Characterization of modified Chitosan thin film

Sivaselvi, K.; Ghosh, Pijush

doi:10.1016/j.matpr.2017.01.043

Cited by 9 publications

(3 citation statements)

References 10 publications

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“…From stress-strain curves ( Figure 10 ), the tensile strength, Young’s modulus, and elongation at break for pure CS, CS/Cel, CS/HH and CS/Cur at different concentrations were calculated and presented in Figure 11 . Pure CS film shows low tensile strength, which is due to its low water resistance properties, and this gives chitosan its poor mechanical properties [ 64 , 65 , 66 , 67 ]. In order to improve these properties, CS films were blended with natural materials because chitosan films with higher tensile strength and reasonable elongation at break values have a higher potential in medical and other applications [ 68 , 69 ].…”

Section: Resultsmentioning

confidence: 99%

Improvement of Chitosan Films Properties by Blending with Cellulose, Honey and Curcumin

Madian,

El-Ashmanty,

Abdel-Rahim

2023

Polymers

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Chitosan is a natural biopolymer that can be used in biomedical applications, tissue engineering, and wound dressing because of its biodegradability, biocompatibility, and antibacterial activity. The blending of chitosan films with natural biomaterials such as cellulose, honey, and curcumin was studied at different concentrations in order to improve their physical properties. Fourier transform infrared (FTIR) spectroscopy, mechanical tensile properties, X-ray diffraction (XRD), antibacterial effects, and scanning electron microscopy (SEM) were studied for all blended films. The XRD, FTIR, and mechanical results showed that films blended with curcumin were more rigid and compatible and had higher antibacterial effects than other blended films. In addition, XRD and SEM showed that blending chitosan films with curcumin decreases the crystallinity of the chitosan matrix compared to cellulose and honey blending films due to increased intermolecular hydrogen bonding, which reduces the close packing of the CS matrix.

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Section: Resultsmentioning

confidence: 99%

Improvement of Chitosan Films Properties by Blending with Cellulose, Honey and Curcumin

Madian,

El-Ashmanty,

Abdel-Rahim

2023

Polymers

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“…Chitosan solutions (1% w/v) in 0.05 M acetic acid were prepared. [18]. When dissolved in acetic acid, chitosan becomes a polycation by the chemical reaction of protonation of chitosan in acetic acid and polycation formation.…”

Section: Polyelectrolyte Solutionsmentioning

confidence: 99%

Biosensors Based on Stanniocalcin-1 Protein Antibodies Thin Films for Prostate Cancer Diagnosis

Ferreira,

Ribeiro,

Canário

et al. 2023

Biosensors

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Prostate cancer is one of the most prevalent tumors in men, accounting for about 7.3% of cancer deaths. Although there are several strategies for diagnosing prostate cancer, these are only accurate when the tumor is already at a very advanced stage, so early diagnosis is essential. Stanniocalcin 1 (STC1) is a secreted glycoprotein, which has been suggested as a tumor marker as its increased expression is associated with the development and/or progression of different types of malignant tumors. In this work, an electronic tongue (ET) prototype, based on a set of four sensors prepared from thin films that included STC1 antibodies for detecting prostate cancer, was developed. In the preparation of the thin films, polyelectrolytes of polyallylamine hydrochloride, polystyrene sulfonate of sodium and polyethyleneimine, and the biomolecules chitosan, protein A, and STC1 antibody were used. These films were deposited on quartz lamellae and on solid supports using layer-on-layer and self-assembly techniques. The deposition of the films was analyzed by ultraviolet-visible spectroscopy, and the detection of STC1 in aqueous solutions of PBS was analyzed by impedance spectroscopy. The impedance data were statistically analyzed using principal component analysis. The ETs formed by the four sensors and the three best sensors could detect the antigen at concentrations in the range from 5 × 10−11 to 5 × 10−4 M. They showed a linear dependence with the logarithm of the antigen concentration and a sensitivity of 5371 ± 820 and 4863 ± 634 per decade of concentration, respectively. Finally, the results allow us to conclude that this prototype can advance to the calibration phase with patient samples.

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“…9 represents the structural formula of chitosan. The advantage of using chitosan in the fabrication of thin film includes good mechanical strength, low cost, hydrophilicity and hydrophobicity [47,104,105] and being biodegradable [106][107][108]. The existence of piezoelectricity behaviour in chitosan marks good potential in using it as a sensing material on a piezoelectric sensor device [109].…”

Section: Chitosan Based Sensormentioning

confidence: 99%

Advanced vapour sensing materials: Existing and latent to acoustic wave sensors for VOCs detection as the potential exhaled breath biomarkers for lung cancer

Hekiem

Ralib

Hattar

et al. 2021

Sensors and Actuators A: Physical

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Lung cancer is the leading cause of death worldwide and has a significant impact on public health across society. Among all types of cancer, lung cancer is typically silent and it is commonly diagnosed at a later stage where treatment is rarely achievable. There is an urgent need for the development of the early diagnosis of lung cancer for an improved survival rate. Preliminary research shows that lung cancer is accompanied by increased oxidative stress which generates volatile organic compounds (VOCs). Hence, breath analysis offers the most promising solution for the early diagnosis of lung cancer as it is noninvasive and radiation free. Potential VOCs biomarkers in exhaled breath associated with oxidative stress and lipid peroxidation have been discussed to provide a quick approach to the diagnosis of lung cancer. Although gas chromatography-mass spectroscopy (GC-MS) able to analyze the VOCs biomarker, it is bulky, high cost, required expertise to handle and consumes a lot of time. Hence, the sensor-based technique provides the solution to overcome the limitation. Recently, acoustic wave sensors such as quartz crystal microbalance (QCM) and surface acoustic wave sensors (SAW) have been used to identify the presence of VOCs in various applications. This is due to its high selectivity, good reproducibility, and fast response sensing materials. The selection of vapour sensing materials plays a crucial role in developing a highly sensitive and selective and fast response acoustic wave sensors. For this purpose, various types of sensing layers from metal oxides, polymers, biopolymers and composites have been studied. We present a critical review of advanced vapour sensing materials that are primarily used in acoustic wave sensors in identifying the presence of various VOCs. Criteria to evaluate the performance of the acoustic wave sensors such as resonance frequency and sensitivity are also discussed.

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Characterization of modified Chitosan thin film

Cited by 9 publications

References 10 publications

Improvement of Chitosan Films Properties by Blending with Cellulose, Honey and Curcumin

Improvement of Chitosan Films Properties by Blending with Cellulose, Honey and Curcumin

Biosensors Based on Stanniocalcin-1 Protein Antibodies Thin Films for Prostate Cancer Diagnosis

Advanced vapour sensing materials: Existing and latent to acoustic wave sensors for VOCs detection as the potential exhaled breath biomarkers for lung cancer

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