Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)

Ureña-Saborío, Hilary; Rodríguez, Gerardo; Madrigal‐Carballo, Sergio; Gunasekaran, Sundaram

doi:10.1016/j.mtla.2020.100687

Cited by 15 publications

(12 citation statements)

References 43 publications

(26 reference statements)

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“…In its turn, the use of biodegradable polymer scaffolds with the addition of calcium hydroxyapatite (HAP) is a promising and developing area of regenerative endodontic therapy [15][16][17][18]. HAP promotes hard bone tissue formation, which is extremely important for endodontic therapy of apical periodontitis with progressive bone resorption around the tooth root [19].…”

Section: Introductionmentioning

confidence: 99%

Nanofibrous biologically soluble scaffolds as an effective drug delivery system

Daulbayev¹,

Sultanov²,

Aldasheva³

et al. 2021

Comptes Rendus. Chimie

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In this article, the synthesis of biocompatible fibrous scaffolds with antimicrobial properties based on polycaprolactone/hydroxyapatite/amoxicillin and study of their surface morphology, antimicrobial effect, and drug release are discussed. Hydroxyapatite (1-2 µm, 97%) synthesized from biologically waste material (eggshell) was added to the composite scaffolds as a bone-replacement material. The scaffolds' antimicrobial properties were evaluated against S. aureus and E. faecalis. The scaffolds possessed a sustained drug release from the scaffolds amounted to about 94% of the antibiotic's total weight over a 4-week observation period. Agar diffusion confirmed the antimicrobial properties of the scaffolds against specific bacteria.

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Section: Introductionmentioning

confidence: 99%

Nanofibrous biologically soluble scaffolds as an effective drug delivery system

Daulbayev¹,

Sultanov²,

Aldasheva³

et al. 2021

Comptes Rendus. Chimie

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“…The chemical profiles of PAC:PCL ESNF were determined by attenuated total reflectance Fourier‐transform infrared spectroscopy (ATR‐FTIR; Nicolet 4700, Thermo Scientific, Gran Island, NY), while thermal properties were analyzed using a thermogravimetric analyzer (TGA; Q100, TA Instruments, Lindon, UT) at 20°C/min over a temperature scan range of 50–400°C in a 20 ml/min nitrogen atmosphere 16 . The swelling property of the nanofibers was determined by weighing the ESNF samples before and after immersing them in 1× D‐PBS + Ca 2+ /Mg 2+ at 37°C for 300 min.…”

Section: Methodsmentioning

confidence: 99%

“…During electrospinning, an electrified jet of a highly viscous polymeric solution is continuously stretched due to electrostatic charges under a high voltage applied to the system to produce a solidified polymeric fiber 13,14 . We have previously reported the ability to incorporate plant‐based active ingredients into Electrospun nanofibers (ESNF), which results in an improvement of the biological properties of a single biopolymer matrix 15,16 . Herein, using ExPEC strain 5011 (EXPEC‐5011) as a model organism, we report the fabrication of PAC:PCL composite ESNF and its ability to entrap pathogenic bacteria when ESNF is used as a biofilter or as a nanocoating agent.…”

Section: Introductionmentioning

confidence: 99%

Cranberry proanthocyanidins composite electrospun nanofibers as a potential alternative for bacterial entrapment applications

et al. 2022

Self Cite

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The interaction between A‐type interflavan bonds from cranberry proanthocyanidins (PAC) and surface virulence factors of extra‐intestinal pathogenic Escherichia coli (ExPEC) was studied. Electrospun nanofibers (ESNF) were fabricated using PAC and polycaprolactone (PCL) solutions and their physical and chemical properties were characterized. The ability of PAC:PCL composite ESNF to interact with and entrap ExPEC strain 5011 (ExPEC‐5011) was evaluated in vitro by plate culturing and when formulated as a biofilter and nanocoating. As a biofilter, the PAC:PCL ESNF exhibited a dose‐dependent ability to entrap ExPEC‐5011. Images from scanning electron and fluorescent microscopies revealed that ESNF sections with higher amounts of PAC led to higher bacterial entrapment. The effectiveness PAC:PCL ESNF to bind ExPEC when applied as a nanocoating was studied using ESNF‐coated polyvinyl chloride intermittent catheter. Results indicate that ExPEC‐5011 was entrapped well into the PAC:PCL ESNF coating on the catheter. Overall, our results suggest that incorporating the biomolecule PAC in ESNF is a potential means for applications requiring bacterial entrapment, such as biofunctionalization, biofiltration, and surface coating, among others.

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“…Substrate roughness and wettability possess a very important role in protein absorption and cellular attachment, therefore significantly contributing to the biological performance of implanted devices. The addition of AgNPs within electrospun scaffolds of CMC/PVA and PCL loaded with rambutan polyphenolic extract determined higher cellular proliferation rates due to surface modification [ 329 , 330 ]. Titanium oxide nanotube array coated with AgNPs-embedded polydopamine layer was assessed as a feasible option for arthroplasty [ 331 ].…”

Section: Silver Nanoparticles For Tissue Engineeringmentioning

confidence: 99%

An Updated Review on Silver Nanoparticles in Biomedicine

et al. 2020

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Silver nanoparticles (AgNPs) represent one of the most explored categories of nanomaterials for new and improved biomaterials and biotechnologies, with impressive use in the pharmaceutical and cosmetic industry, anti-infective therapy and wound care, food and the textile industry. Their extensive and versatile applicability relies on the genuine and easy-tunable properties of nanosilver, including remarkable physicochemical behavior, exceptional antimicrobial efficiency, anti-inflammatory action and antitumor activity. Besides commercially available and clinically safe AgNPs-based products, a substantial number of recent studies assessed the applicability of nanosilver as therapeutic agents in augmented and alternative strategies for cancer therapy, sensing and diagnosis platforms, restorative and regenerative biomaterials. Given the beneficial interactions of AgNPs with living structures and their nontoxic effects on healthy human cells, they represent an accurate candidate for various biomedical products. In the present review, the most important and recent applications of AgNPs in biomedical products and biomedicine are considered.

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Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)

Cited by 15 publications

References 43 publications

Nanofibrous biologically soluble scaffolds as an effective drug delivery system

Nanofibrous biologically soluble scaffolds as an effective drug delivery system

Cranberry proanthocyanidins composite electrospun nanofibers as a potential alternative for bacterial entrapment applications

An Updated Review on Silver Nanoparticles in Biomedicine

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