Chemical Changes in the Body Occurring as the Result of Vomiting

Hartmann, Alexis F.; Smyth, Francis Scott; Moser, Anna E.

doi:10.1001/archpedi.1926.04130070008001

Cited by 18 publications

(5 citation statements)

References 20 publications

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“…This disappearance of urinary chloride associated with loss of chloride by vomiting is very similar to the findings of Hartmann and Smyth (28) in various types of vomiting in infants. Apparently when the level of blood chloride is reduced below a certain threshold little or no chloride is found in the urine.…”

Section: Resultssupporting

confidence: 89%

Studies in So-Called Water Intoxication

Smyth¹,

Deamer²,

Phatak³

1933

J. Clin. Invest.

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Section: Resultssupporting

confidence: 89%

Studies in So-Called Water Intoxication

Smyth¹,

Deamer²,

Phatak³

1933

J. Clin. Invest.

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“…The vomitus of uremic patients, although not a negligible source of Cl loss, is usually not an important one. This is clearly demonstrated in table 5. In this table urine and vomitus for the same days have been compared with respect to volume, Cl concentration and total excretion and, in some instances, free and total hydrochloric acid titrations.…”

mentioning

confidence: 89%

Total Acid-Base Equilibrium of Plasma in Health and Disease

Peters¹,

Wakeman²,

Lee³

1929

J. Clin. Invest.

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“…At that time, however, we were not as convinced as we are at present of the necessity of alkali in extreme cases of diabetic acidosis, and feared the development later of alkalosis. It is very doubtful whether moderate alkalosis does any more harm than moderate acidosis, and certainly extreme alkalosis has been observed in cases of pyloric stenosis (6) with little in the way of alarming symptoms. Similarly marked increase in plasma BHCO3 developed in Case 1 on April 4, 1928, after combined insulin and alkali treatment without symptoms or apparent harm.…”

Section: U8mentioning

confidence: 99%

Chemical Changes Occurring in the Body as the Result of Certain Diseases

Hartmann¹,

Darrow²,

Morton³

1928

J. Clin. Invest.

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In the first paper (1) of this series, the composition of the plasma was studied in cases of "acidosis" due chiefly to diarrhea and anhydremia. In contributing to the disturbances in the acid-base balance, the following factors were considered significant: (a) loss of BHCO3 from the plasma by way of the pancreatic and intestinal secretions and diarrheal stools; (b) functional renal insufficiency (depending presumably chiefly on anhydremia and oliguria) leading to diminished excretion of acid neutralized by ammonia, and consequent failure to support diminished plasma BHCO3, and (c) the excretion of BHCO3 as such into the urine during periods of increased osmotic pressure in the plasma due either to loss of plasma water resulting from diarrhea or to salt administration or both. Effective treatment of severe cases of acidosis of this type seemed to require alkali as well as water administration. Salt administration was considered contraindicated in the presence of high plasma chloride and low bicarbonate.In the second paper (2) the composition of the plasma in cases of nephritis was studied. It was concluded that when marked changes from the normal occurred in acute hemorrhagic nephritis, such symptoms as vomiting and diarrhea, edema and oliguria, and convulsions were responsible. In cases of chronic nephritis with renal damage, the characteristic plasma changes seemed due to a faulty secretion of urine, which led to a retention of phosphoric and sulfuric acid and a loss of plasma BCI and BHCO3. The resultant low electrolyte con-257

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Chemical Changes in the Body Occurring as the Result of Vomiting

Cited by 18 publications

References 20 publications

Studies in So-Called Water Intoxication

Studies in So-Called Water Intoxication

Total Acid-Base Equilibrium of Plasma in Health and Disease

Chemical Changes Occurring in the Body as the Result of Certain Diseases

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