“…Polyglycolic acid (PGA) has proven to be one of the most successful scaffolds for cartilage regeneration (Cui et al, 2009;Frenkel, Di, 2004;Heath, Magari, 1996). Cartilage engineered with the PGA scaffold has structure and composition similar to the native tissue, as demonstrated by histological analysis and cartilage specific matrices (Aufderheide, Athanasiou, 2005;Moran et al, 2003;Yan et al, 2009). However, the most widely used form of PGA material in cartilage engineering is unwoven fiber mesh, which is difficult to be initially prepared into a complicated 3D structure and would most likely fail to maintain its original architecture during subsequent in vitro chondrogenesis due to insufficient mechanical support (Gunatillake, Adhikari, 2003;Kim, Mooney, 1998;Moran et al, 2003).…”