Chemical composition and antifungal activity of essential oils from Ocimum species

Vieira, Priscila R.N.; Morais, Selene Maia de; Bezerra, Francisco H.Q.; Ferreira, Pablito Augusto Travassos; Oliveira, Isadora Rebouças Nolasco de; Silva, Maria Goretti V.

doi:10.1016/j.indcrop.2014.02.032

Cited by 65 publications

(28 citation statements)

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“…The presence of the phenylpropanoid eugenol in the essential oil from leaves of O. campechianum, as a major chemical constituent, is in accordance with previous reports (Sacchetti et al 2004, Silva et al 2004, Trevisan et al 2006, Vieira et al 2014. Earlier investigations into the essential oils of this species growing in the same place, under same conditions, have found similar chemical composition (Silva et al 2004, Trevisan et al 2006, Vieira et al 2014. It is generally admitted that the major constituents determine the biological properties of the essential oils (Riella et al 2012, Dias & Moraes 2014.…”

Section: Discussionsupporting

confidence: 92%

Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum

Ricarte

Bezerra

Romero

et al. 2020

An. Acad. Bras. Ciênc.

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The essential oils obtained by hydrodistillation from fresh leaves of Vitex agnus-castus and Ocimum campechianum, and from fresh inflorescences of Ocimum carnosum were analysed by GC-FID and GC-MS. The major components of V. agnus-castus essential oil were identified as 1,8-cineole (47.9%), terpinyl α-acetate (11.6%), sabinene (11.2%) and caryophyllene oxide (9.7%), while in the O. campechianum essential oil were eugenol (72.1%), β-elemene (6.8%), (E)-caryophyllene (6.4%) and bicyclogermacrene (5.2%). Linalool (79.0%), α-epi-cadinol (5.4%), terpinen-4-ol (3.2%) and 1,8-cineole (2.8%) were the major constituents in the O. carnosum essential oil. The essential oils were subsequently evaluated for their larvicidal and cytotoxic activities. Larval bioassay against Aedes aegypti of V. agnus-castus, O. campechianum and O. carnosum essential oils showed LC 50 values of 97.55 ± 0.35, 81.45 ± 0.35 and 109.49 ± 0.35 μg/mL, respectively. The in vitro cytotoxic activities of the essential oils has been evaluated on breast adenocarcinoma (MCF-7), lung carcinoma (NCI-H292), pro-myelocytic leukemia (HL-60), and cervical adenocarcinoma (HEP-2) human cell lines, and pro-myelocytic leukemia cells lines (HL-60) were found to be the most sensitive to all the essential oils tested than the others. This is the first report on larvicidal and cytotoxic activities of these essential oils.

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Section: Discussionsupporting

confidence: 92%

Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum

Ricarte

Bezerra

Romero

et al. 2020

An. Acad. Bras. Ciênc.

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“…Many phytochemicals have revealed to support in maintaining the balance between oxidants and antioxidants in humans and natural antioxidants are gaining significant attention amongst food dieticians, pharmacists, manufacturers and consumers because of their enormous therapeutic potential and safety (Ito et al, 1986). Several findings have proven that many medicinal plants and food crops are a rich source of many phytochemicals which have excellent antioxidant potentials (Pizzale et al, 2002;Vieira et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

“…The genus Ocimum consist of about more than 140 different species of aromatic plants and generally found in tropical and sub-tropical regions of the world (Devi, 2001 values. The essential oils from different Ocimum species have been reported to possess antimicrobial, anticonvulsant and antioxidant activities (Akinmoladun et al, 2007;Balaji et al, 2011;Singh et al, 2010;Vieira et al, 2014). A recent study by Ahmad et al, (2012) revealed the anti-diabetic activity of new constituents characterized as urs-12-en-3β,6β,20β-triol-28-oic acid, 1´´-menthyl-2glucopyranosyloxybenzoate and n-decanoyl-β-D-glucopyranosyl-(2a→1b)-β-Dglucopyranosyl-(2b→1c)-β-D-glucopyranosyl-(2c→1d)-β-D-glucopyranosyl-2d-2hydroxybenzoate, along with ursolic acid and palmityl glucoside (Ahmad et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Antioxidative potential of two chemically characterized Ocimum (Tulsi) species extracts

