Chemical and biochemical activities of sonochemically synthesized poly(N-isopropyl acrylamide)/silica nanocomposite

Chowdhury, Pranesh; Saha, Swadhin K.; Guha, Arun K.; Saha, S. K.

doi:10.1016/j.apsusc.2012.08.062

Cited by 17 publications

(15 citation statements)

References 25 publications

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“…This methodology employs an initiator and vinyl monomers. For SiO 2 and Fe 3 O 4 NPs, the functionalization of their surface with crosslinking moieties can be achieved by tethering a silane agent with vinyl terminals as MPS [ 140 , 158 ], vinyltrimethoxysilane [ 159 ], etc.…”

Section: Hybrid Nanogelsmentioning

confidence: 99%

“…The average thickness of the polymer coating was in the order of 90 nm. The synthesized hybrid material exhibited superior pH sensitivity, biocompatibility and antibacterial activity compared to the materials prepared by other techniques [ 158 ]. Another example is the synthesis of core-shell hybrid nanogels formed by a nanostructured inorganic silica core and an organic pH-responsive PDEAEMA coating via free radical co-polymerization through an oil-in-water emulsion technique of the cationic monomer 2-(diethylamino)ethyl methacrylate (DEAEM) and the monomeric silica precursor vinyltrimethoxysilane in the presence of PEGMA and triethylene glycol dimethacrylate linkers.…”

Section: Core-shell Nanoparticlesmentioning

confidence: 99%

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Design, Synthesis and Architectures of Hybrid Nanomaterials for Therapy and Diagnosis Applications

2018

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Hybrid nanomaterials based on inorganic nanoparticles and polymers are highly interesting structures since they combine synergistically the advantageous physical-chemical properties of both inorganic and polymeric components, providing superior functionality to the final material. These unique properties motivate the intensive study of these materials from a multidisciplinary view with the aim of finding novel applications in technological and biomedical fields. Choosing a specific synthetic methodology that allows for control over the surface composition and its architecture, enables not only the examination of the structure/property relationships, but, more importantly, the design of more efficient nanodevices for therapy and diagnosis in nanomedicine. The current review categorizes hybrid nanomaterials into three types of architectures: core-brush, hybrid nanogels, and core-shell. We focus on the analysis of the synthetic approaches that lead to the formation of each type of architecture. Furthermore, most recent advances in therapy and diagnosis applications and some inherent challenges of these materials are herein reviewed.

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Section: Hybrid Nanogelsmentioning

confidence: 99%

Section: Core-shell Nanoparticlesmentioning

confidence: 99%

Design, Synthesis and Architectures of Hybrid Nanomaterials for Therapy and Diagnosis Applications

2018

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“…SiO 2 nanoparticles have been extensively used in nanocomposite materials due to their nanoscale size and high specific surface area [21]. SiO 2 nanoparticles can improve various properties of polymeric nanocomposite such as mechanical property, thermal property, rheological property, and chemical property with control of these properties base on their compositions, dimensions, and structures of the core and shell [22][23][24]. Various techniques such as in situ polymerization process, melt-compounding and mechanical-mixing have been employed to synthesize polymer nanocomposites [25].…”

Section: Research Significancementioning

confidence: 99%

Novel Synthesis, Characterization and Amoxicillin Release Study of pH-Sensitive Nanosilica/Poly(acrylic acid) Macroporous Hydrogel with High Swelling

et al. 2022

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The effect of SiO2 nanoparticles on the formation of PAA (poly acrylic acid) gel structure was investigated with seeded emulsion polymerization method used to prepare SiO2/PAA nanoparticles. The morphologies of the nanocomposite nanoparticles were studied by transmission electron microscopy (TEM). Fourier-transform infrared (FTIR) spectroscopy results indicated that the PAA was chemically bonded to the surface of the SiO2 nanoparticles. Additionally, the resulting morphology of the nanocomposite nanoparticles confirmed the co-crosslinking role of the SiO2 nanoparticles in the formation of the 3D structure and hydrogel of PAA. SiO2/PAA nanocomposite hydrogels were synthesized by in situ solution polymerization with and without toluene. The morphology studies by field emission scanning electron microscopy (FESEM) showed that when the toluene was used as a pore forming agent in the polymerization process, a macroporous hydrogel structure was achieved. The pH-sensitive swelling behaviors of the nanocomposite hydrogels showed that the formation of pores in the gels structure was a dominant factor on the water absorption capacity. In the current research the absorption capacity was changed from about 500 to 4000 g water/g dry hydrogel. Finally, the macroporous nanocomposite hydrogel sample was tested as an amoxicillin release system in buffer solutions with pHs of 3, 7.2, and 9 at 37 °C. The results showed that the percentage cumulative release of amoxicillin from the hydrogels was higher in neutral and basic mediums than in the acidic medium and the amoxicillin release rate was decreased with increasing pH. Additionally, the release results were very similar to swelling results and hence amoxicillin release was a swelling controlled-release system.

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“…The mechanism of action is attributed to the slow release of silver ions from the polymer matrix, which is known to exhibit bactericidal properties due to either inhibition of the respiratory enzymes, disruption of metabolic activities, or the nucleic acid damage leading to consequent death of the microorganism [ 81 , 82 ]. Polymer (poly(N-isopropyl acrylamide))-coated silica nanoparticles have also demonstrated efficacy against Bacillus species (vegetative cells) as assessed using a preliminary growth inhibition assay via disc diffusion [ 83 ]. However, quantification of reduction in bacterial population was not conducted.…”

Section: Effect Of Antimicrobial Structures On Biofilmsmentioning

confidence: 99%

Nature-Inspired Antimicrobial Surfaces and Their Potential Applications in Food Industries

Soni

Brightwell

2022

Foods

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Antimicrobial resistance (AMR) is a growing global concern and has called for the integration of different areas of expertise for designing robust solutions. One such approach is the development of antimicrobial surfaces to combat the emerging resistance in microbes against drugs and disinfectants. This review is a compressive summary of the work done in the field of material science, chemistry, and microbiology in the development of antimicrobial materials and surfaces that are inspired by examples in nature. The focus includes examples of natural antimicrobial surfaces, such as cicada wings or nanopillars, dragonfly wings, shrimp shells, taro leaves, lotus leaves, sharkskin, gecko skin, and butterfly wings, along with their mechanism of action. Techniques, compositions, and combinations that have been developed to synthetically mimic these surfaces against bacterial/viral and fungal growth in food-processing areas have also been discussed. The applications of synthetic mimics of natural antimicrobial surfaces in food-processing environments is still a naïve area of research. However, this review highlights the potential applications of natural antimicrobial surfaces in the food-processing environment as well as outlines the challenges that need mitigations.

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Chemical and biochemical activities of sonochemically synthesized poly(N-isopropyl acrylamide)/silica nanocomposite

Cited by 17 publications

References 25 publications

Design, Synthesis and Architectures of Hybrid Nanomaterials for Therapy and Diagnosis Applications

Design, Synthesis and Architectures of Hybrid Nanomaterials for Therapy and Diagnosis Applications

Novel Synthesis, Characterization and Amoxicillin Release Study of pH-Sensitive Nanosilica/Poly(acrylic acid) Macroporous Hydrogel with High Swelling

Nature-Inspired Antimicrobial Surfaces and Their Potential Applications in Food Industries

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