Chemical and Antimicrobial Properties of Leaf Extracts of Zapoteca portoricensis

Agbafor, K. N.; Akubugwo, E. I.; Ogbashi, M.E.; Aja, P. M.; Ukwandu, C.C.

doi:10.3923/rjmp.2011.605.612

Cited by 33 publications

(16 citation statements)

References 5 publications

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“…Study has shown that leaf extract of Z. portoricensis significantly increased malondialdehyde (MDA) levels and decrease superoxide dismutase (SOD) and catalase (CAT) activities in experimental rats. 23,24 This is an indication that the extract has antioxidative potential which is attributed to the presence of flavonoids in the extract, thus supports our present findings. The leaf extract of C. roseus (L. rosea) has been shown to reduce the serum cholesterol and total triglycerides levels in normal rats.…”

Section: Total Antioxidant Capacity (Tac)supporting

confidence: 91%

Antioxidant, Total Phenolic and Flavonoid Content of Selected Nigerian Medicinal Plants

Agbo

Uzor

Nneji

et al. 2015

Dhaka Univ. J. Pharm. Sci

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Plant phenolics and flavonoids play a great role in scavenging free radicals in the body and act as antioxidants. Thus their determination is sometimes nedded. Total antioxidant capacity, total phenolic and flavonoid contents of the extracts of 10 medicinal plants (Lochnera rosea, Allamanda cathartica, Asplenium platyneuron, Euphorbia prostrate, Baphia nitida, Crotolaria retusa, Zapoteca portoricensis, Platycerium bifurcatum, Mussaenda afzelii and Craterosiphon scandens) from 7 botanical families growing in the tropical rainforest of Nigeria were included in this study. The total antioxidant capacity of the extracts was assessed by using the phosphomolybdate method. The phenolic content was determined by using Folin-Ciocalteau assay, while the total flavonoid was determined by the aluminium chloride colorimetric assay. The results obtained showed that the total antioxidant capacity for all the extracts were in the range of 0.888 ± 0.75 to 0.938 ± 0.00 mg EAA/g. The results showed that E. prostrate, P. bifurcatum and A. platyneuron were found to be the richest source of phenolic (97.77 ± 0.77, 87.62 ± 1.22 and 82.33 ± 0.30 mg GAE/g) while B. nitida and M. afzelii had the least total phenolic content (11.67 ± 0.09 and11.18 ± 0.30 mg GAE/g). The highest total flavonoid content was revealed in P. bifurcatum (648.67 ± 12.3 mg QE) while M. afzelii also had the least total flavonoid content (3.67 ± 0.00 mg QE/g). The ratio of flavonoid to the phenolic in each extract was also determined to ascertain extracts that are rich in flavonoids.

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Section: Total Antioxidant Capacity (Tac)supporting

confidence: 91%

Antioxidant, Total Phenolic and Flavonoid Content of Selected Nigerian Medicinal Plants

Agbo

Uzor

Nneji

et al. 2015

Dhaka Univ. J. Pharm. Sci

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“…It cantreat respiratory tract infectionsand used in treating wounds, and sores 51 . Extracts had an antioxidant potential 50 .The fresh calyces are rich in riboflavin, niacin and iron 52 .HatilHashim, et al(2006) 49 evaluated the antibiotic effect of Hibiscus sabdariffa (karkade), E-coli showed higher resistance to the plant extracts whereas Pseudomonas aeruginosa is more sensitive. An odd study ofAmos(2003) 53 reported that aqueous extract of Hibiscus sabdariffa(karkade) calyces may contain psychoactive substances, which are sedative in nature with possible neuroleptic properties.The present study was at comparing the levels of some major constituents of karkade (Hibiscus sabdariffa L. -Roselle plant) within two varieties, the red and white dry calyces, aiming at evaluating the nutritional value of this Sudanese plant fruits.…”

Section: Medicinal Applications Of Karkadementioning

confidence: 99%

A Comparative Study on Some Major Constituents of Karkade (Hibiscus Sabdariffa L. Â€“ Roselle Plant)

Ahmed

Satti

Eltahir

2019

Int J Life Sci Pharm Res

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Hibiscus sabdariffaplant{Botanical name: Hibiscus sabdariffa Linne (Malvaceae)},commonly known as "rossell" in the English language, and "karkade" in Arabic. It is a plant widely cultivated in both tropical and subtropical regions including Sudan, (Kordofan and Darfur regions). Karkade calyces are used as a cold or hot drink when soaked in water, having refreshing, nutritional and medicinal characteristics. This study aimed at investigating the levels of some major constituents of the rossell calyces and compares their levels within the two varieties (Red and white calyces). The phytochemical, proximate and the specific analyses showed that the calcium levels in Sudanese karkade (25 mg/100g and 25.5 mg/100g in red calyces and white calyces, respectively) were lower than the levels reported by the previous studies, but the iron levels (55.5 mg/100g and 30.5 mg/100g ) were higher than levels reported by the previous studies. More investigations may be required to interpret this low level of calcium in some Sudanese karkade varieties. The anthocyanin levels (1.8% and 1.05% in red calyces and white calyces, respectively), and the vitamin C levels (16.5 mg/100g and 16.9 mg/100g) were approximately similar in both red and white karkade calyces, but the level of hibiscus acid of the red calyces was lower than its level in the white karkade calyces. The notable variations between results reported in literature about karkade (Hibiscus) constituents may be due to some factors include the variations of the genotypes, environmental and botanical nature of the tested samples, besides the use of different methodologies by researchers concerning laboratory techniques and the sampling collection methods.

