Characterization, anti-oxidation and anti-inflammation of polysaccharides by Hypsizygus marmoreus against LPS-induced toxicity on lung

Liu, Min; Li, Shangshang; Wang, Xiuxiu; Zhu, Yongfa; Zhang, Jianjun; Liu, Hui

doi:10.1016/j.ijbiomac.2018.01.010

Cited by 49 publications

(23 citation statements)

References 37 publications

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“…Significant attention has been paid to the extraction and bioactivity of biomacromolecules, such as polysaccharides. Polysaccharides obtained from natural sources tend to exhibit a low toxicity in addition to various bioactivities, such as anti-bacterial, anti-inflammatory activities [91,92]. In recent years, studies reporting their inhibition of UA production and enhancement of UA elimination have been published, indicating that polysaccharides may be a candidate for the development of new natural anti-HUA agents.…”

Section: Polysaccharidesmentioning

confidence: 99%

Bioactive Compounds from Plant-Based Functional Foods: A Promising Choice for the Prevention and Management of Hyperuricemia

Jiang

Gong

et al. 2020

Foods

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Hyperuricemia is a common metabolic disease that is caused by high serum uric acid levels. It is considered to be closely associated with the development of many chronic diseases, such as obesity, hypertension, hyperlipemia, diabetes, and cardiovascular disorders. While pharmaceutical drugs have been shown to exhibit serious side effects, and bioactive compounds from plant-based functional foods have been demonstrated to be active in the treatment of hyperuricemia with only minimal side effects. Indeed, previous reports have revealed the significant impact of bioactive compounds from plant-based functional foods on hyperuricemia. This review focuses on plant-based functional foods that exhibit a hypouricemic function and discusses the different bioactive compounds and their pharmacological effects. More specifically, the bioactive compounds of plant-based functional foods are divided into six categories, namely flavonoids, phenolic acids, alkaloids, saponins, polysaccharides, and others. In addition, the mechanism by which these bioactive compounds exhibit a hypouricemic effect is summarized into three classes, namely the inhibition of uric acid production, improved renal uric acid elimination, and improved intestinal uric acid secretion. Overall, this current and comprehensive review examines the use of bioactive compounds from plant-based functional foods as natural remedies for the management of hyperuricemia.

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Section: Polysaccharidesmentioning

confidence: 99%

Bioactive Compounds from Plant-Based Functional Foods: A Promising Choice for the Prevention and Management of Hyperuricemia

Jiang

Gong

et al. 2020

Foods

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“…LPS can stimulate overproduction of inammatory cytokines, leading to excessive inammatory responses. 37 The imbalance between pro-inammatory cytokines and anti-inammatory cytokines is a hallmark of the pathogenesis of inammation. 38 The anti-inammatory effect of WPSPP-1 on LPS-induced inammatory mice is shown in Fig.…”

Section: 4mentioning

confidence: 99%

Anti-inflammatory activity of a water-soluble polysaccharide from the roots of purple sweet potato

et al. 2020

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“…Presently the effects of mushroom polysaccharides have been studied intensively which consist of antioxidant [4], anti-inflammation [5], anti-hyperglycemia [6], anti-tumor [7] and immunostimulation [8]. Nevertheless the process of discovery of new polysaccharides is still on-going.…”

Section: Fractionation 40mentioning

confidence: 99%

Extraction and Fractionation of Polysaccharides from a Selected Mushroom Species, Ganoderma lucidum: A Critical Review

Choong¹,

Ellan²,

Chen³

et al. 2019

Fractionation

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Fractionation plays a big role in most of the sample processing especially in mushroom polysaccharides extraction. This intermediate step will determine further purification process which will lead to the type of polysaccharides that will be obtained. Four types of Ganoderma lucidum cultured medium used in the research papers were randomly chosen. They are spores, mycelia, fruiting body and fermentation broth. For water soluble polysaccharides, hot water extraction is typically applied. The following ethanol precipitation could be appropriate used to sediment the component with OH-group including polysaccharide. The next step of fractionation consist of anion exchange chromatography or gel filtration enhance the purity of polysaccharides. Using these extraction and fractionation techniques, high quality polysaccharides could be successfully obtained from the mushroom that are useful for further studies. This review examined the various extraction and fractionation techniques used in the study of polysaccharides from G. lucidum.

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Characterization, anti-oxidation and anti-inflammation of polysaccharides by Hypsizygus marmoreus against LPS-induced toxicity on lung

Cited by 49 publications

References 37 publications

Bioactive Compounds from Plant-Based Functional Foods: A Promising Choice for the Prevention and Management of Hyperuricemia

Bioactive Compounds from Plant-Based Functional Foods: A Promising Choice for the Prevention and Management of Hyperuricemia

Anti-inflammatory activity of a water-soluble polysaccharide from the roots of purple sweet potato

Extraction and Fractionation of Polysaccharides from a Selected Mushroom Species, Ganoderma lucidum: A Critical Review

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