Characterization of multidrug resistant Salmonella recovered from diseased animals

Production biomolecule with inhibitory activity against Gram-negative bacteria isolated from faeces of broilers and swine

“…The resistance to ampicillin, cefalotin, cefatoxime, cefoxitin and tigecycline was detected in Pseudomonas aeruginosa no resistance was observed in E. coli for the same drugs. Zhao et al (2007) characterized the multidrug resistance to antibiotics in 308 Salmonella stain isolated from the animal diagnostic samples and found the highest rate of resistance for the isolates from swine (92%), followed by turkey (91%), cattle (77%), chicken (68%) and horse (20%). For amikacin (≥ 32 µg/mL), there was no resistance among the isolates from chickens and only 1% for the swine isolates.…”

Antimicrobial Resistance in Salmonella spp. isolated from cattle gallbladder slaughtered in the south of the state of Rio de Janeiro

“…According to Davis et al (2007), the AmpC beta-lactamase gene (cmy-2) is responsible for encoding resistance to cephalosporin spectrum in Salmonella spp. Zhao et al (2007), analyzed 129 cattle and found that 66% of Salmonella strains were resistant to ampicillin. Davis et al (2007) reported that between 2001 and 2004, 79.6% of Salmonella Dublin isolates from cattle were resistant to ampicillin and 32.7% to trimethoprimsulfa.…”

“…The indiscriminate use of antimicrobials in livestock directly contributes to the development of Salmonella MAR. This fact has alarming consequences for public health because it reduces the number of therapy options in cases of invasive infection in animals and humans (Zhao et al, 2007).…”

“…Cattle may constitute an important reservoir for human infections (Wray & Davies, 2000). This genus exhibits resistance to many antibiotics and could become a problem in both human and veterinary medicine (Zhao et al, 2007). In cattle populations where antimicrobials are used, Salmonella species are under high selection pressure, and generic strains begin to present Multiple Antibiotic Resistance (MAR) (Defrancesco et al, 2004).…”

The Importance of Mobile Genetic Elements in the Evolution of Salmonella: Pathogenesis, Antibiotic Resistance and Host Adaptation

“…The association of integrons with mobile elements and resistance genes has led to their rapid dispersal among various bacteria found in environments exposed to antibiotics (MartinezFreijo et al, 1999;White et al, 2001;Boucher et al, 2007). (Lindstedt et al, 2003;Antunes et al, 2006;Su et al, 2006;Molla et al, 2007;Zhao et al, 2007). More surprising was that these integrons were also found in different species of the Gram-positive genera Staphylococcus isolated in China (Xu et al, 2008), providing evidence of the successful spread of these integrons around the world and across bacterial phyla ).…”