Chemical composition and biological activities of two chemotype-oils from Cinnamomum verum J. Presl growing in North Brazil

Farias, Ana Patrícia P; Monteiro, Odair dos Santos; Silva, Joyce Kelly R. da; Figueiredo, Pablo Luis B.; Rodrigues, Antônia Alice Costa; Monteiro, Ildenice Nogueira; Maia, José Guilherme S.

doi:10.1007/s13197-020-04288-7

Cited by 19 publications

(19 citation statements)

References 26 publications

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“…In addition, cinnamyl alcohol (P27/P33) was detected at trace levels ranging from 0.01-1.3%. Other alcohols, i.e., linalool and borneol, were not detected in the current study though reported in the essential oil of C. verum J. Presl in North Brazil [32], linalool in C. verum [28,30], and borneol in C. cassia [7].…”

Section: Alcoholscontrasting

confidence: 64%

Comparative Metabolite Profiling and Fingerprinting of Medicinal Cinnamon Bark and Its Commercial Preparations via a Multiplex Approach of GC–MS, UV, and NMR Techniques

et al. 2022

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Various species of cinnamon (Cinnamomum sp.) are consumed as traditional medicine and popular spice worldwide. The current research aimed to provide the first comparative metabolomics study in nine cinnamon drugs and their different commercial preparations based on three analytical platforms, i.e., solid-phase microextraction coupled to gas chromatography–mass spectrometry method (SPME/GC–MS), nuclear magnetic resonance (NMR), and ultraviolet-visible spectrophotometry (UV/Vis) targeting its metabolome. SPME/GC–MS of cinnamon aroma compounds showed a total of 126 peaks, where (E)-cinnamaldehyde was the major volatile detected at 4.2–60.9% and 6.3–64.5% in authenticated and commercial preparations, respectively. Asides, modeling of the GC/MS dataset could relate the commercial products CP-1 and CP-3 to C. cassia attributed to their higher coumarin and low (E)-cinnamaldehyde content. In contrast, NMR fingerprinting identified (E)-methoxy cinnamaldehyde and coumarin as alternative markers for C. verum and C. iners, respectively. Additionally, quantitative NMR (qNMR) standardized cinnamon extracts based on major metabolites. UV/Vis showed to be of low discrimination power, but its orthogonal projections to latent structures discriminant analysis (OPLS-DA) S-plot showed that C. iners was more abundant in cinnamic acid compared to other samples. Results of this study provide potential insights into cinnamon drugs QC analysis and identify alternative markers for their discrimination.

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Section: Alcoholscontrasting

confidence: 64%

Comparative Metabolite Profiling and Fingerprinting of Medicinal Cinnamon Bark and Its Commercial Preparations via a Multiplex Approach of GC–MS, UV, and NMR Techniques

et al. 2022

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“…The most common method used to prepare cinnamon extract (oils) is hydrodistillation, a steam distillation in a Clevenger-type apparatus [18][19][20][21][22][23][24][25]. Small fragments of bark, leaves, or fruits are subjected to extraction.…”

Section: Bioactive Compounds Determined In Cinnamon Determination Methods For Compounds Naturally Occurring In Cinnamonmentioning

confidence: 99%

“…For bark extraction, it is also possible to use a wide range of other extraction techniques, including distillation [26], steam distillation [27], supercritical CO 2 extraction [28], subcritical extraction [12,29], extraction in Soxhlet apparatus [27], water extraction [16,30], and extraction in Soxhlet apparatus. Chromatographic analysis of the obtained extract is usually carried out with the use of gas chromatography techniques, mainly GC-MS [10,[19][20][21][22][24][25][26][29][30][31], but also GC [22,28], GC-FID [19,20,23], or GCxGC-TOFMS [18]. Additionally, liquid chromatography is used for the analysis of cinnamon extracts, including HPLC [12,27], reversed-phase high-performance liquid chromatography (RP-HPLC) [13], liquid chromatography with tandem mass spectrometry (LC-MS/MS) [32], and ultraperformance liquid chromatography-high-resolution mass spectrometry (UPLC-HRMS) [33].…”

