Characterization, antioxidant and cytotoxicity evaluation of green synthesized silver nanoparticles using Cleistanthus collinus extract as surface modifier

Kanipandian, Nagarajan; Kannan, Soundarapandian; Ramesh, Rengan; Subramanian, P.; Ramasamy, Thirumurugan

doi:10.1016/j.materresbull.2013.09.016

Cited by 137 publications

(55 citation statements)

References 33 publications

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“…1b, c), indicating the formation of AgNPs. It is an efficient and rapid method, which was very well explained by other researchers who worked with different plant systems (Muthukrishnan et al 2015;Kanipandian et al 2014;Kalaiselvi et al 2015). Change in color was due to the excitation of surface plasmon vibrations in metal nanoparticles (Ahmad et al 2003).…”

Section: Results and Discussion Characterizationmentioning

confidence: 86%

“…1a), which was specific for AgNPs. The UV-Vis absorption band in the current visible light region (420-450 nm) is an evidence of the presence of surface plasmon resonance (SPR) of AgNPs (Ramalingam et al 2014;Muthukrishnan et al 2015;Kanipandian et al 2014). A single SPR band resembles to the spherical nanoparticles, whereas two or more SPR bands correspond to the anisotropic molecules (Krishnaraj et al 2010).…”

Section: Uv-visible Spectramentioning

confidence: 99%

“…Though the synthesis of silver nanoparticles has been carried out by various methods such those based on reduction in solution, chemical and photochemical reactions (Henglein 1998), decomposition of silver compounds by thermal method (Viet Quang and Hoai Chau 2013) and microwave-assisted process (Jiang et al 2006), they involve the use of noxious chemicals. The green synthesis methods using plant extracts have been shown to be more advantageous owing to their simple methodology and eco-friendly nature (Muthukrishnan et al 2015;Ramalingam et al 2014;Kanipandian et al 2014;Singh et al 2013). Green synthesis of silver nanoparticles using various medicinal plants including, Acacia leucophloea (Murugan et al 2014), Aegle marmelos (Nithya Deva Krupa and Raghavan 2014), Alstonia scholaris (Shetty et al 2014), Solanum trilobatum, Syzygium cumini, Centella asiatica and Citrus sinensis (Logeswari et al 2013 synthesized silver nanoparticles from Dillenia indica (Singh et al 2013), Morinda pubescens (Inbathamizh et al 2013), and Ceropegia thwaitesii (Muthukrishnan et al 2015) have also been shown to exhibit in vitro antioxidant and antibacterial activities.…”

Section: Introductionmentioning

confidence: 99%

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Biogenic synthesis of silver nanoparticles and their antioxidant and antibacterial activity

Bhakya¹,

Muthukrishnan

Sukumaran³

et al. 2015

Appl Nanosci

367

178

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Nanomedicine utilizes biocompatible nanomaterials for diagnostic and therapeutic purposes. The present study reports the use of Helicteres isora root extract for the synthesis of silver nanoparticles (AgNPs). The synthesized AgNPs were initially noticed through visual color change from yellow to reddish brown and further confirmed by surface plasmonic resonance (SPR) band at 450 nm using UV-visible spectroscopy. Morphology and size of AgNPs were determined by transmission electron microscopy (TEM) analysis. X-ray diffraction (XRD) study revealed crystalline nature of AgNPs. The prolonged stability of AgNPs was due to capping of oxidized polyphenols and carboxyl protein which was established by Fourier transform infrared spectroscopy (FTIR) study. In addition, the synthesized AgNPs were tested for antioxidant and antibacterial activities. It showed good antioxidant activity as compared to butylated hydroxytoluene (BHT) and ascorbic acid as standard antioxidant. It could be concluded that H. isora root extract can be used efficiently in the production of potential antioxidant and antibacterial AgNPs for commercial application.

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Section: Results and Discussion Characterizationmentioning

confidence: 86%

Section: Uv-visible Spectramentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Biogenic synthesis of silver nanoparticles and their antioxidant and antibacterial activity

Bhakya¹,

Muthukrishnan

Sukumaran³

et al. 2015

Appl Nanosci

367

178

View full text Add to dashboard Cite

show abstract

“…Our results also indicated that GBAgNPs synthesized from GBE were less toxic than previously reported biogenic AgNPs and AuNPs. 42,43 Hence, the current investigation suggests that at limited dosage, the GBE-mediated AgNPs can be used as effective skin drug delivery agents with minimum toxicity.…”

Section: In Vitro Cytotoxicity Assay Of Gbaunps and Gbagnpsmentioning

confidence: 95%

Ginseng-berry-mediated gold and silver nanoparticle synthesis and evaluation of their in vitro antioxidant, antimicrobial, and cytotoxicity effects on human dermal fibroblast and murine melanoma skin cell lines

