Characterization of biodegradable polymers irradiated with swift heavy ions

Salguero, Noelia; Grosso, M.F. del; Durán, Hebe; Peruzzo, Pablo Jose; Amalvy, Javier Ignacio; Arbeitman, Claudia R.; Bermúdez, G. Garcı́a

doi:10.1016/j.nimb.2011.07.035

Cited by 8 publications

(11 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After this period and in these conditions, the authors verified that the contact angle of the PHB decreased by about 10 % because the fact of hydrolysis generating hydrophilic chains and, thus, the material was able to absorb higher amount of water. This study also showed that the PHB lost little mass during the incubation period, a value that was between 1 % and 1.5 % [16]. This small percentage may be explained due to micro porosity of polymer that reduced the rate of water adsorption into the polymeric matrix and at the same time represented a barrier to the flow of the products of degradation to the solution.…”

Section: Abiotic Degradationmentioning

confidence: 63%

“…The polyesters, as the PHB, are more susceptible to hydrolysis due to the presence of the group -COO - [3], and can have their ester connections cleaved through the hydrolytic process, under natural conditions [15]. SALGUERO et al [16] submitted the PHB to a hydrolytic degradation in vitro, in a saline solution of phosphate with pH 7, at a temperature of 37 • C during 40 days. After this period and in these conditions, the authors verified that the contact angle of the PHB decreased by about 10 % because the fact of hydrolysis generating hydrophilic chains and, thus, the material was able to absorb higher amount of water.…”

Section: Abiotic Degradationmentioning

confidence: 99%

See 1 more Smart Citation

From obtaining to degradation of PHB: A literature review. Part II

et al. 2018

View full text Add to dashboard Cite

In our previous review (Part I -Material Properties), the chemical, physical and morphological properties, applications and mechanisms of obtaining poly (3-hydroxybutyrate) were discussed. PHB is a biologically based polymer that presents itself as an ecological option due to its characteristic degradation before environmental factors and due to the action of microorganisms such as algae, fungi and bacteria. In this second review, aspects related to the types of degradation to which this polymer is subjected and the necessary conditions for its degradation are addressed. Among these mechanisms are thermo-degradation, thermo-mechanical degradation, abiotic degradation, photo degradation and biodegradation. It is understood that the degradation of PHB can be seen as an advantageous feature of this material. This review complements the previous one and uses the same terminology. Universidad EAFIT 207|From Obtaining to Degradation of PHB: A Literature Review. Part II Keywords: Biopolymers; degradation of PHB; poly(hydroxyalkanoate) (PHA); poly(3-hydroxybutyrate) (PHB).De la obtención a la degradación de PHB: Una revisión de la literatura. Parte II ResumenEn nuestra revisión anterior (parte I -propiedades del material), se discutieron las propiedades químicas, físicas y morfológicas, aplicaciones y mecanismos de obtención del poli (3-hidroxibutirato). El PHB es un polí-mero de base biológica que se presenta como una opción ecológica debido a su característica de degradación en la presencia de factores ambientales y debido a la acción de microorganismos como algas, hongos y bacterias. En esta segunda revisión se abordan aspectos relacionados con los tipos de degradación a los que este polímero está sujeto y las condiciones necesarias para su degradación. Entre estos mecanismos están la degradación térmica, la degradación termomecánica, la degradación abiótica, la foto de degradación y la biodegradación. Se percibe que la degradación del PHB puede ser vista como una característica ventajosa de este material. Esta revisión complementa la anterior y utiliza la misma terminología.Palabras clave: Biopolímeros; degradación de PHB; poli(hidroxialcanoato)(PHA); poli(hidroxibutirato)(PHB).

