Characterization of rare earth aluminosilicate glasses

Marchi, Juliana; Morais, D.S.; Schneider, José Fabián; Bressiani, José Carlos; Bressiani, Ana Helena A.

doi:10.1016/j.jnoncrysol.2005.01.078

Cited by 114 publications

(78 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…limited amount of previous data on YAS glass, from computer simulation, [5] neutron, and X-ray diffraction, [6] NMR [7,8] and IR [9] spectroscopy, and none of these data concern the YAS17 composition. Also, much of this work has concentrated on the local structure around the silicon, aluminum, and oxygen ions; technical difficulties hinder NMR experiments that could address the yttrium local structure in this glass.…”

mentioning

confidence: 99%

Short‐Range Structure of Yttrium Alumino‐Silicate Glass for Cancer Radiotherapy: Car–Parrinello Molecular Dynamics Simulations

Christie

Tilocca

2010

Adv Eng Mater

View full text Add to dashboard Cite

Yttrium alumino-silicate (YAS) glass has an application in in situ cancer radiotherapy. [1] Conventional radiotherapy irradiates a tumor from a radiation source external to the body, which can cause substantial damage to the surrounding healthy tissue. On the other hand, internal, or in situ, radiotherapy implants a radiation source into the tumor or surrounding blood vessels, from where it can irradiate the tumor directly. This approach reduces the unnecessary damage to healthy tissues and the corresponding side effects of conventional radiotherapy. One method currently used for in situ radiotherapy is to inject a solution of YAS glass microspheres, in which the 90 Y isotope has been excited to a radioactive state, into the blood vessels supplying the tumor.The microspheres then reach and settle in the target tumor, which is hit by the localized radiation released from the yttrium source bound within the glass. The in situ method has been successful in treating deeply seated tumors associated with liver and kidney cancer, which are difficult to treat with conventional radiotherapy. [2,3] The key property of the glass for the success of this application is its chemical durability, defined as the inverse of the release rate of yttrium in the physiological environment. The glass should release as little radioactive 90 Y into the bloodstream as possible, because any yttrium so released would be transported to other healthy organs, which would be exposed to harmful doses of radiation. The half-life of 90 Y is 2.7 days, so the microspheres need only to be durable over a timescale of a few weeks. Several compositions of YAS glass were tested experimentally, and that with the highest durability, commonly used in in situ radiotherapy, had 17.1 mol% Y 2 O 3 , 18.9 mol% Al 2 O 3 , and 64.0 mol% SiO 2 (this composition is hereafter termed YAS17). [4] In order to optimize this kind of cancer treatment, it is critical to understand how yttrium is bound into the glass network and the factors which control its dissolution from the bulk glass into a surrounding fluid; however, the atomistic properties of YAS glass, particularly those relating to the local yttrium structure, are not well understood. There is only a We present Car-Parrinello molecular dynamics (CPMD) simulations of yttrium alumino-silicate (YAS) glass. Alumino-silicate glass microspheres are used as vectors of yttrium radioisotopes in cancer radiotherapy; understanding in detail how yttrium is bound within the glass network is important to control the unwanted release of radioactive yttrium in the bloodstream. Our simulations, focused on a specific composition relevant to practical applications, show that silicon and aluminum form a disordered glass network, where Si is mainly four-coordinated, whereas, Al is mainly four-and five-coordinated. Yttrium cations have a network-modifying role, disrupting the alumino-silicate network by breaking Si(Al)ÀO bonds and coordinating the resulting non-bridging oxygens (NBO). The local environment of yttrium in the glass turns ...

show abstract

mentioning

confidence: 99%

Short‐Range Structure of Yttrium Alumino‐Silicate Glass for Cancer Radiotherapy: Car–Parrinello Molecular Dynamics Simulations

Christie

Tilocca

2010

Adv Eng Mater

View full text Add to dashboard Cite

show abstract

“…These excellent properties are closely related to their special structure characteristics. The structural role of ions in aluminosilicate glasses is determined by their ionic radius and charge [9]. The ionic radius controls their coordination number in the glass structure.…”

