Chemical characterisation and hypolipidaemic effects of two purified <i>Pleurotus eryngii</i> polysaccharides

Xing, Jin; Wang, Qilong; Yang, Xia; Guo, Min; Li, Wenjing; Shi, Jixiang; Adu‐Frimpong, Michael; Xu, Ximing; Deng, Wenwen; Yu, Jiangnan

doi:10.1111/ijfs.13821

Cited by 22 publications

(10 citation statements)

References 49 publications

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“…The IR spectroscopy indicated that SMP‐1 possessed typical absorption peaks of polysaccharides in the range of 4000–400 cm −1 (Figure c). It showed broad and intense absorption bands at 3,436.39 and 2,924.89 cm −1 , which were generated by the stretching vibration of O–H and C–H, respectively (Jin et al, ). The strong absorptions at 1,750–1,600 cm −1 could be attributed to the C=O stretching vibration of the carboxyl group (Ayyappan, Sundaraganesan, Aroulmoji, Murano, & Sebastian, ).…”

Section: Resultsmentioning

confidence: 99%

Structural characterization and hypolipidemic activities of purified stigma maydis polysaccharides

Deng

Yang

Zhu

et al. 2019

Food Science & Nutrition

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This study aimed to investigate structural features and antihyperlipidemic effects of the stigma maydis polysaccharide, termed SMP‐1. This polysaccharide was composed of D‐mannose, L‐rhamnose, D‐glucose, D‐galactose, L‐arabinose, D‐xylose, and D‐galacturonic acid, with a molar ratio of 1.00:0.21:1.41:1.44:0.70:0.44:0.56. The SMP‐1 was mainly bonded by (1 → 6) and (1 → 3) linkages, with various monosaccharides being evenly distributed in the main and side chains. Moreover, SMP‐1 had neither triple‐helical structure nor molecular aggregation. Importantly, the SMP‐1 could effectively bind the bile acids in vitro and significantly lower the total cholesterol, triglyceride, low‐density lipoprotein cholesterol levels, and moderately increase the high‐density lipoprotein cholesterol level in poloxamer 407‐induced hyperlipidemic mice. Moreover, pretreatment with SMP‐1 (≥300 mg/kg) could remarkably reduce fat accumulation and restore hepatocyte morphology in the liver of hyperlipidemic mice. Altogether, these findings indicated that SMP‐1 could be developed as a safe and effective food supplement for preventing and treating hyperlipidemic disorders.

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Section: Resultsmentioning

confidence: 99%

Structural characterization and hypolipidemic activities of purified stigma maydis polysaccharides

Deng

Yang

Zhu

et al. 2019

Food Science & Nutrition

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“…The main animal polysaccharides are glycosaminoglycans (Garcia‐Bayona & Comstock, 2019), rich in cell surfaces and pericellular matrices, and glycogen, a starch‐like mammalian storage polysaccharide. Fungi used in fermentation usually found in the end products and their polysaccharides contribute to human diets (Jin et al., 2018). Yeast in fermented bread possesses a cell wall that is composed of alpha‐mannan (mannose polysaccharide), which is large enough to activate the pathway of microbial community members to degrade it (Cuskin et al., 2015).…”

Section: Carbohydrates In the Intestinementioning

confidence: 99%

Regulation effects of indigestible dietary polysaccharides on intestinal microflora: An overview

Ahmed

Yao

et al. 2020

J. Food Biochem.

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The human intestinal contains rich and diverse microbiota that utilizes a variety of polysaccharides. The intestinal microflora extends the metabolic functions of the body, obtaining energy from indigestible dietary polysaccharides. It is not only a highly competitive environment but also a comprehensive collaboration for these polysaccharides, as the microbiota work to maximize the energy harvested from them through the intestine. Indigestible dietary polysaccharides help to manage colon health and host health by affecting the gut microbial population. These polysaccharides also influence the metabolic activity of the intestinal microbiota by stimulating the formation of SCFAs. Most of these metabolic activities affect host physiology because the epithelium absorbs secondary metabolites and end products or transports them to the liver, where they could exert other beneficial effects. This article reviews the carbohydrates existing in the human intestine, the regulating actions of indigestible polysaccharides on intestinal microflora, and the molecular basis of the degradation process of these polysaccharides. Practical applications Large deals of researches have shown that indigestible polysaccharides possess an outstanding regulation effect on the intestinal microflora, which indicates that indigestible polysaccharides have the potential to be used as prebiotics in the functional food and pharmaceutical industries. However, it is not clear how gut microbiota metabolizes these dietary polysaccharides, and how the resulting gut metabolites may further affect the intestinal microflora population and metabolism. This paper reviews the indigestible dietary polysaccharides existing in the human intestine, the regulation of polysaccharides on gut microbiota, and the molecular basis of the degradation process of these polysaccharides. This review helps to better understand the relationship between indigestible dietary polysaccharides and intestinal microflora, which will provide powerful evidence for the potential use of these polysaccharides as functional foods.

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“…Medical mushroom polysaccharides are a class of biopolymers with high value and wide industrial applications [9,10]. The polysaccharides have many biomedical activities, including lowering blood sugar and antitumor and immunomodulating activities [11,12,13,14,15]. Mushroom polysaccharides can be used as drugs to treat diabetes, cancer, and other diseases.…”

Section: Introductionmentioning

confidence: 99%

Optimization of Polysaccharide Production from Cordyceps militaris by Solid-State Fermentation on Rice and Its Antioxidant Activities

Wang

Zhang

et al. 2019

Foods

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Polysaccharides are an important class of bioactive components of medical mushroom and herbs and are now used as natural drugs or dietary supplements on a global scale. In this paper, we aimed to increase the polysaccharide production of Cordyceps militaris and the antioxidant activities of fermented rice by solid-state fermentation. The media components and culture condition were optimized by orthogonal design and mono-factor tests using rice as the raw material. The optimal media consisted of (g/L): rice (50), fructose (7), glycerin (7), peptone (1), MgCl2 (0.11), VB1 (0.05), VB2 (0.05), CaCl2 (1.5), corn bran (6), and a water–materials ratio of 100%. The fermentation condition was as follows: inoculum volume of 5.5% (v/w), rice weight of 50 g in one bowl with a diameter of 120 mm and a depth of 90 mm, incubation temperature of 26 °C, and incubation time of seven days. Under the optimized condition, the maximal C. militaris polysaccharide content and free radical scavenging ratio were 68.3 mg/g dry substrate and 98.9%, respectively. This study provides a new strategy for the production of healthy food from traditional food.

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Chemical characterisation and hypolipidaemic effects of two purified Pleurotus eryngii polysaccharides

Cited by 22 publications

References 49 publications

Structural characterization and hypolipidemic activities of purified stigma maydis polysaccharides

Structural characterization and hypolipidemic activities of purified stigma maydis polysaccharides

Regulation effects of indigestible dietary polysaccharides on intestinal microflora: An overview

Optimization of Polysaccharide Production from Cordyceps militaris by Solid-State Fermentation on Rice and Its Antioxidant Activities

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