Characterization and comparison of lipids in bovine colostrum and mature milk based on UHPLC-QTOF-MS lipidomics

Liang, Xiaona; Li, Qilong; Kang, Shimo; Cao, Xiaohong; Zheng, Yan; Wu, Junrui; Wu, Rina; Li, Mohan; Yang, Mei; Yue, Xiqing

doi:10.1016/j.foodres.2020.109490

Cited by 55 publications

(24 citation statements)

References 38 publications

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“…Using UHPLC-Q-TOF MS, 335 lipids across 13 categories were identified in donkey milk (Li et al, 2020b) and cow milk (Li et al, 2020a) (Liu et al, 2020). In another study, 13 lipid classes were identified in human, bovine, and caprine milk using UHPLC-Q-TOF MS, including TG, DG, SM, PC, Cer, HexCer, Hex2Cer, PE, PG, PS, PI, PA, and CL (Wang et al, 2020).…”

Section: Lipidomics For Milk Quality Evaluationmentioning

confidence: 99%

“…Using UHPLC-Q-TOF MS, 335 lipids across 13 categories were identified in donkey milk ( Li et al, 2020b ) and cow milk ( Li et al, 2020a ) at different lactation stages, including CL, PA, PC, PE, PG, PI, PS, Cer, SMs, species of simple Glc series (HexCer), Hex2Cers, DG, and TG. A total of 756 lipids across 14 categories were identified in the milk of goats from different geographical origins and at different lactation stages using UPLC-Q-Exactive Orbitrap MS, including 5 CL, 45 Cer, 17 LPCs, 4 LPEs, 36 PCs, 80 PEs, 9 PGs, 22 PIs, 2 acyl carnitine species, 55 HexCer, 56 SMs, 17 FA, 15 DG, and 416 TG ( Liu et al, 2020 ).…”

Section: Application Of Lipidomics To Assess Food From Farm Animalsmentioning

confidence: 99%

See 1 more Smart Citation

A Comprehensive Review of Lipidomics and Its Application to Assess Food Obtained from Farm Animals

Song¹,

Cai²,

Song³

et al. 2022

Food Sci Anim Resour

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Lipids are one of the major macronutrients essential for adequate growth and maintenance of human health. Their structure is not only complex but also diverse, which makes systematic and holistic analyses challenging; consequently, little is known regarding the relationship between phenotype and mechanism of action. In recent years, rapid advancements have been made in the fields of lipidomics and bioinformatics. In comparison with traditional approaches, mass spectrometry-based lipidomics can rapidly identify as well as quantify >1,000 lipid species at the same time, facilitating comprehensive, robust analyses of lipids in tissues, cells, and body fluids. Accordingly, lipidomics is now being widely applied in various fields, particularly food and nutrition science. In this review, we discuss lipid classification, extraction techniques, and detection and analysis using lipidomics. We also cover how lipidomics is being used to assess food obtained from livestock and poultry. The information included herein should serve as a reference to determine how to characterize lipids in animal food samples, enhancing our understanding of the application of lipidomics in the field in animal husbandry.

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Section: Lipidomics For Milk Quality Evaluationmentioning

confidence: 99%

Section: Application Of Lipidomics To Assess Food From Farm Animalsmentioning

confidence: 99%

A Comprehensive Review of Lipidomics and Its Application to Assess Food Obtained from Farm Animals

Song¹,

Cai²,

Song³

et al. 2022

Food Sci Anim Resour

View full text Add to dashboard Cite

show abstract

“…The natural presence of nutritious and physiologically active components such as immunoglobulins, growth factors, hormones, and lactoferrins drives the increased interest in BC. Generically, BC is a yellowish–reddish viscous fluid secreted from mammary glands immediately after parturition that is predominantly composed of nutritious and bioactive components in a low-volume high-density format [ 1 , 2 , 3 ]. The prime constituents of BC were categorized into (a) immune factors, namely immunoglobins (IgG, IgA, and IgM), lactoferrin (LF), lysozyme, lactoperoxidase, microRNA, glycoconjugates, B and T lymphocytes, leukocytes, interleukins, and other proline-rich polypeptides; (b) growth factors, namely insulin growth factors (IGF-I and -II), epithelial growth factors, growth hormones, platelet-derived growth factors, fibroblast growth factor, and epidermal growth factor; and (c) nutritional components, namely fatty acids, conjugated linoleic acid, oligosaccharides (major, neutral, and acidic), amino acids, vitamins, and minerals [ 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