Section: Bioactive Compounds Determined In Cinnamon Determination Methods For Compounds Naturally Occurring In Cinnamonmentioning

confidence: 99%

“…All the discussed analysis methods allow the determination of a number of biologically active compounds. As previously mentioned, these are mainly cinnamaldehyde [12,[24][25][26][27][28][29][30][31]35], but also eugenol [10,[19][20][21]23,26,28], linalool [19,[21][22][23], and phenols [34], among others.…”

Section: Bioactive Compounds Determined In Cinnamon Determination Methods For Compounds Naturally Occurring In Cinnamonmentioning

confidence: 99%

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The Potential Role of Cinnamon in Human Health

Błaszczyk

Rosiak

Kałużna–Czaplińska

2021

Forests

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Cinnamon is an unusual tropical plant belonging to the Lauraceae family. It has been used for hundreds of years as a flavor additive, but it has also been used in natural Eastern medicine. Cinnamon extracts are vital oils that contain biologically active compounds, such as cinnamon aldehyde, cinnamic alcohol, cinnamic acid, and cinnamate. It has antioxidant, anti-inflammatory, and antibacterial properties and is used to treat diseases such as diabetes and cardiovascular disease. In folk medicine, cinnamon species have been used as medicine for respiratory and digestive disorders. Their potential for prophylactic and therapeutic use in Parkinson’s and Alzheimer’s disease has also been discovered. This review summarizes the available isolation methods and analytical techniques used to identify biologically active compounds present in cinnamon bark and leaves and the influence of these compounds in the treatment of disorders.

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“…The idea of using C. chinensis as a preservative was put forward to solve the environmental problems of existing wood preservatives. Compared with traditional preservatives, this type of preservative relies on natural materials (Farias et al 2020) and has a remarkable environmental protection effect (Ahmed et al 2020). But it also has the characteristics of easy degradation and a short effective period of the single active ingredient (Treu et al 2020).…”

Section: Introductionmentioning

confidence: 99%

Isolation and identification of the antibacterial compounds in Coptis chinensis for the preservation of wood

Wang

Zhao

et al. 2021

BioRes

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Wood is a biomass material that is easily eroded by wood-rotting fungi. Coptis chinensis is a natural green plant, which has an inhibitory effect on most microorganisms. Based on the highly toxic effects of the currently used wood chemical preservatives on humans, animals, and the environment, Coptis chinensis was selected to perform decay resistance experiments of wood in this paper. The active ingredients with bacteriostatic properties in Coptis chinensis were separated and screened via chemical treatment, and their structure was identified via nuclear magnetic resonance spectroscopy. The primary bacteriostatic components in Coptis chinensis were berberine hydrochloride, palmatine, and jatrorrhizine. The bacteriostatic zone experiment with a single component and different compounds for white-rot and brown-rot fungus were tested by the disc agar diffusion method. The bacteriostatic effect of berberine hydrochloride in a single active fraction was better. The three-fraction compound had the best bacteriostatic effect and was equivalent to alkaline copper quaternary. The natural active bacteriostatic fractions in Coptis chinensis had noticeable inhibitory effects on white-rot fungus (Trametes versicolor (L.) Lloyd) and brown-rot fungus (Gloeophyllum trabeum (Pers.) Murrill). The minimum bacteriostatic concentration was 0.01 g/mL. The results showed that Coptis extracts had potential as a wood protectant.

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Chemical composition and biological activities of two chemotype-oils from Cinnamomum verum J. Presl growing in North Brazil

Cited by 19 publications

References 26 publications

Comparative Metabolite Profiling and Fingerprinting of Medicinal Cinnamon Bark and Its Commercial Preparations via a Multiplex Approach of GC–MS, UV, and NMR Techniques

Comparative Metabolite Profiling and Fingerprinting of Medicinal Cinnamon Bark and Its Commercial Preparations via a Multiplex Approach of GC–MS, UV, and NMR Techniques

The Potential Role of Cinnamon in Human Health

Isolation and identification of the antibacterial compounds in Coptis chinensis for the preservation of wood

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