Chemical Composition and Biological Activities of<i>Carum roxburghianum</i>Benth. (Radhuni) Seeds of Three Bangladeshi Ecotypes

Paul, Bishwagith Kumer; Saleh-e-In, Moshfekus; Hassan, Shimaa M.; Rahman, Zamilur; Saha, G. C.; Roy, Sudhangshu Kumar

doi:10.1080/0972060x.2013.793983

Cited by 5 publications

(3 citation statements)

References 11 publications

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“…Minerals are essential for proper tissue functioning and a daily requirement for human nutrition (Iniaghe et al, 2009). Minerals acts as a component and activator of many plant enzymes (Paul et al, 2013). Iron is essential in immune functioning, cognitive development, temperature regulation, energy metabolism in their lower concentrations, and is required for the synthesis of haemoglobin and myoglobin while its deficiency causes anaemia (Ikem and Egiebor, 2005; Geissler and Singh, 2011).…”

Section: Minimum Bactericidal Concentration (Mbc)mentioning

confidence: 99%

“…Elevated levels of Na are linked with hypertension and high blood pressure. Potassium is required during glycogenesis, acid-base balance, regulation of osmotic pressure, nerve impulse conduction, and muscle contraction (Njuguna et al, 2013;Paul et al, 2013). Heavy metals are metallic chemical element with a relatively high density that are toxic, poisonous and harmful to human well-being at low concentrations (Sobha et al, 2007).…”

Section: Minimum Bactericidal Concentration (Mbc)mentioning

confidence: 99%

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Antibacterial Properties and Phytochemicals Screening of Tectona grandis (Teak) Leaf Extracts against Bacteria Implicated from Upper Respiratory Tract Infections

Usin¹

2022

JMR

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Upper respiratory tract infections (URTIs) commonly befalls both children and adults and is a major cause of mild morbidity. URTIs ranges from mild self-limiting diseases such as common cold to serious life-threatening illnesses such as epiglottitis. The present study was aimed to evaluate the antibacterial activities of Tectona grandis (teak) leaves extractson some pathogenic microorganisms isolated from clinical samples causingURTIs. The antibacterial activities were assayed using the agar well diffusion method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated using standard microbiological techniques. Phytochemical andmineral compositions of all the extracts were determined. Appreciable quantities of phytochemical such as saponins, tannins, flavonoids, glycosides, anthraquinone and alkaloids were present in both extracts of the plants with flavonoids having a higher percentage. Minerals such as K, Ca, Fe, Na and Fe were presented in both solvents. Heavy metals like Pb, Cd and as were presented in significant quantities in both extracts, however, high amount of the heavy metal composition was observed in the ethanol extract. The plant extracts exhibited varying degrees of concentration-based antibacterial activities against bacteria implicated from URTIs. They showed a high significant antibacterial activity against Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. Conclusively, the plant extracts contained several bioactive compounds (phytochemical), thereby validating the use of this plants for therapeutic tenacities. Also, the antibacterial activity of the leaf extracts against the test organisms also supports its usage in traditional medicine practice.

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Section: Minimum Bactericidal Concentration (Mbc)mentioning

confidence: 99%

Section: Minimum Bactericidal Concentration (Mbc)mentioning

confidence: 99%

Antibacterial Properties and Phytochemicals Screening of Tectona grandis (Teak) Leaf Extracts against Bacteria Implicated from Upper Respiratory Tract Infections

Usin¹

2022

JMR

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“…The presence of vitamins, 6-gingerol, and other polyphenolic compounds in aqueous extract has shown good antioxidant potential in DPPH free radical scavenging model. [66][67][68][69][70][71][72] C. roxburghianum seed extract possesses blood pressure lowering, vasorelaxant and cardiac modulatory potential, occurred possibly through Ca++ antagonism, nitric oxide modulatory and phosphodiesterase inhibition mechanisms. Oil from seeds reported to contain up to 80% D-carvone which possess strong antioxidant potential against in vitro DPPH, ABTS, and FRAP tests.…”

Section: -65]mentioning

confidence: 99%

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Kaushik

2017

IJGP

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Epilepsy or Apasmara is a common chronic neurological disorder affecting millions worldwide. Abnormal neuronal discharge occurs during seizures. A person with epilepsy is loaded with a variety of synthetic anticonvulsants, which has associated toxicities and degenerative effects on some essential biochemicals and brain antioxidant enzymes on prolonged use. Ketogenic and Atkins diet are sometimes prescribed by neurologists as adjuvant with modern antiepileptics, but their limited use and associated side effects have led to focus on some alternatives. Nidanparivarjan, Shodhan chikitsa, Bahiparimarjan, Rasayana chikitsa, Sattvavajaya and Avasthika chikitsa are basic approaches for treatment of disorders or ailments in Ayurveda. Rasayana chikitsa is preferred for the long-term management of epilepsy, which involves the use of Medhya Rasayana which is a collection of herbs in minute quantities such as Mandukaparni, Yashtimadhu, Guduchi, Tinospora, Ashwagandha, Shankhpushpi, Vacha, and Brahmi. Sarasvata churna is an ayurvedic formulation and as mentioned by Bhavaprakasha and Ayurvedic Formulary of India and is a compound ayurvedic formulation containing Saussurea lappa, Withania somnifera, Rock salt, Carum roxburghianum, Cuminum cyminum, Carum carvi, Piper longum, Piper nigrum, Zingiber officinale, Cissampelos pareira, Convolvulus pluricaulis, Acorus calamus, and Bacopa monnieri. Besides possessing tremendous curing potential, Sarasvata churna is not being prescribed by neurologists for the treatment of epilepsy due to lack of animal and clinical safety data. In this study, the individual component drugs of Sarasvata churna are intensively investigated on pharmacological basis for their respective role in overcoming epilepsy so as to understand the actual mechanisms behind the potential of this thousand years old remedy for epilepsy.

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