et al. 2017

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Background: Ocimum sanctum and Ocimum kilimandscharicum are cultivated in Indian subcontinent both for the religious and medicinal properties. Traditionally, the leaves have been reported for their enormous therapeutic potentials but the roots which are otherwise considered as a waste part have not been explored for their pharmacological activity. Methods: Total phenolic content, free radical scavenging and ferric reducing antioxidant potential of various extracts from Ocimum sanctum and Ocimum kilimandscharicum were assessed and compared. In vitro antioxidant activity was estimated spectrophotometrically and the most potent ethyl acetate extract was chemically characterized by developing the chemical fingerprint and quantifying the probable constituents with the help of HPLC/LC-MS techniques. Results: The ethyl acetate extract of both the species exhibited significant free radical scavenging potential and also reduced the ferric ions. It was observed that ethyl acetate extract have superior ferric reducing potential than other tested extracts, which were evidenced by high ferrous sulphate equivalent value of 77.05 ± 1.54 and 80.98 ± 0.80 at 100 µg/ml for O. sanctum and O. kilimandscharium respectively. The ferric reducing capacity of ethyl acetate extract for both the species was also evidenced by an elevated optical density of 1.64 ± 0.12 and 2.14 ± 0.08. Ocimum sanctum exhibited better antioxidant capacity (11.31 ± 0.20 AScE) as compared to Ocimum kilimandscharium (9.08 ± 0.27 AScE). The total phenolic and flavonoid content were estimated by spectrophotometric method and tentatively characterized by HPLC/LC-MS profiling which revealed the presence of rosmarinic acid, caffeic acid along with its derivatives such as caffeoyl-dihydroxyphenyllactoyl-tartaric acid. Conclusion: The ethyl acetate extract of both the species being rich in phenolic and flavonoid contents exhibited potent antioxidant activity. The presence of flavonoid in ethyl acetate extracts further co-relates the antioxidative properties of roots extracts. To the best of our knowledge and understanding this is the first report of comparative chemical profiling by RP-HPLC/LC-MS and antioxidant potential of roots of two Ocimum species. Peer Review Details Peer review method: Single-Blind (Peer-reviewers: 02) Peer-review policy Plagiarism software screening?: Yes Date of Original Submission: 27 July 2017 Date accepted: 23 August 2017 Peer reviewers approved by: Dr. Lili Hami Editor who approved publication: Dr. Phuc Van Pham

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“…with anti-hemorrhagic activity [44] and natural larvicide [45], in addition to estoraque (Ocimum micranthum Willd.) with its antifungal [46] and antioxidant [47] properties.…”

Section: Potential Of a Biodiversity-based Bio-economymentioning

confidence: 99%

The Amazonia Third Way Initiative: The Role of Technology to Unveil the Potential of a Novel Tropical Biodiversity-Based Economy

Nobre¹,

Nobre²

2019

Land Use - Assessing the Past, Envisioning the Future

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For the last two decades, the Amazon development debate has been torn between attempts to reconcile two rather opposing views of land use: on one hand, a vision of setting aside large tracts of the Amazon forests for conservation purposes (referred hereafter to as The First Way) and, on the other hand, seeking a 'sustainable' resource-intensive development, mostly through agriculture/livestock, energy and mining (referred hereafter to as The Second Way). The decrease of Brazilian Amazon deforestation from 2005 to 2014 (about 75% decline) opens a window of opportunity to conceive a novel sustainable development paradigm: The Amazonia Third Way initiative (A3W). It can represent a new opportunity emerging to protect the Amazon ecosystems and the indigenous and traditional peoples who are their custodians and at the same time develop a vibrant, socially inclusive biodiversity-driven 'green economy' in the Amazon by harnessing Nature's value through the physical, digital and biological technologies of the 4th Industrial Revolution (4IR). 4IR technologies are increasingly harnessing these assets across many industries from pharmaceutical to energy, food, cosmetics, materials and mobility, and making profits. A3W addresses ways to channel to the Amazon the benefits of the 4IR for the creation of bio-industries and local development as it protects the forests.

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Chemical composition and antifungal activity of essential oils from Ocimum species

Cited by 65 publications

References 29 publications

Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum

Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum

Antioxidative potential of two chemically characterized Ocimum (Tulsi) species extracts

The Amazonia Third Way Initiative: The Role of Technology to Unveil the Potential of a Novel Tropical Biodiversity-Based Economy

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