Characterization Techniques and Analysis

Jain, Neha; Jain, Prince K.; Singh, Rajan Kumar; Srivastava, Alka; Singh, Jai

doi:10.1002/9783527834884.ch3

Cited by 2 publications

(2 citation statements)

References 88 publications

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“…In digestive system, VZV infection may lead to gastritis [10], acute pancreatitis [11], or acute liver failure (ALF) [12]. VZV infection also play a role in severe autoimmune hepatitis because of immune cross reaction and autoimmune disorder [13] [14].…”

Section: Discussionmentioning

confidence: 99%

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Chen,

Wang,

Yan

2024

Preprint

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Background:Varicella (chicken pox), which caused by the varicella-zoster virus(VZV), is usually self-limiting and benign. However, VZV can lead to significant and serious complications, especially in immunocompromised patients or accompanied by other pathogens infection. HPS caused by varicella-zoster and influ B virus co-infection is rare. Case presentation:A 15-years-old boy was admitted to our hospital because of general rash, severe back and low back pain. CT scan revealed pneumonia in left upper lobe. Initial blood tests showed normal blood WBC and PLT, mild liver dysfunction, enhanced D-dimer and myocardial enzyme. However, after 4-days treatment of acyclovir, antibiotics, and analgesic therapy, his pain did not relieved and fever developed. At the same time, hyperferritinemia, abrupt reduction on blood WBC and PLT count were observed. Virus-associated hemophagocytic syndrome (VHAS)was confirmed.Then, intravenous drip dexamethasone(10mg/day) and gamma globulin(10mg/day) were administrated. He recovered completely at last. Conclusions:Disseminated Varicella which was accompanied by influenza B virus and bacteria infection is infrequent. Disseminated varicella may cause significant morbidity and even mortality in immunocompromised patients. Hemophilic syndrome induced by duel-virus and bacteria infection is limited and usually fetal.Anti-bacterial therapy, early identification of haemophilus syndrome and timely administration of glucocorticoids and gamma globulin are the key links of treatments.

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Section: Discussionmentioning

confidence: 99%

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Chen,

Wang,

Yan

2024

Preprint

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“…Organotin compounds find a lot of biocidal applications due to their toxicity against different microorganisms (Jain et al, 2004). Such compounds show potential biological applications such as antitumor and insecticidal activities.…”

Section: Compoundsmentioning

confidence: 99%

Biological Potential and Structure Activity Relationships in Organotin (IV) and Pd(II) Compounds

Hussain¹,

Sarfraz

2020

LGUJLS

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Organotin(IV) and palladium(II) complexes are mainly synthesized by treating a N,O or S donor ligand with an organotin halide and PdCl2, respectively. The structures of the complexes can be elucidated by various characterization techniques such as microanalysis (CHNS), FTIR spectroscopic analysis, UV-Visible spectroscopy, NMR (1H & 13C) and single crystal XRD. Organotin compounds are applied in numerous biocidal formulations as wood preservatives, surface disinfectants, antitumor agents, insecticides, marine antifouling paints, mollucides, miticides and fungicides. The biochemical activity is mainly affected by coordination number of tin, number and nature of the organic group bonded to tin and the chain length of an alkyl groups. Organotin(IV) dithiocarbamates are famous for their acaricidal, antifungal, tuberculostatic, antibacterial and anticarcinogenic activities. Cisplatin which is a famous Pt(II) drug, is successfully applied either alone or in various combinations to treat cancer. However, There is also a growing interest in the discovery of alternate drugs with palladium(II) because there are considerable similarities between the coordination chemistry of palladium(II) and platinum(II) compounds. However, the palladium complexes dissociate readily and form reactive species which could not reach their pharmacological targets. This drawback can be overcome by synthesizing Pd(II) complexes with chelating ligands such as dithiocarbamates. Pd(II) and Pt(II) compounds with bioactive ligands are of special interest due to their possibility of oral administration, lower toxicity and their ability to coordinate with DNA. Organotin(IV) derivatives possess strong antibacterial and antifungal potential while palladium(II) complexes are chiefly famous for their antitumor and anticancer activities. The nature of a metal coordinated to the ligand, has a decisive role in biological activities of both kinds of compounds.

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Characterization Techniques and Analysis

Cited by 2 publications

References 88 publications

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Biological Potential and Structure Activity Relationships in Organotin (IV) and Pd(II) Compounds

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