Characterization of extended-spectrum β-lactamases in Salmonella spp. at a tertiary hospital in Durban, South Africa

Characterisation of extended-spectrum β-lactamases among Klebsiella pneumoniae isolates causing bacteraemia and urinary tract infection in Mozambique

“…Although ESBLs have been previously reported in sub-Saharan Africa [5][6][7][27][28][29][30], the report of ESBLs in a rural hospital with limited access to third-generation cephalosporins, such as in Manhiça, Mozambique, is relevant, suggesting again the coselection of antibiotic resistance genes. Despite access to thirdgeneration cephalosporins being limited in this community, a high prevalence of b-lactamase genes, such as bla TEM-like and bla OXA-like , has been reported in Shigella and Salmonella isolates in previous studies, reflecting of the high use of ampicillin in the area [23].…”

“…The reported prevalence of ESBLs is high compared with that reported in neighbouring countries such as Tanzania [27] and South Africa [5]. In another sub-Saharan country (Ethiopia), a high level of ESBL-producers (36%; 46% among inpatients and 33% among outpatients) was reported among E. coli strains from different samples (urine, sputum, stool, wound swabs) [28].…”

“…Knowledge of the prevalence and characterisation of ESBLs is critical for defining local empirical strategies for the treatment of infections [4]. Although in Africa the presence of ESBLs has increasingly been reported [5][6][7], data in Mozambique remain limited.…”

Antibiotic resistance patterns and beta-lactamase identification in Escherichia coli isolated from young children in rural Limpopo Province, South Africa: The MAL-ED cohort

“…[21] Since then, other CTX-M types have been found in SA, including CTX-M-14, CTX-M-15 and CTX-M-37. [22][23][24][25] The WHO reports that in the African Region there are insufficient data concerning antibiotic resistance, [26] so additional reports such as this are important in this regard. The data presented are limited to the MAL-ED SA Dzimauli community study site of Limpopo Province.…”

Case Report of Pediatric Gastroenteritis Due to CTX-M-15 Extended-Spectrum β-Lactamase-Producing Salmonella enterica Serotype Enteritidis

“…CTX-M-15 ESBL was first reported in E. coli, K. pneumoniae, and Enterobacter aerogenes isolates in [2000][2001] in India [16]. CTX-M-15 has been detected in Salmonella isolates from various countries, including France, Kuwait, the United Arab Emirates, South Africa, Senegal, and Algeria [2,13,15,17]. In this report, we describe a pediatric S. enterica serotype Enteritidis isolate that harbored the ESBL CTX-M-15, which is the first time this enzyme has been found in Korea.…”