Chemical composition and biological activity of the essential oil of <i>Ballota hispanica</i> (L.) Benth. growing wild in Sicily

Riccobono, Luana; Jemia, Mariem Ben; Senatore, Felice; Bruno, Maurizio

doi:10.1080/11263504.2014.1001462

Cited by 7 publications

(5 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…uncinata and subsp. foetida , B. undulata and B. saxatilis (Fraternale et al 2009; Fraternale & Ricci 2014; Riccobono et al 2016; Rigano et al 2017, 2020). Despite the detailed technical approaches used in this study, the volatile profile provided suggests the need for further studies on B. acetabulosa volatile profile using in vivo techniques.…”

Section: Discussionmentioning

confidence: 99%

“…uncinata and subsp. foetida , B. undulata , B. saxatilis and B. hispanica , some of which refer to Italian samples (Riccobono et al 2016; Rigano et al 2017, 2020; El Mokni et al 2020). With regard to B. acetabulosa , the literature offers several studies on the characterization of extracts of increasing polarity in relation to their potential biological activity; moreover, there are studies in which the composition of polyphenolic, flavonoidic and diterpenic content are analysed (Sahpaz et al 2002; Couladis et al 2003; Yilmaz & Çitoǧlu 2003; Dumlu & Bulut 2007; Dulger & Kilcik 2011a, 2011b; Dulger & Dulger 2012; Askun et al 2013; Rosselli et al 2019).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Micromorphological and phytochemical survey of Ballota acetabulosa (L.) Benth

et al. 2021

View full text Add to dashboard Cite

Within the Open Science project entitled ‘Botanic Garden, factory of molecules’, a multidisciplinary study approach was applied to Ballota acetabulosa (L.) Benth., at the Ghirardi Botanic Garden (Toscolano Maderno, BS, Italy). Micromorphological and histochemical investigations were performed on the secreting structures of the vegetative and reproductive organs under light, fuorescence and electronic microscopy. Concurrently the characterization of the volatiles spontaneously emitted from leaves and flowers were examined. Four trichome morphotypes were identified: peltate and short‐stalked, medium‐stalked and long‐stalked capitate trichomes, each with a specific distribution pattern. The histochemical analysis was confirmed using ultrastructural observations, with the peltates and long‐stalked capitates as the main sites responsible for terpene production. The head‐space characterization revealed that sesquiterpene hydrocarbons dominated both in leaves and flowers, with γ‐muurolene, β‐caryophyllene and (E)‐nerolidol as the most abundant compounds. Moreover, a comparison with literature data concerning the ecological roles of the main compounds suggested their dominant roles in defence, both at the leaf and flower level. Hence, we correlated the trichome morphotypes with the production of secondary metabolites in an attempt to link these data to their potential ecological roles. Finally, we made the obtained scientific knowledge available to visitors of the Botanic Garden through the realization of new labelling dedicated to B. acetabulosa that highlights the ‘invisible’, microscopic features of the plant.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Micromorphological and phytochemical survey of Ballota acetabulosa (L.) Benth

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The trend of collecting plants and associated products is a very old one and continues to date for various purposes, including medicinal importance, food, and trade . One of the plant genera known for these potential applications is the genus Ballota , due to which there is a remarkable interest among natural product scientists toward exploring many of its species. − To date, this genus is known to have 33 species, of which the majority are located in the Mediterranean region. Two of the species from the list, i.e., Ballota limbata and Ballota aucheri, are found in Pakistan …”

Section: Introductionmentioning

confidence: 99%

“…Ballota nigra, for instance, is known for its expectorant and antiemetic effects Ballota hispanica has been reported as a sedative and an antidiabetic plant Ballota limbata, locally known as “Awan Buti” in Pakistan, has previously shown potential for the treatment of gum diseases in children and for curing wounds .…”

Section: Introductionmentioning

confidence: 99%

“…10 Ballota hispanica has been reported as a sedative and an antidiabetic plant. 5 Ballota limbata , locally known as “Awan Buti” in Pakistan, has previously shown potential for the treatment of gum diseases in children and for curing wounds. 11 An important class of bioactive compounds present in Ballota limbata consists of diterpenoids, 3 , 8 which have potential applications in inhibition of lipoxygenase.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Determination of the Absolute Configuration of Ballonigrin Lactone A Using Density Functional Theory Calculations

et al. 2023

View full text Add to dashboard Cite

We report the determination of the absolute configuration of a diterpenoid, namely, ballonigrin lactone A (BLA), by comparison of the computed optical rotations, [α]D, of its two diastereomers using density functional theory (DFT) calculations to the experimental [α]D value of +22.4. One of the diastereomers having configurations 4S, 5R, 6S, 10S, 15S was named “α-BLA,” and the other one with configuration 4S, 5R, 6S, 10S, 15R was called “β-BLA”. Six conformers for each diastereomer (α-BLA and β-BLA) of BLA were identified through their conformational analysis. [α]D values of these six conformations for each diastereomer were calculated using DFT at the mPW1PW91/6-311G(d,p)/SMDChloroform level of theory, leading to the conformationally averaged [α]D values of −96.8 for α-BLA and +65.1 for β-BLA. Thus, it was found that the experimental [α]D value of +22.4 was of 4S, 5R, 6S, 10S, 15R, i.e., β-BLA. Experimental and computed nuclear magnetic resonance (NMR) data were also compared, and this comparison was in accordance with the conclusion drawn from the comparison of [α]D values. Finally, the results were augmented with the calculation of the DP4 analysis, and the probability obtained also endorsed our earlier calculations.

show abstract

A review on traditional uses, phytochemistry and pharmacological activities of the genus Ballota

Morteza‐Semnani

Ghanbarimasir

2019

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Chemical composition and biological activity of the essential oil of Ballota hispanica (L.) Benth. growing wild in Sicily

Cited by 7 publications

References 38 publications

Micromorphological and phytochemical survey of Ballota acetabulosa (L.) Benth

Micromorphological and phytochemical survey of Ballota acetabulosa (L.) Benth

Determination of the Absolute Configuration of Ballonigrin Lactone A Using Density Functional Theory Calculations

A review on traditional uses, phytochemistry and pharmacological activities of the genus Ballota

Contact Info

Product

Resources

About