Characterization of airway nitric oxide in allergic rhinitis: The effect of intranasal administration of <scp>l</scp>‐NAME

Palm, Jörgen; Alving, Kjell; Lundberg, Jon O.

doi:10.1034/j.1398-9995.2003.00098.x

Cited by 48 publications

(40 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The simplest and most used method for measuring nasal NO is based on direct aspiration of nasal air from the nasal cavity, using the intrinsic flow of the NO analyser [54,[111][112][113]. Typically, the sampling probe is connected to a nasal olive, which is gently introduced into one nostril.…”

Section: Methods For Nasal No Measurementmentioning

confidence: 99%

“…Conversely, other studies showed no differences between rhinitic patients and control subjects. For instance, in patients with allergic rhinitis, Palm et al [54] revealed no change in nasal NO levels, whereas orally exhaled NO resulted to be increased. Also other groups failed to find an evident increase in nasal NO in seasonal rhinitis, during as well as out of the pollen season [47,50].…”

Section: Allergic Rhinitismentioning

confidence: 99%

See 1 more Smart Citation

Nitric oxide in upper airways inflammatory diseases

2007

View full text Add to dashboard Cite

In the human respiratory tract, the main production sites of exhaled nitric oxide (NO) are the nose and paranasal sinuses. In the upper airways, NO has been suggested to be involved at different levels with regulatory, protective, defensive or deleterious effects. Therefore, we review some aspects of the origin, metabolism, and functions of NO in the upper airways, together with the role of NO in some upper airways inflammatory diseases. Furthermore, we discuss the recent improvements in nasal NO measurements, which may be useful to better characterize the involvement of the NO produced by nose and paranasal sinuses in upper airways inflammatory diseases such as allergic rhinitis, nasal polyposis, sinusitis, primary ciliary dyskinesia, and cystic fibrosis.

show abstract

Section: Methods For Nasal No Measurementmentioning

confidence: 99%

Section: Allergic Rhinitismentioning

confidence: 99%

Nitric oxide in upper airways inflammatory diseases

2007

View full text Add to dashboard Cite

show abstract

“…For instance, Palm et al [64] found no change in nasal NO levels of patients with allergic rhinitis, whereas exhaled oral NO was increased. Also, other groups have not been successful in showing an evident increase in nasal NO in seasonal rhinitis, during as well as out of the pollen season [59,65].…”

Section: No In Allergic Rhinitismentioning

confidence: 99%

Nitric Oxide: A Promising Methodological Approach in Airway Diseases

Şahin

Klimek

Mullol

et al. 2011

Int Arch Allergy Immunol

View full text Add to dashboard Cite

Nitric oxide (NO) is a potent biological mediator, and has a regulatory role in a wide variety of cellular and tissue functions. In the upper and lower airways, NO has been suggested to be involved in different functions with regulatory, protective, defensive or damaging effects. It is obvious that NO plays an important role in host defense, and is liberated in the nose and the paranasal sinuses. This review aims to highlight some aspects of the origin and function of NO in airway diseases, such as allergic rhinitis, chronic rhinosinusitis with and without nasal polyps, primary ciliary dyskinesia, and cystic fibrosis. In conclusion, NO measurement may be a promising noninvasive diagnostic marker for airway pathologies.

show abstract

“…Data from adults and children shows alterations in nNO levels during allergic diseases [26][27][28][29][30]. Higher levels of eNO and nNO have been found in adult patients with OSA [31].…”

Section: Introductionmentioning

confidence: 96%