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“…Medicinal plants are the resources of promising drugs for many diseases. The biological and pharmacological properties of many plants are still unknown (Ayyanar and Ignacimuthu, 2008;Agbafor et al, 2011;Roy et al, 2011;Vinoth et al, 2011;Mishra and Mishra, 2011). World-over, the scientists are exploring the possibilities of utilizing or finding out pharmacologically active compounds from medicinal plants (Agbafor et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…The biological and pharmacological properties of many plants are still unknown (Ayyanar and Ignacimuthu, 2008;Agbafor et al, 2011;Roy et al, 2011;Vinoth et al, 2011;Mishra and Mishra, 2011). World-over, the scientists are exploring the possibilities of utilizing or finding out pharmacologically active compounds from medicinal plants (Agbafor et al, 2011). For example, screening of medicinal plants for their phytochemicals, antioxidant, anticancer and antimicrobial activities is the prime concern for finding out an effective phytochemically active principle (Ayyanar and Ignacimuthu, 2008;Agbafor et al, 2011;Roy et al, 2011;Vinoth et al, 2011;Mishra and , 2011).…”

Section: Introductionmentioning

confidence: 99%

“…World-over, the scientists are exploring the possibilities of utilizing or finding out pharmacologically active compounds from medicinal plants (Agbafor et al, 2011). For example, screening of medicinal plants for their phytochemicals, antioxidant, anticancer and antimicrobial activities is the prime concern for finding out an effective phytochemically active principle (Ayyanar and Ignacimuthu, 2008;Agbafor et al, 2011;Roy et al, 2011;Vinoth et al, 2011;Mishra and , 2011). Mishra Majority of these kind of works are concerned with the study of aqueous or solvent extracts of plant parts and testing them individually for selective pharmacological activities, such as antibacterial (Mishra and Mishra, 2011), hepatoprotective (Dhanasekaran and Ganapathy, 2011), hypoglycemic and hypolipidemic activities (Sharma et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

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Cytotoxicity and antibacterial activities of methanol extract of Cochlospermum tinctorium roots and its fractions

Muhammad¹,

Taura²,

Abubakar³

et al. 2020

Adv Pharm J

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Background: It is well-known fact that medicinal plants are the resources of promising drugs for many ailments. Although, a number of research have been conducted on these plants, however, study related to their cytotoxic and antibacterial activity is of paramount important due to worldwide increase microbial resistance to antibiotics. Objective: The objective of present study was to determine the cytotoxicity and antibacterial activities of Cochlospermum tinctorium roots extract against some clinical isolates of bacteria. Water Material and Methods: and methanol were used in extraction of roots by percolation. The antibacterial activity Cochlospermum tinctorium was carried out using agar well diffusion technique against , , , and E. coli Proteus specie K. pneumoniae P. aeruginosa S. aureus, the minimum inhibitory concentration and the minimum bactericidal concentration were also determined using standard procedure The extracts were also subjected to Phytochemical Screening, Brine-shrimp lethality assay, the Lc 50 values were determined by linear regression analysis method. The result of phytochemical Results: screening revealed the presence of secondary metabolites, the result of antibacterial activity ranged from 7.23±0.20mm to 32.67±0.58mm inhibition zones, N-hexane extract have the highest zone of inhibition (32.67±0.58mm) against at 2000μg/ml concentrations, the extract was active on all the tested K. pneumoniae microorganisms at different concentrations, the MIC was lowest for at (62.5µg /ml) and highest for K. pneumoniae S. aureus E. coli K. pneumoniae and at (125µg/ml), the MBC result showed that, the extract was bactericidal to at (62.5 µg/ml followed by at (125µg/ml) and at (250µg/ml), the cytotoxicity of the plant extract (LC50) S. aureus E. coli showed that, the plant was weakly toxic. These findings therefore support the local use of Conclusion: C. tinctorium root extracts for the treatment of bacterial infections in Northern Nigeria.

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Chemical and Antimicrobial Properties of Leaf Extracts of Zapoteca portoricensis

Cited by 33 publications

References 5 publications

Antioxidant, Total Phenolic and Flavonoid Content of Selected Nigerian Medicinal Plants

Antioxidant, Total Phenolic and Flavonoid Content of Selected Nigerian Medicinal Plants

A Comparative Study on Some Major Constituents of Karkade (Hibiscus Sabdariffa L. Â€“ Roselle Plant)

Cytotoxicity and antibacterial activities of methanol extract of Cochlospermum tinctorium roots and its fractions

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