Characteristics, Properties and Analytical Methods of Amoxicillin: A Review with Green Approach

Marco, Bianca Aparecida de; Natori, Jéssica Sayuri Hisano; Fanelli, Stefany; Tótoli, Eliane Gandolpho; Salgado, Hérida Regina Nunes

doi:10.1080/10408347.2017.1281097

Cited by 52 publications

(30 citation statements)

References 51 publications

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“…Since the ability of peptides to hinder microbial growth alone was evaluated, we then investigated their synergistic ability with other traditional antimicrobials. Amoxicillin is a widely applied antibiotic that is capable of blocking the synthesis of glycopeptides, a significant component of staphylococcal cell walls, by specifically inactivating transpeptidase in bacteria ( de Marco et al, 2017 ). Terbinafine is a allylamine antifungal agent frequently used in the treatment of the superficial fungal infections.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti-inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines

Tang

Yang

et al. 2021

Front. Microbiol.

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The incidence of zoonotic Staphylococcus pseudintermedius and Microsporum canis infections is rapidly growing worldwide in the context of an increasing frequency of close contact between animals and humans, presenting challenges in both human and veterinary medicine. Moreover, the development of microbial resistance and emergence of recalcitrant biofilms, accompanied by the insufficiency of new antimicrobial agents, have become major obstacles in treating superficial skin infections caused by various microbes including S. pseudintermedius and M. canis. Over recent years, the prospects of antimicrobial peptides as emerging antimicrobials to combat microbial infections have been demonstrated. In our study, two novel short-chain peptides, namely, allomyrinasin and andricin B, produced by Allomyrina dichotoma and Andrias davidianus, were revealed to exhibit potent antimicrobial efficacy against clinical isolates of S. pseudintermedius and M. canis with remarkable and rapid fungicidal and bactericidal effects, while allomyrinasin exhibited inhibition of biofilm formation and eradication of mature biofilm. These peptides displayed synergistic activity when combined with amoxicillin and terbinafine against S. pseudintermedius and M. canis. Cytoplasmic leakage via cytomembrane permeabilization serves as a mechanism of action. Extremely low hemolytic activity and serum stability in vitro, as well as superior anti-infective efficacy in reducing bacterial counts and relieving the inflammatory response in vivo, were detected. The potent antibacterial, antifungal, and anti-inflammatory activities of allomyrinasin and andricin B might indicate promising anti-infective alternatives for the treatment of S. pseudintermedius and M. canis infections in the context of human and veterinary medicine.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti-inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines

Tang

Yang

et al. 2021

Front. Microbiol.

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“…The use of methods, considered green, makes unnecessary the remediation of environmental impacts often observed today [6,[60][61][62][63]70,7,[64][65][66] . Some methods for evaluation of rifaximin contemplate this thought because they use only ethanol and water, instead of methanol in the UV method, for example, or simply just potassium bromide, as shown in Table 1.…”

Section: Methodsmentioning

confidence: 99%

Status of Rifaximin: A Review of Characteristics, Uses and Analytical Methods

Kogawa

Salgado

2018

Critical Reviews in Analytical Chemistry

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Rifaximin, an oral antimicrobial, has many advantages because it is selective intestine, has minimal adverse effects and is used for the treatment of some diseases such as hepatic encephalopathy, irritable bowel syndrome, travelers' diarrhea, ulcerative colitis, Clostridium difficile and acute diarrhea. Rifaximin in the form of 200 mg tablets is commercially available. The crystalline α form is therapeutically safe and effective. In most of the official compendia, rifaximin has no monograph and in none of them is there a monograph for rifaximin tablets. The literature, however, contemplates this gap with varied methods. The literature presents some methods for evaluation of rifaximin in both biological fluid and pharmaceutical product. High performance liquid chromatography stands out for the evaluation of rifaximin. Most of the methods reported in the literature are for pharmaceuticals products. They use (1) toxic organic solvents, harmful to the operator and the environment, and/or (2) buffer solution, which has a shorter service life and requires time-consuming washes of the chromatographic system generating more waste. So, this work aims to discuss (i) properties; (ii) applications; (iii) polymorphism and (iv) analytical methods of rifaximin by the look of green chemistry. This review shows an extremely current topic of great importance to the chemical-pharmaceutical area and everything it involves, since the analytical process until the impact on the environment in which it is embedded.

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“…In it there will be no chief but leaders. In it there will be no the vision only in the final product but in the whole chain, in order to be sustainable, green and clean (Marco and Salgado, 2017, Marco et al, 2017, Trindade et al, 2017). Thus, automatically, the company grows.…”

Section: Impacts Of Green Chemistrymentioning

confidence: 99%

Evolution of green chemistry and its multidimensional impacts: A review

Marco

Rechelo

Tótoli

et al. 2019

Saudi Pharmaceutical Journal

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283

129

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The growing process of industrialization was a milestone for world economic evolution. Since the 1940s, social movements have revolutionized green chemistry and provided shifts in industrial positions and sustainable processes with advances in environmental impact and awareness of companies and population. Paul Anastas and John Warner, in the 1990s, postulated the 12 principles of Green Chemistry, which are based on the minimization or non-use of toxic solvents in chemical processes and analyzes, as well as, the non-generation of residues from these processes. One of the most active areas of Research and Development in Green Chemistry is the development of analytical methodologies, giving rise to the so-called Green Analytical Chemistry. The impacts of green chemistry on pharmaceutical analyzes, environmental, population, analyst and company are described in this review and they are multidimensional. Every choice and analytical attitude has consequences both in the final product and in everything that surrounds it. The future of green chemistry as well as our future and the environment is also contemplated in this work.

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Characteristics, Properties and Analytical Methods of Amoxicillin: A Review with Green Approach

Cited by 52 publications

References 51 publications

Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti-inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines

Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti-inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines

Status of Rifaximin: A Review of Characteristics, Uses and Analytical Methods

Evolution of green chemistry and its multidimensional impacts: A review

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