Section: Introductionmentioning

confidence: 99%

STRUCTURE, GLASS STABILITY AND RHEOLOGICAL PROPERTIES OF Na₂O-CaO-Al₂O₃-SiO₂ GLASSES DOPED WITH Y₂O₃

Hou

2018

Ceramics - Silikaty

View full text Add to dashboard Cite

“…Among them, rare-earth aluminosilicate and calcium aluminosilicate glasses have been studied for many years due to their high elastic modulus and hardness, high refraction index, high thermal conductivity, high glass transition temperature, excellent optical properties and good corrosion resistance [4][5][6][7][8][9][10][11]. Moreover, they are known for their ability to accommodate high concentration of rare-earth active ions such as Nd 3+ or Er 3+ as well as their low phonon energy due to the aluminate network.…”

Section: Introductionmentioning

confidence: 99%

Directional solidification, thermo-mechanical and optical properties of (Mg_xCa_1-x)_3Al_2Si_3O_12 glasses doped with Nd^3+ ions

Sola¹,

Conejos²,

Mendívil³

et al. 2015

Opt. Express

View full text Add to dashboard Cite

Abstract:In this work glass rods of (Mg x Ca 1-x ) 3 Al 2 Si 3 O 12 (x = 0, 0.5 and 1) doped with 1 wt% Nd 2 O 3 were produced by the laser floating zone technique. Thermo-mechanical and spectroscopic properties have been evaluated. The three glass samples present good thermo-mechanical properties, with similar hardness, toughness and glass transition temperatures. The spectroscopic characterization shows spectral shifts in absorption and emission spectra. These spectral shifts together with JuddOfelt intensity parameters and ionic packing ratio have been used to investigate the local structure surrounding the Nd 3+ ions and the covalency of the Nd-O bond. All obtained results agree and confirm the higher covalency of the Nd-O bond in the Ca 3 Al 2 Si 3 O 12 glass. Kozankova, "Er-and Nd-doped yttrium aluminosilicate glasses: preparation and characterization," Opt. Mater. 33(12), 1872-1878 (2011 42(1-3), 189-196 (1980). -78-XX-95, 1978). 36. T. Izumitani, H. Toratani, and H. Kuroda, "Radiative and nonradiative properties of Neodymium doped silicate and phosphate glasses," J. Non-Cryst. Solids 47(1), 87-99 (1982). 37. W. F. Krupke, "Induced-emission cross sections in Neodymium laser glasses," IEEE J. Quantum Electron. QE-10(4), 450-457 (1974). 38. M. J. Weber, D. C. Ziegler, and C. A. Angell, "Tailoring stimulated emission cross sections of Nd 3+ laser glass: observation of large cross sections for BiCl 3 glasses," J. Appl. Phys. 53(6), 4344-4350 (1982 66-78 (1998). 43. R. D. Shannon, "Revised effective ionic radii and systematic studies of interatomic distances in halides and chalcogenides," Acta Crystallogr. A 32(5), 751-767 (1976). 44. L. A. Riesberg and M. J. Weber, "Relaxation phenomena in rare-earth luminescence," Prog. Optics 14, 89-159 (1975 5799-5811 (1978).

show abstract

Characterization of rare earth aluminosilicate glasses

Cited by 114 publications

References 15 publications

Short‐Range Structure of Yttrium Alumino‐Silicate Glass for Cancer Radiotherapy: Car–Parrinello Molecular Dynamics Simulations

Short‐Range Structure of Yttrium Alumino‐Silicate Glass for Cancer Radiotherapy: Car–Parrinello Molecular Dynamics Simulations

STRUCTURE, GLASS STABILITY AND RHEOLOGICAL PROPERTIES OF Na₂O-CaO-Al₂O₃-SiO₂ GLASSES DOPED WITH Y₂O₃

Directional solidification, thermo-mechanical and optical properties of (Mg_xCa_1-x)_3Al_2Si_3O_12 glasses doped with Nd^3+ ions

Contact Info

Product

Resources

About