show abstract

Section: Abiotic Degradationmentioning

confidence: 63%

Section: Abiotic Degradationmentioning

confidence: 99%

From obtaining to degradation of PHB: A literature review. Part II

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The effect of the enzyme on the corresponding erosion process was therefore observed for longer durations as pointed out by the weight loss and morphological aspect of the PHBHV/OLE fibers after 8 weeks. Salguero et al assessed the PHB degradation in vitro, using the same protocol performed in abiotic conditions, namely PBS at pH 7 and at 37 °C for 40 days [ 38 ]. After this period, their results showed a limited PHB mass loss, ranging in 1.0–1.5%.…”

Section: Discussionmentioning

confidence: 99%

Electrospun Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate)/Olive Leaf Extract Fiber Mesh as Prospective Bio-Based Scaffold for Wound Healing

et al. 2022

View full text Add to dashboard Cite

Polyhydroxyalkanoates (PHAs) are a family of biopolyesters synthesized by various microorganisms. Due to their biocompatibility and biodegradation, PHAs have been proposed for biomedical applications, including tissue engineering scaffolds. Olive leaf extract (OLE) can be obtained from agri-food biowaste and is a source of polyphenols with remarkable antioxidant properties. This study aimed at incorporating OLE inside poly(hydroxybutyrate-co-hydroxyvalerate) (PHBHV) fibers via electrospinning to obtain bioactive bio-based blends that are useful in wound healing. PHBHV/OLE electrospun fibers with a size of 1.29 ± 0.34 µm were obtained. Fourier transform infrared chemical analysis showed a uniform surface distribution of hydrophilic -OH groups, confirming the presence of OLE in the electrospun fibers. The main OLE phenols were released from the fibers within 6 days. The biodegradation of the scaffolds in phosphate buffered saline was investigated, demonstrating an adequate stability in the presence of metalloproteinase 9 (MMP-9), an enzyme produced in chronic wounds. The scaffolds were preliminarily tested in vitro with HFFF2 fibroblasts and HaCaT keratinocytes, suggesting adequate cytocompatibility. PHBHV/OLE fiber meshes hold promising features for wound healing, including the treatment of ulcers, due to the long period of durability in an inflamed tissue environment and adequate cytocompatibility.

show abstract

“…However, a very low polar component inhibits osteoblast adhesion 18) . Consequently, on a hydrophilic material surface, good cellular adhesion and spreading are observed 19,20) . with prolonged culture times, osteoblasts on the LRF Ti surface maintain adhesion similar to those on the CP Ti surface.…”

Section: Morphological Observationmentioning

confidence: 99%

Biocompatibility Evaluation of Titanium Produced by Laser Rapid Forming

Zhu

Tian

Xiao

et al. 2016

J. Hard Tissue Biology.

View full text Add to dashboard Cite

The study aims to evaluate the biocompatibility of titanium produced by laser rapid forming. Ten laser rapid forming titanium (LRF Ti) discs and ten commercially pure titanium (CP Ti) discs were prepared; CP Ti discs were used as controls. Total surface energy was calculated by measuring the contact angle of the metallic surface, and calvaria of newborn Sprague-Dawley rats were used for the primary culture of osteoblasts to study adhesion, spreading, and proliferation of osteoblasts on the metallic surface. The dispersive component, polar component, and total surface energy of LRF Ti discs were larger than those of controls (P < 0.05). After 10 d of osteoblast culture, the cellular adhesive percentage and alkaline phosphatase activity of the LRF Ti group was significantly higher than those of controls (P < 0.05). With increasing culture time, more cells gradually attached to the LRF Ti metallic surface, which caused changes in cellular morphology. This study demonstrates that LRF Ti is highly compatible with bone similar to CP Ti and meets the biocompatibility requirements for implant materials.

show abstract

Characterization of biodegradable polymers irradiated with swift heavy ions

Cited by 8 publications

References 11 publications

From obtaining to degradation of PHB: A literature review. Part II

From obtaining to degradation of PHB: A literature review. Part II

Electrospun Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate)/Olive Leaf Extract Fiber Mesh as Prospective Bio-Based Scaffold for Wound Healing

Biocompatibility Evaluation of Titanium Produced by Laser Rapid Forming

Contact Info

Product

Resources

About