Characterization of broadband fiber optic line detectors for photoacoustic tomography

Berer, Thomas; Veres, István A.; Grün, Hubert; Bauer-Marschallinger, Johannes; Felbermayer, Karoline; Burgholzer, Peter

doi:10.1002/jbio.201100110

Cited by 42 publications

(46 citation statements)

References 44 publications

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“…Fiber optic ultrasound detection can be treated as a problem of the scattering of the obliquely incident acoustic wave from a solid cylinder with infinite length 31,32 . The scattered wave establishes a non-uniform stress/strain profile over the optical fiber and induces changes in refractive index as well as fiber elongation.…”

Section: Resultsmentioning

confidence: 99%

Fiber laser based ultrasound sensor for photoacoustic imaging

Liang

Wang

Jin

et al. 2017

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)

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Photoacoustic imaging, especially for intravascular and endoscopic applications, requires ultrasound probes with miniature size and high sensitivity. In this paper, we present a new photoacoustic sensor based on a small-sized fiber laser. Incident ultrasound waves exert pressures on the optical fiber laser and induce harmonic vibrations of the fiber, which is detected by the frequency shift of the beating signal between the two orthogonal polarization modes in the fiber laser. This ultrasound sensor presents a noise-equivalent pressure of 40 Pa over a 50-MHz bandwidth. We demonstrate this new ultrasound sensor on an optical-resolution photoacoustic microscope. The axial and lateral resolutions are 48 μm and 3.3 μm. The field of view is up to 1.57 mm 2 . The sensor exhibits strong resistance to environmental perturbations, such as temperature changes, due to common-mode cancellation between the two orthogonal modes. The present fiber laser ultrasound sensor offers a new tool for alloptical photoacoustic imaging.Photoacoustic tomography (PAT) is a phenomenally growing imaging technology which offers high-contrast, high-resolution and non-invasive imaging in deep tissue 1,2 . PAT has received great interests due to promising applications in disease diagnoses and life science researches [3][4][5][6][7] . PAT detects optically induced ultrasound signals to form three-dimensional images [8][9][10] . Further development of PAT demands high-performance ultrasound sensors with high sensitivity, small size, broad bandwidth and great stability. Specifically, intravascular and endoscopic photoacoustic imaging requires ultrasound probes with miniature sizes and high sensitivity 11 . However, piezoelectric detectors are limited by the tradeoff between sensor size and sensitivity. For instance, a polyvinylidene (PVDF) needle hydrophone with a diameter of 75 μ m presents much lower sensitivity than that with ordinary size, with a noise-equivalent pressure (NEP) of 6 kPa over 100 MHz 12 . In recent years, a number of photonic ultrasound sensors have been developed with outstanding sensitivity, broad bandwidth and compact size [13][14][15] , optical transparency, and even possibility for non-contact measurement [16][17][18] . Photonic ultrasound sensors usually employ high-finesse optical resonators to detect incident elastic waves. For instance, a polymer micro-ring resonator (60 μ m in diameter) has presented 105 Pa NEP over a bandwidth of 350 MHz 19,20 . Ultrasound transducers based on planar Fabry-Perot (FP) cavity have reached a NEP of 210 Pa over 20 MHz bandwidth 21 . A reflection-mode PAM system using FP etalons for optical ultrasound detection has been developed 22,23 , which has achieved a NEP of 80 Pa and bandwidth of 18 MHz. The high sensitivity, however, raises its susceptibility to environmental disturbances. Complicated stabilization strategies have to be employed to enhance the resistance to external perturbations.Advanced fiber laser techniques have been developed for optical communication, sensing, measurement, ...

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Section: Resultsmentioning

confidence: 99%

Fiber laser based ultrasound sensor for photoacoustic imaging

Liang

Wang

Jin

et al. 2017

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)

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“…Thus the phase changes and the resulting demodulated signals are larger. This was shown experimentally in [14] and theoretically in [15]. As POF a perfluorinated graded-index polymer optical fiber (GI-POF) was used which exhibits lower optical attenuation at the used wavelength of 1550 nm compared to a standard POF.…”

Section: B Optical Detectionmentioning

confidence: 96%

Dual mode photoacoustic/acoustic microscopy with optical generation and detection

Berer

Grün

Bauer-Marschallinger

et al. 2012

2012 IEEE International Ultrasonics Symposium

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We present a dual mode scanning microscope which provides simultaneously ultrasonic and photoacoustic images. Short laser pulses are used to excite photoacoustic waves in a sample and to generate focused acoustic waves on a conical target. Ultrasound generation for pulse-echo mode is done by illuminating an acoustic axicon, resulting in quasi diffraction free acoustic pulses. An optical ring-shaped detector measures photoacoustic signals and backscattered acoustic waves. Due to the annular shape of the detector mainly acoustic waves coming from the symmetry axis, i.e. A-scans, are acquired; thus no reconstruction algorithm is needed. By reason of the transducers geometry, the setup is operated in backward mode. The annular detector is realized by a polymer optical fiber bent into a ring shape, being part of a fiber optic Mach-Zehnder interferometer. The annular detector mainly detects signals on the symmetry axis; however, also off-axis signals are detected. Reduction of the imaging artifacts is demonstrated on simulated data with a kspace algorithm taking the geometry of the problem into account. Furthermore, we present measurements on phantom samples.

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“…Optical detectors utilizing interferometric techniques [43,[53][54][55], oblique-incidence reflectance [56], microring resonators [57], fiber-optic lines [58,59], and laser beam deflection [60,61] can also be applied to detect ultrawideband optoacoustic signals. In addition to ultrawideband sensitivity, there are three main advantages of optical detection: (1) possibility for remote (noncontact) optoacoustic detection; (2) small finite size of the virtual detectors enabled by the tightly focused laser beam, which in turn yields high lateral resolution; and (3) possibility of avoiding acoustic diffraction and wavefront distortion in the handheld probes operating in the backward mode [62].…”

Section: Optoacoustic Transducersmentioning

confidence: 99%

Near-Infrared Fluorescence Imaging and Spectroscopy in Random Media and Tissues

2014

Biomedical Photonics Handbook

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Characterization of broadband fiber optic line detectors for photoacoustic tomography

Cited by 42 publications

References 44 publications

Fiber laser based ultrasound sensor for photoacoustic imaging

Fiber laser based ultrasound sensor for photoacoustic imaging

Dual mode photoacoustic/acoustic microscopy with optical generation and detection

Near-Infrared Fluorescence Imaging and Spectroscopy in Random Media and Tissues

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