gas-liquid chromatography-mass spectroscopy). Altogether 141 compounds were identifi ed and quantifi ed, accounting for 99.59% and 96.33% of the total hydrodistilled peel and leaf oil, respectively. Limonene occurred in higher amounts in fruit peel (52.73%) than in leaf oil (29.13%). Neral (12.72%), neryl acetate (8.53%), ρ-menth-1-en-7-al (4.63%), β-pinene (6.35%), and nerol (4.42%) were the most abundant constituents in leaf oil, whereas γ-terpinene (9.88%), β-pinene (7.67%), geranial (4.44%), and neral (3.64%) dominated in the fruit peel oil. The antioxidant, anti-infl ammatory, antitrypanosomal, and antimicrobial activities of the fruit peel essential oil were evaluated. The oil had a low antioxidant activity with an IC 50 value of (26.66 ± 2.07) mg/ml as compared to the effi cient antioxidant ascorbic acid [IC 50 (16.32 ± 0.16) μg/ml]. The oil moderately inhibited soybean 5-lipoxygenase (5-LOX) with an IC 50 value of (32.05 ± 3.91) μg/ml and had moderate antitrypanosomal activity [IC 50 (60.90 ± 0.91) μg/ml]. In addition, moderate antimicrobial activities were detected against Gram-positive bacteria (Bacillus subtilis, Staphylococcus capitis, Micrococcus luteus), one Gram-negative bacterium (Pseudomonas fl uorescens), and yeasts (Saccharomyces cerevisiae, Candida parapsilosis).

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“…Numerous studies have been performed on the chemical composition, antimicrobial, antifungal, antioxidant and radical scavenging abilities of the essential oils of peel and leaf of various species and/or cultivars of lemon around the world, where limonene has been always the prominent component found in all peel essential oils, whereas the leaf essential oil was generally rich in limonene, in some case other compounds were the major constituents (5,6,(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22).…”

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confidence: 99%

Chemical Composition and Biological Activities of Lemon (Citrus limon) Leaf Essential Oil

Hojjati

Barakat

2017

Nutr Food Sci Res

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A B S T R A C TBackground and Objectives: Essential oils and their compounds are getting increasing interest due to their multipurpose functionals as alternatives to the artificial preservatives. The aim of this study was to extract and identify the volatile constituents of essential oil of Citrus lemon leaf and to evaluate its antioxidant and antibacterial abilities. Materials and Methods:The essential oil was extracted using Clevenger apparatus and characterized by means of gas chromatography mass spectrometry (GC-MS). Folin-Ciocalteu method was used to determine the total phenolic equivalent (TPC). The antioxidant properties of the essential oil were evaluated by 2,2-diphenylpicrylhydrazyl (DPPH) assay and the detection of inhibitory effect of the essential oil at various concentrations (0.025-10 mg/mL) on Staphylococcus aureus, Bacillus cereus, Streptococcus faecium, Escherichia coli, Salmonella typhi and Shigella dysentery was carried out by agar disc-diffusion method and then Minimum Inhibitory Concentration (MIC) assay was evaluated.Results: GC-MS analysis allowed the identification of twenty-seven compounds and linalool (30.62%), geraniol (15.91%), α-terpineol (14.52%), and linalyl acetate (13.76%) were the main constituents. TPC of essential oil was 14.73 mg gallic acid equivalent/g dry plant material and its IC 50 value was found to be 0.98 mg/mL in DPPH test, so lemon leaf essential oil showed good free radical scavenging capacity at all studied concentrations. However the antioxidant capacity increased with increasing concentration of the essential oil. The results showed that increasing the essential oil concentration, increases the zone of inhibition, so that the highest antibacterial activity was observed at 10 mg/mL of essential oil. The results of antimicrobial activity by disc diffusion method showed that essential oil exhibited maximum zone inhibition against Gram-positive bacteria including B. cereus, S. aureus and S. faecium, whereas the minimum zone inhibition was shown by S. typhi and S. dysentery as Gram-negative pathogens at the same concentrations. The highest MIC showed by S. aureus and S. dysentery, whereas the least MIC value was observed with B. cereus and S. typhi. Conclusions:The results obtained in this study have shown the moderate biological potential of essential oil of C. limon leaf is probably due to its particular chemical composition, mainly the high amounts of linalool. Therefore, this essential oil could be used to raise the shelf life of foods as a natural preservative ingredient.

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Chemical composition and biological activity of Citrus jambhiri Lush

Cited by 102 publications

References 25 publications

Anticancer, Anti HIV-1 and Antimicrobial Potentials of Methanol Extract and Non Polar Fractions of Citrus volkameriana Leaves and Phytochemical Composition

Anticancer, Anti HIV-1 and Antimicrobial Potentials of Methanol Extract and Non Polar Fractions of Citrus volkameriana Leaves and Phytochemical Composition

Chemical Composition of the Essential Oils of Variegated Pink-Fleshed Lemon (Citrus x limon L. Burm. f.) and their Anti-Inflammatory and Antimicrobial Activities

Chemical Composition and Biological Activities of Lemon (Citrus limon) Leaf Essential Oil

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