Charcot-Marie-Tooth disease: peripartum management of two contrasting clinical cases

Greenwood, Jaime; Scott, Wendy E.

doi:10.1016/j.ijoa.2006.10.005

Cited by 18 publications

(10 citation statements)

References 19 publications

(11 reference statements)

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“…Pregnancy may also prove a consideration for CMT1A sufferers, with report in the literature that the condition may worsen during pregnancy, possibly associated with concurrent increased endoneural oedema or a physical exacerbation of diaphragmatic inefficiency associated with mechanical splinting from an expanding uterus (Greenwood and Scott, ).…”

Section: Wider Complicationsmentioning

confidence: 99%

“…Generally, the CMT1 grouping is described to manifest clinically in the first decade of life and to show the more severe motor and sensory signs when compared with CMT2 (Ropper et al, ). Unfortunately, the clinical literature does not always clarify which subtype of CMT is under consideration (Greenwood and Scott, ; Srivastava et al, ; Anens et al, ).…”

Section: Introductionmentioning

confidence: 99%

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Charcot‐Marie‐Tooth 1A: A narrative review with clinical and anatomical perspectives

McGrath

2015

Clinical Anatomy

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Charcot-Marie-Tooth 1A (CMT1A) is regarded as the most common hereditary peripheral neurodegenerative disorder. This narrative review highlights perspectives around the historically well-established and characteristic anatomical manifestations of CMT1A seen in the feet, legs and hands, in addition to a clinical diagnosis that may be confirmed by electrophysiology, genetic or molecular markers together with the presence of a typical family history. A less well-known perspective is the potential for systemic manifestations and wider complication. The condition is characterised by a progressive clinical picture with unmistakable anatomical and neurological features that have been described since the late 19th century. There remains no cure although supportive, rehabilitative, and surgical regimes may provide helpful management or amelioration of symptoms. Most recently, the emergence of a pleotherapeutic approach suggests distinct promise. Future research focused on a detailed elucidation of the underlying molecular mechanisms underpinning myelin and axonal function may eventually hold the key to successful treatment of CMT1A. Genetic modification would potentially present a cure. Clin. Anat. 29:547-554, 2016. © 2015 Wiley Periodicals, Inc.

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Section: Wider Complicationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Charcot‐Marie‐Tooth 1A: A narrative review with clinical and anatomical perspectives

McGrath

2015

Clinical Anatomy

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“…Patients with mild CMT may have a normal vaginal delivery with local or epidural anesthesia [127,128]. Patients with mild CMT may have a normal vaginal delivery with local or epidural anesthesia [127,128].…”

Section: Hereditary Neuropathiesmentioning

confidence: 99%

Neuromuscular Diseases in Pregnancy

Rezania

2011

Neurological Disorders and Pregnancy

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“…Nevertheless, also in obstetric practice, CNB should be administered with great caution in patients with spinal stenosis [40]. Case reports provide valuable information regarding the care of patients with rare conditions [41][42][43][44]45 ].…”

Section: Central Blockades In Patients With Neurological Diseasementioning

confidence: 99%