et al. 2022

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Bovine colostrum (BC) is the initial mammary secretion after parturition, which is nature’s bountiful source consisting of nutritional and bioactive components present in a highly concentrated low-volume format. All mammalian newborns require colostrum to enhance physiological processes such as lifelong immunity, gastrointestinal development, and resistance to microbial infections. The genetic, environmental, and processing methods can all have an impact on the biochemical contents of BC and its supplements. BC and its derivatives have been intensively researched for their potential use in functional foods, medicines, and animal feed. Evidence from clinical studies suggests that BC products are well-tolerated, nontoxic, and safe for human ingestion. Functional foods, feed, and pharmaceutical formulations based on bovine colostrum are playing noteworthy roles in the development of innovative products for promoting health and the prevention of chronic illnesses. This systematic review sheds light on recent research on (a) the effects of processing techniques on BC components, (b) emerging techniques used in the isolation and identification of novel components, (c) BC-based functional foods for human consumption and animal feed supplements, and (d) the role of BC in current drug delivery, as well as future recommendations.

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“…Colostrum is a unique liquid, forming in mammary glands during only several days after delivery [6,7] and is rich in immunoglobulins and other growth factors [8] with the extremely wide spectrum of biologically active substances [9]. It is demonstrated, that immunoglobulins transmission to newborns by colostrums is called colostrums immunity [5], and it is the most important survival factor of newborns in the early postnatal period [10].…”

Section: Introductionmentioning

confidence: 99%

Low-molecular components of colostrum as a regulator of the organism redox-system and biological antidote

et al. 2021

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The protein composition in the diapason of molecular masses from 4800 to 9500 Dа has been studied in colostrum, taken from different cows, and manifested the expressed biological activity. For this aim, an influence of low-molecular components of colostrum on some physiological parameters (change of body mass and temperature) at intoxication of animals (Wistar rats) by blue stone has been studied. An influence of colostrum low-molecular components on parameters of the organism redox-system (content of hyperperoxides of lipids and activity of glutathione peroxidase) in the blood serum of animals has been studied. For determining integral characteristics of colostrum components, electric conductivity of skim colostrum and one of colostrum with low-molecular proteins (less than 10 000 Dа), taken from different cows, were used. The aim of this work is to study interconnections of an influence of colostrum low-molecular proteins on models of organism intoxication by cooper ions. It is demonstrated, that the colostrum composition includes 25–35 different proteins with a molecular mass from 4800 to 9500 Dа. The number and ratio between protein fractions depend on individual physiological-biochemical characteristics of producers. It has been revealed, that there is no direct dependence between the protein content in a measuring cell (2 mg/ml, 4 mg/ml and 10 mg/ml) with skim colostrum and electric conductivity change, and this dependence is different for skim colostrum, taken from different cows. Individual differences are manifested both at electric conductivity change and by the content of colostrum low-molecular proteins in a measuring cell. It is demonstrated, that colostrum low-molecular components can eliminate the toxic effect of blue stone on the organism, which mechanisms are connected with a balance shift in the system “prooxidants↔antioxidants” towards antioxidants. The electric conductivity of colostrum components may be used as an express-method for evaluating biologically active substances of colostrum

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Characterization and comparison of lipids in bovine colostrum and mature milk based on UHPLC-QTOF-MS lipidomics

Cited by 55 publications

References 38 publications

A Comprehensive Review of Lipidomics and Its Application to Assess Food Obtained from Farm Animals

A Comprehensive Review of Lipidomics and Its Application to Assess Food Obtained from Farm Animals

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

Low-molecular components of colostrum as a regulator of the organism redox-system and biological antidote

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