Chemical Composition and Antioxidant Activities of Aframomum sceptrum

Erukainure, Ochuko L.; Oke, Oluwatoyin V.; Owolabi, F.; Adenekan, O.S.

doi:10.3923/tasr.2011.190.197

Cited by 9 publications

(10 citation statements)

References 5 publications

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“…Flavonoid is also known to exhibit antimicrobial properties, while anthraquinone is known for its laxative properties. In line with Osbourn et al (2011) and Erukainure et al (2011), saponin and glycosides were detected in the seeds and fractions of A. sceptrum.…”

Section: Resultssupporting

confidence: 52%

Extraction, fractionation and assessment of antioxidant activities of active components of Aframomum sceptrum seeds

Okwuchi¹

2015

Afr. J. Biochem. Res.

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A simple procedure of extraction, fractionation and assessment of organoleptic and antioxidant properties of Aframomum sceptrum seeds was carried out, and the results were compared with a currently used synthetic antioxidant, butylated hydroxy toluene (BHT). Extraction was carried out using Soxhlet extractor and fractionation of the ethanolic extract was accomplished using vacuum liquid chromatography (VLC). Various fractions of the ethanolic extract were obtained but similar fractions were pooled together to yield six fractions (F1-F6) as guided by thin layer chromatography (TLC) analysis. Fractions obtained were subjected to sensory, chemical, spectroscopic and storage assessment in order to evaluate their antioxidant potentials. Sensory characterization and antioxidant storage tests showed that fractions F4 and F5 had non-bitter taste and yellow colour in contrast to bitter taste and dark brown colour of the crude extract. Statistical analysis (P= 0.05) showed that the antioxidant effectiveness (AE) of the fractionated extracts F4 and F5 were 62.57 and 59.13% for groundnut oil and 64.50 and 62.91% for red palm oil, respectively, and compared favourably with the standard synthetic antioxidant used. The fractions can be used to extend the shelf life of food products.

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Section: Resultssupporting

confidence: 52%

Extraction, fractionation and assessment of antioxidant activities of active components of Aframomum sceptrum seeds

Okwuchi¹

2015

Afr. J. Biochem. Res.

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“…Antioxidants protect the body against adverse effects of free radical or reactive oxygen species (ROS) generation [6], which are characterized by their ability in causing oxidative damage to the body. Several studies have shown that ROS are involved in various related physiological processes and diseases such as aging, cancer and atherosclerosis [7]. These antioxidants also play a major role in food quality preservation due to their ability to prevent oxidative deterioration of lipids [3].…”

Section: Introductionmentioning

confidence: 99%

Chemical properties of <i>Monodora myristica</i> and its protective potentials against free radicals <i>in vitro</i>

Erukainure¹,

Oke²,

Owolabi³

et al. 2012

Oxid Antioxid Med Sci

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Distortion of the balance between the production of reactive oxygen species and the body's antioxidant defenses against them produces oxidative stress, which intensifies tissue damage. Spices have been reported to possess antioxidant properties which protect against ROS. Monodora myristica is among the common spices in Nigeria with reported medicinal properties. Its proximate composition, phytochemical constituents and antioxidant activities were investigated. The proximate composition ranged from 3.06 to 52.42% with nitrogen free extract having the highest value and ash content, lowest. Phytochemical screening of the spice showed the presence of alkaloids, flavonoids, phenols, tannins and saponins. The 1,1-diphenyl-2 picrylhydrazyl (DPPH) scavenging activity ranged from 16.9 to 71.15 mg gallic acid equivalents (GAE)/g. While the reducing power compared to the standard, gallic acid ranging from 0.028 to 0.126 mg GAE/g. Monodora myristica exhibited high antioxidant activities in vitro, signifying the protective potential of the spice against free radicals. The phytochemicals, phenolic and flavonoids in particular may be responsible for these effective antioxidant properties.

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“…Alcohol has been reported to promote the generation of free radicals such as reactive oxygen species (ROS) resulting to oxidative stress, which interferes with the body's normal defense mechanism (Wu and Cederbaum 2003). ROS are involved in various related physiological processes and diseases such as aging, cardiovascular diseases, atherosclerosis, various types of cancer and diabetes (Knight 1998;Erukainure et al 2011). The body also produces ROS, which is beneficial and essential to the organism as it plays a central role in destroying foreign pathogens.…”

Section: Introductionmentioning

confidence: 99%

ANTIOXIDANT EFFECT OF PINEAPPLE (ANANAS COSMOSUS) PEEL EXTRACT ON ALCOHOL-INDUCED OXIDATIVE STRESS IN SPLENIC TISSUES OF MALE ALBINO RATS

Erukainure

Ajiboye

Okafo

et al. 2011

Journal of Food Biochemistry

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Oxidative stress was induced by oral administration of ethanol (20% w/v) at a dosage of 5 mL/kg body weight in rats. After 28 days of treatment, the rats were fasted overnight and sacrificed by cervical dislocation. Splenic tissue homogenates were used for the assessment of protein concentration, reduced glutathione (GSH), catalase, superoxide dismutase (SOD) and lipid peroxidation. Feeding on alcohol caused a significant decrease in GSH level in the group fed alcohol only, while treatment with pineapple peel extracts increased the GSH activities. No significant difference was observed in SOD levels of the negative control and group fed on only pineapple peel extract. There was an elevated catalase activity in the negative control. Pineapple peel extract significantly reduced it. Treatment with pineapple peel extracts was observed to reduce malondialdehyde (MDA) in alcohol‐fed groups. Protein concentration increased after treatment with the extracts. This study indicates the protective effect of pineapple peel extract against alcohol‐induced oxidative stress. PRACTICAL APPLICATIONS Pineapples are readily available in the tropics and subtropics almost all seasons. It can be grown in marginal conditions, with a minimum input cost. Fruits are used for human consumption as well as raw materials for most juice industries. However, its peels are not being utilized, thereby leading to a waste management problem. Utilization of the peels for medicinal purposes will therefore reduce the cost of waste management and also be of tremendous benefit to the medical world in the management of various ailments.

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Chemical Composition and Antioxidant Activities of Aframomum sceptrum

Cited by 9 publications

References 5 publications

Extraction, fractionation and assessment of antioxidant activities of active components of Aframomum sceptrum seeds

Extraction, fractionation and assessment of antioxidant activities of active components of Aframomum sceptrum seeds

Chemical properties of <i>Monodora myristica</i> and its protective potentials against free radicals <i>in vitro</i>

ANTIOXIDANT EFFECT OF PINEAPPLE (ANANAS COSMOSUS) PEEL EXTRACT ON ALCOHOL-INDUCED OXIDATIVE STRESS IN SPLENIC TISSUES OF MALE ALBINO RATS

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Chemical Composition and Antioxidant Activities of Aframomum sceptrum

Cited by 9 publications

References 5 publications

Extraction, fractionation and assessment of antioxidant activities of active components of Aframomum sceptrum seeds

Extraction, fractionation and assessment of antioxidant activities of active components of Aframomum sceptrum seeds

Chemical properties of &lt;i&gt;Monodora myristica&lt;/i&gt; and its protective potentials against free radicals &lt;i&gt;in vitro&lt;/i&gt;

ANTIOXIDANT EFFECT OF PINEAPPLE (ANANAS COSMOSUS) PEEL EXTRACT ON ALCOHOL-INDUCED OXIDATIVE STRESS IN SPLENIC TISSUES OF MALE ALBINO RATS

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Chemical properties of <i>Monodora myristica</i> and its protective potentials against free radicals <i>in vitro</i>