2024
DOI: 10.1590/1519-6984.253616
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Chemical characterization and effects of volatile oil of Alpinia zerumbet on the quality of collagen deposition and caveolin-1 expression in a muscular fibrosis murine model

Abstract: This study evaluated the effect of the volatile oil of Alpinia zerumbet (VOAz) on caveolin-1 gene expression and muscular fibrosis. The rats were immobilized to induce fibrosis of the gastrocnemius muscle, and they were treated with VOAz. Collagen quality was assessed by histology and the expression of the caveolin-1 (CAV-1) gene was evaluated using qPCR. Histomorphological analysis indicated a significant reduction in the perimeter, width, and intensity of collagen in the treated groups, thus showing that the… Show more

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Cited by 2 publications
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“…Shell ginger originated from the East Indies [ 2 ] and is native in areas ranging from South Japan to Taiwan and from South China to the Northern Peninsula [ 1 ]. The plant has also been introduced to Brazil, where it has since naturalized [ 3 ]. Therefore, A. zerumbet is currently found in the subtropical and tropical areas of South America, Oceania and Asia [ 4 ] and is variously known as Vindicá (Amazon) [ 5 ], Colônia (Brazil) [ 6 ], Yàn Shān jiāng (China) [ 7 ], yellow ginger (Fiji) [ 8 ], Chatiun in Hindi (India) [ 9 ], Punnag-champa in Bengal (India) [ 10 ], Gettō (Japan) [ 11 ], Sannin (Okinawa, Japan) [ 11 ], Atoumo (Martinique, French West Indies) [ 12 ], Yuetao (Taiwan) [ 1 ], and Riềng đẹp (Vietnam) [ 13 ].…”
Section: Introductionmentioning
confidence: 99%
“…Shell ginger originated from the East Indies [ 2 ] and is native in areas ranging from South Japan to Taiwan and from South China to the Northern Peninsula [ 1 ]. The plant has also been introduced to Brazil, where it has since naturalized [ 3 ]. Therefore, A. zerumbet is currently found in the subtropical and tropical areas of South America, Oceania and Asia [ 4 ] and is variously known as Vindicá (Amazon) [ 5 ], Colônia (Brazil) [ 6 ], Yàn Shān jiāng (China) [ 7 ], yellow ginger (Fiji) [ 8 ], Chatiun in Hindi (India) [ 9 ], Punnag-champa in Bengal (India) [ 10 ], Gettō (Japan) [ 11 ], Sannin (Okinawa, Japan) [ 11 ], Atoumo (Martinique, French West Indies) [ 12 ], Yuetao (Taiwan) [ 1 ], and Riềng đẹp (Vietnam) [ 13 ].…”
Section: Introductionmentioning
confidence: 99%