Chemical Composition and Antimicrobial Activity of the Essential Oil ofArtemisia lavandulaefolia

Abstract

The chemical components of the essential oil obtained from Artemisia lavandulaefolia DC. were analyzed by GC-MS. Ninety-nine compounds accounting for 94.9 % of the essential oil were identified. The major compounds in the essential oil were beta-caryophyllene (16.1 %), cis-chrysanthenol (7.0 %), 1,8-cineole (5.6 %), borneol (5.3 %), trans-beta-farnesene (5.1 %), camphor (4.9 %), yomogi alcohol (4.5 %), alpha-terpineol (3.9 %), and alpha-humulene oxide (3.3 %). The essential oil and some of its major compounds were tested for antimicrobial activity against 15 different genera of oral bacteria. The essential oil of A. lavandulaefolia exhibited considerable inhibitory effects against all obligate anaerobic bacteria (MIC values, 0.025 to 0.05 mg/mL; MBC values, 0.025 to 0.1 mg/mL) tested, while its major compounds demonstrated different degrees of growth inhibition.

Effect of oil pulling in promoting oro dental hygiene: A systematic review of randomized clinical trials

“…Eleven studies, [14][15][16][17][18][19][20][21][22][23][24] were excluded because conventional oil pulling was not part of the intervention, and four 25-28 because they were not RCTs. One study 29 was excluded because conventional cooking oil was not used as intervention, and another 30 because it was a nonhuman study. One study 31 was excluded because another intervention was used in conjunction with oil, and two 32,33 because we were unable to obtain the full text.…”

MAPK activation is necessary to the apoptotic death of KB cells induced by the essential oil isolated from Artemisia iwayomogi

“…Essential oils are commonly found in most herbal plants and are known to have a remarkable spectrum of biological activities including anticarcinogenic, antioxidant, antiinflammation, antifungal, and antibacterial activities (Buhagiar et al, 1999;Kordali et al, 2005;Cha et al, 2005a;Sylvestre et al, 2006;Monteiro et al, 2007;Dordević et al, 2007). In particular, Artemisia species are small herbs that have been used as food additives and traditional herbal medicines.…”

In vitro cytotoxicity of Artemisia vulgaris L. essential oil is mediated by a mitochondria-dependent apoptosis in HL-60 leukemic cell line

“…There is considerable evidence showing that the active compounds in the essential oils of different Artemisia species are responsible for their anti-proliferative effect on cancer cells [14-19]. Although there is no available scientific data on the cytotoxic and apoptosis inducing effects of A. vulgaris essential oil, previous evidence indicate that the aqueous methanol extract from dry leaves of this plant is cytotoxic to the human hepatocellular carcinoma cell line HepG2 that is suggested to be mediated by apoptosis [20].…”