Pérez¹,

Mathiyalagan²,

Markus³

et al. 2017

IJN

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There has been a growing interest in the design of environmentally affable and biocompatible nanoparticles among scientists to find novel and safe biomaterials. Panax ginseng Meyer berries have unique phytochemical profile and exhibit beneficial pharmacological activities such as antihyperglycemic, antiobesity, antiaging, and antioxidant properties. A comprehensive study of the biologically active compounds in ginseng berry extract (GBE) and the ability of ginseng berry (GB) as novel material for the biosynthesis of gold nanoparticles (GBAuNPs) and silver nanoparticles (GBAgNPs) was conducted. In addition, the effects of GBAuNPs and GBAgNPs on skin cell lines for further potential biological applications are highlighted. GBAuNPs and GBAgNPs were synthesized using aqueous GBE as a reducing and capping agent. The synthesized nanoparticles were characterized for their size, morphology, and crystallinity. The nanoparticles were evaluated for antioxidant, anti-tyrosinase, antibacterial, and cytotoxicity activities and for morphological changes in human dermal fibroblast and murine melanoma skin cell lines. The phytochemicals contained in GBE effectively reduced and capped gold and silver ions to form GBAuNPs and GBAgNPs. The optimal synthesis conditions (ie, temperature and v/v % of GBE) and kinetics were investigated. Polysaccharides and phenolic compounds present in GBE were suggested to be responsible for stabilization and functionalization of nanoparticles. GBAuNPs and GBAgNPs showed increased scavenging activity against 2,2-diphenyl-1-picrylhydrazyl free radicals compared to GBE. GBAuNPs and GBAgNPs effectively inhibited mushroom tyrosinase, while GBAgNPs showed antibacterial activity against Escherichia coli and Staphylococcus aureus . In addition, GBAuNPs were nontoxic to human dermal fibroblast and murine melanoma cell lines, and GBAgNPs showed cytotoxic effect on murine melanoma cell lines. The current results evidently suggest that GBAgNPs can act as potential agents for antioxidant, anti-tyrosinase, and antibacterial activities. In addition, GBAuNPs can be further developed into mediators in drug delivery and as antioxidant, anti-tyrosinase, and protective skin agents in cosmetic products. Consequently, the study showed the advantages of using nanotechnology and green chemistry to enhance the natural properties of GBs.

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“…DPPH assay are widely used to evaluate the radical-scavenging ability of green synthesized nanoparticles. In the present study, DPPH, a stable free radical with a characteristic absorption at 517nm was used to study the radical-scavenging effects 19 . The DPPH scavenging assay exhibited effective inhibition activity of AgNPs when compared with the standard BHT (butylated hydroxytoluene).…”

Section: Antioxidant Activity Of Agnpsmentioning

confidence: 99%

Novel Biogenic Synthesis of Agnps From Seed Extract of Eugenia Uniflora L.: In Vitro Assessment of Their Antioxidant, Antimicrobial and Cytotoxic Potential

Dugganaboyana¹,

Sharanya²,

Kumar³

et al. 2017

Int. Res. J. Pharm.

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Here, we explored the medicinal uses of the novel biogenic silver nanoparticles of Eugenia uniflora L. (E. uniflora) seed extract as a cost effective, eco-friendly, reducing and stabilizing compounds. This study describes the synthesis of silver nanoparticles from Eugenia uniflora L. (E. uniflora) seed extract and their antioxidant, antibacterial and cytotoxic potential. Biosynthesis of AgNPs was monitored by UV-visible spectroscopy which revealed intense surface plasmon resonance bands at 447 nm and X-ray diffraction were employed to identify various functional groups and crystalline nature of AgNPs. Scanning electron microscopy studies demonstrated that synthesized particles were crystalline in nature with average size of 78-100nm. In vitro antioxidant effects were analyzed by butylated hydroxytoluene (BHT)) and 2,2-diphenyl-1-picrylhydrazyl (DPPH), which exhibited antioxidant activity there in the particles could scavenges the stable free radical DPPH of 75% to that o positive control BHT. The value of 50% inhibition concentration (IC50) of Standard BHT is 65.55 and E. uniflora is 38.63µg/ml. The antibacterial activity of green AgNPs displayed better zone of inhibition against selected human pathogens. The present study also investigated the toxicity effect of biogenic AgNPs against human prostate cancer cells (PC-3) and the inhibitory concentrations (IC50) were found to be 6.25μg/ml, respectively. It could be concluded that E. uniflora seed extract AgNPs can be used efficiently for potential antioxidant, antibacterial and cytotoxic potential AgNPs with potent biomedical applications.

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Characterization, antioxidant and cytotoxicity evaluation of green synthesized silver nanoparticles using Cleistanthus collinus extract as surface modifier

Cited by 137 publications

References 33 publications

Biogenic synthesis of silver nanoparticles and their antioxidant and antibacterial activity

Biogenic synthesis of silver nanoparticles and their antioxidant and antibacterial activity

Ginseng-berry-mediated gold and silver nanoparticle synthesis and evaluation of their in vitro antioxidant, antimicrobial, and cytotoxicity effects on human dermal fibroblast and murine melanoma skin cell lines

Novel Biogenic Synthesis of Agnps From Seed Extract of Eugenia Uniflora L.: In Vitro Assessment of Their Antioxidant, Antimicrobial and Cytotoxic Potential

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