Case Report of Pediatric Gastroenteritis Due to CTX-M-15 Extended-Spectrum β-Lactamase-Producing Salmonella enterica Serotype Enteritidis

Lee, Kon Hee; Song, Wonkeun; Jeong, Seok Hoon; Choi, Kwon‐Young; Yoon, Hye Sun; Park, Min Jeong

doi:10.3343/kjlm.2009.29.5.461

Cited by 14 publications

(13 citation statements)

References 18 publications

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“…In Korea, a few isolates of TEM-52, CTX-M-14, and CTX-M-15 ESBL-producing Salmonella spp. were detected, of which CTX-M-15 was the most common, followed by CTX-M-14 (13,19,29,30). In the present study, 7 CTX-M-producing Salmonella isolates were identified.…”

Section: Discussionmentioning

confidence: 82%

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Serotyping and Antimicrobial Susceptibility of Salmonella spp.: Nationwide Multicenter Study in Korea

et al. 2013

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SUMMARY:The study aimed to investigate the prevalence of various serotypes and extended-spectrum b-lactamase-producing features of Salmonella strains and to determine the antimicrobial susceptibility of 256 Salmonella strains other than Salmonella serotype Typhi, which were isolated at 12 university hospitals in Korea. We identified 46 serotypes of Salmonella spp. Serogroup D was the most common (39.5z), followed by B (32.4z), C (22.7z), E (2.7z), A (2.3z), and G (0.4z). The three most common Salmonella serotypes were Enteritidis (36.3z), Typhimurium (16.8z), and Infantis (7.8z). Six strains that belonged to serotype Paratyphi A and nine that belonged to serotype Paratyphi B were also detected. The 256 Salmonella strains had a 38.7z rate of resistance to ampicillin, 23.0z to chloramphenicol, 8.2z to cefotaxime, 8.6z to ceftriaxone, and 6.3z to trimethoprim-sulfamethoxazole. The antimicrobial resistance rates of Salmonella serogroups B and D were higher than those of the other serogroups. Seven isolates carried bla CTX-M : four CTX-M-15, two CTX-M-14, and one CTX-M-3.

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Section: Discussionmentioning

confidence: 82%

“…(11). However, there have also been reports of increased resistance to these agents, including bacterial production of extendedspectrum b-lactamases (ESBLs) (12,13).…”

Section: Introductionmentioning

confidence: 99%

Serotyping and Antimicrobial Susceptibility of Salmonella spp.: Nationwide Multicenter Study in Korea

et al. 2013

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“…Since bla CTX-M-15 was first identified in Enterobacteriaceae in 2003 in South Korea (18), bla CTX-M genes have been increasingly reported in Enterobacteriaceae either singly or in combination with other resistance determinants (21,29). However, until recently, reports on CTX-M-type ␤-lactamase in Salmonella were limited to human isolates, particularly those causing salmonellosis in pediatric patients (19,32). Thus, to our knowledge, cefotaximase has never been reported in Salmonella strains of animal origin from South Korea.…”

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confidence: 99%

Emergence of Extended-Spectrum β-Lactamase (CTX-M-15 and CTX-M-14)-Producing Nontyphoid Salmonella with Reduced Susceptibility to Ciprofloxacin among Food Animals and Humans in Korea

et al. 2011

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Twenty of 1,279 nontyphoid Salmonella strains isolated from food animals and humans produced CTX-Mtype extended-spectrum ␤-lactamase. All expressed CTX-M-15, except two which coexpressed CTX-M-14 and TEM-1. Insertion sequence ISEcp1 was identified upstream of bla CTX-M genes. The bla CTX-M-15 and bla CTX-M-14 genes were disseminated by large conjugative IncFIIs and IncI1-I␥ plasmids, respectively.

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“…Chloramphenicol, ampicillin, and trimethoprim-sulfametoxazole could be employed for treating patients with salmonellosis. However, due to increasing resistance to these drugs, fluroquinolones and third generation cephalosporins have now been frequently selected (20,24,40,41) . The high resistance rate to nalidixic acid corroborates data reported by other researchers (29,39) and should be considered a predictable result since the drug is frequently used in Brazil for treating patients diagnosed with inflammatory diarrhea.…”

Section: Discussionmentioning

confidence: 99%

Acute diarrhea associated with Salmonella enterica in Belo Horizonte-MG: prevalence and characterization of isolates

Sousa

Mendes²,

Penna³

et al. 2013

J. Bras. Patol. Med. Lab.

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Introduction: Acute infectious diarrhea is still regarded as a public health problem associated with a wide range of etiologic agents, from which Salmonella enterica is particularly worth mentioning inasmuch as it is a major cause of inflammatory diarrhea in both developed and developing countries. Objective: To assess the distribution of S. enterica among children with acute diarrhea in Belo Horizonte and to characterize bacterium isolates. Material and methods: The study group comprised a total of 157 children from low socioeconomic background. Stool samples were collected for leukocyte analysis and Salmonella bacterial culture. The isolates were serotyped and evaluated as to antimicrobial susceptibility profile, extended-spectrum β-lactamases (ESBL) production, and presence of virulence markers (invA, iroB, and spvC). Results: A total of 5/3.2% children were infected by S. enterica, 3/60% by S. enterica Typhimurium, 1/20% by S. enterica Enteritidis and 1/20% S. enterica subsp. enterica serotype 8.20:z4,z23:-. Fecal leucocytes were detected in two out of five fecal specimens positive for S. enterica. Isolates from three children were resistant to nalidixic acid, nalidixic acid + chloramphenicol, and nalidixic acid + chloramphenicol + ampicillin. ESBL production was not detected. All samples presented invA and iroB genes. spvC marker was observed in isolates from two children infected by S. Typhimurium and S. Enteritidis. Conclusion:The results demonstrate that S. enterica infection is uncommon among children from our region. Furthermore, they indicate the need for periodic monitoring of bacterial antimicrobial susceptibility profile in order to establish suitable antimicrobial therapy when required.

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Case Report of Pediatric Gastroenteritis Due to CTX-M-15 Extended-Spectrum β-Lactamase-Producing Salmonella enterica Serotype Enteritidis

Cited by 14 publications

References 18 publications

Serotyping and Antimicrobial Susceptibility of <i>Salmonella</i> spp.: Nationwide Multicenter Study in Korea

Serotyping and Antimicrobial Susceptibility of <i>Salmonella</i> spp.: Nationwide Multicenter Study in Korea

Emergence of Extended-Spectrum β-Lactamase (CTX-M-15 and CTX-M-14)-Producing Nontyphoid Salmonella with Reduced Susceptibility to Ciprofloxacin among Food Animals and Humans in Korea

Acute diarrhea associated with Salmonella enterica in Belo Horizonte-MG: prevalence and characterization of isolates

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