Cheilitis granulomatosa: A case report with review of literature

Vibhute, Nupura; Vibhute, Aniket H; Daule, Nilima R

doi:10.4103/0019-5154.110858

Cited by 10 publications

(11 citation statements)

References 17 publications

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“…Also, they are applied extensively in organic composition. 23,24 A lot of efforts have been devoted to synthesize bis-porphyrinodimethine cyanine dye 8 by reaction of compound 7 with two moles of 1-formyl porphyrin in N,N-dimethylformamide in the presence of a catalytic quantity of piperidine under nitrogen gas for 24 h, affording a good yield. Structure of 8 was based on it spectral and analytical analyses.…”

Section: Resultsmentioning

confidence: 99%

Thiocarbamoyl in synthesis of the absorbent bis-mono and dimethine cyanine dyes incorporating porphyrin, thiazoles, thiazolones, thiadiazoles, pyrazoles and pyrazolones

El‐Mekawy

Fadda

2017

RSC Adv.

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In this study, we have introduced an outlook dealing with synthetic heteroarenium-substituted pyridines 1 that are suitable as starting materials for the synthesis of a potential new thiocarbamoyl derivative 3 that may be of value in preparative organic and biological chemistry. Herein, a new series of twelve bis-mono and dimethine cyanine dyes incorporating different heterocyclic compounds were designed by efficient and simple reaction of compound 3 with various organic reagents to overcome the obstacles of energetic reactions, because they took long times. Moreover, the electronic behaviors of these compounds were studied because of their significant activity in many medical and other fields. The photosensitizers were elucidated by spectral and analytical analyses.

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Section: Resultsmentioning

confidence: 99%

Thiocarbamoyl in synthesis of the absorbent bis-mono and dimethine cyanine dyes incorporating porphyrin, thiazoles, thiazolones, thiadiazoles, pyrazoles and pyrazolones

El‐Mekawy

Fadda

2017

RSC Adv.

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“…The etiology of MC is poorly understood, but has been associated with genetic 7 , allergic 8 , and infectious 9 factors. Some cases may demonstrate an autosomal dominant inheritance pattern, with the responsible gene mapping to chromosome 9p11.…”

Section: Discussionmentioning

confidence: 99%

Miescher’s cheilitis: A case report with literature review

Adhikari

Shah

2018

J Pathol Nep

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Miescher’s cheilitis is an inflammatory disorder characterized by chronic lip swelling due to granulomatous inflammation. It is rare disorder first described by Miescher in 1945. It is monosymptomatic form of Melkersson-Rosenthal syndrome. We report a case of Miescher’s cheilitis in a 59-year old lady presented with recurrent swelling and erythema of upper lip and submental area with no features of facial palsy and fissuring of tongue. Laboratory tests including serum complement C3, C4 and C1 esterase inhibitor functional were within normal limits. The biopsy from the upper lip revealed dermal edema, dilated lymphatic channels and multiple granulomas. After exclusion of other causes of orofacial granulomatosis, the diagnosis of Miescher’s cheilitis was made. Patient was treated with oral hydroxychloroquine and topical tacrolimus and mometasone cream with gradual improvement.

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“…As stated before, Melkersson–Rosenthal syndrome is a rare disease which includes a triad of symptoms: facial nerve palsy, lingua plicata, and facial oedema [ 5 , 6 ]. Autosomal dominant inheritance with incomplete penetrance is well documented.…”

Section: Discussionmentioning

confidence: 99%

Melkersson–Rosenthal syndrome as an early manifestation of mixed connective tissue disease

Jasińska¹,

Boczon²

2015

Eur J Med Res

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Purpose of reviewWe aim to illustrate the potential viability of MCTD as an underlying aetiology of Melkersson–Rosenthal syndrome. The case is probably the first description available in the literature of the Melkersson–Rosenthal as an early manifestation of mixed connective tissue disease.Recent findingsThe Melkersson–Rosenthal syndrome consists of a triad of recurrent lip and/or face swelling, fissured tongue, and intermittent facial palsy. Mixed connective tissue disease is a multisystemic disorder with overlapping features of systemic lupus erythematosus, scleroderma, and polymyositis, and is differentiated from them by a high titer of antibodies to ribonucleoprotein. The paper presents a case report of Melkersson–Rosenthal syndrome with an onset in childhood that derived from vasculitis that turned out to be an early manifestation of mixed connective tissue disease. We used MRI to evaluate patient’s brain structure and Immunoblot Ena Profil 1 test to test serum autoantibodies level. The patient has a typical for Melkersson–Rosenthal syndrome triad of symptoms: bilateral facial nerve palsy, lingua plicata and facial oedema. Both TC and MRI of the head show no changes as well as laboratory tests except Anti-SS-A (Anti-Ro) and Anti-RNP autoantibody serum level that was highly positive.SummaryNeurological involvement of the MCTD usually includes, according to the frequency of the occurrence, trigeminal neuralgia, headaches, sensorineural hearing, cerebral haemorrhage, transverse myelitis, cauda equina syndrome, retinal vasculitis, progressive multifocal encephalopathy, and demyelinating neuropathy. For clinical practice it is important to remember that Melkersson–Rosenthal syndrome can also be the neurological manifestation of MCTD, especially when accompanied by other systemic symptoms.

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Cheilitis granulomatosa: A case report with review of literature

Cited by 10 publications

References 17 publications

Thiocarbamoyl in synthesis of the absorbent bis-mono and dimethine cyanine dyes incorporating porphyrin, thiazoles, thiazolones, thiadiazoles, pyrazoles and pyrazolones

Thiocarbamoyl in synthesis of the absorbent bis-mono and dimethine cyanine dyes incorporating porphyrin, thiazoles, thiazolones, thiadiazoles, pyrazoles and pyrazolones

Miescher’s cheilitis: A case report with literature review

Melkersson–Rosenthal syndrome as an early manifestation of mixed connective tissue disease

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