Characteristics of the succinate transport into Saccharomices cerevisiae cellsafter prolonged cold preincubation

Aliverdieva, D. A.; Mamaev, D. V.; Lagutina, L S

doi:10.1134/s0003683809050111

Cited by 3 publications

(2 citation statements)

References 25 publications

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“…It was shown that the yeast cell can rearrange the metabolic pathways depending on the cultivation conditions (Aliverdieva et al, 2006(Aliverdieva et al, , 2009. The study of the influence of geothermal waters in the nutrient medium on the physiological and biochemical properties of Saccharomyces have resulted in a substantial extension of the understanding of yeast metabolism (Table 1).…”

Section: Resultsmentioning

confidence: 99%

Using geothermal waters of Dagestan in scientific and biotechnological processes

2016

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The current state and prospects of the development of ground waters in Dagestan have been reviewed. A complex theoretical and experimental study of the mechanisms by which biologically active sub stances of geothermal waters influence yeast metabolism has served as the basis for the development of bio technologies to produce biochemically active Saccharomyces strains, bakery products, and ethanol. The application of new technology products in various industries opens up possibilities for creating high perfor mance agroindustrial enterprises in both Dagestan and other regions of Russia with geothermal resources.

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Section: Resultsmentioning

confidence: 99%

Using geothermal waters of Dagestan in scientific and biotechnological processes

2016

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“…Modification of Bradford method was used for determination of mitochondrial protein [9]. Rates of succinate oxidation of rat liver mitochondria (v) and the mitochondria respiratory control (RC) ratio were determined in thermostatic cell at 25ºC with quick response oxymetric electrode [10]. In the presence of succinate in all used incubation media the Chance RC was about 5.0 -5.2.…”

Section: Methodsmentioning

confidence: 99%

Mastoparan Dissipates Mitochondrial Transmembrane Potential in the Physiological (ADP-LIKE) Range

Dinara¹

2019

Int. J. Membrane Sci. Techno.

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Experimental studies of antimicrobial peptides as potential drugs having a pore-forming mechanism of action have attracted increasing interest for clinical applications due to their broad spectrum of activity. Here in a short report, we describe an experimental approach for testing potential drugs using rat liver mitochondria as model and pore-forming peptide mastoparan. We have used tightly coupled mitochondria and a sensitive oximetric cell to study activation of mitochondrial respiration by mastoparan and showed limited dissipation of their transmembrane potential in the presence of this peptide. Mastoparan stabilized this potential synchronously with stabilization of mitochondrial State 4 respiration rate (v4). It was concluded that mastoparan dissipates mitochondrial transmembrane potential only in the physiological (adenosine diphosphate (ADP)-like) range. The comparison of side effects of pore-forming peptides on mitochondrial transmembrane potential may be useful for toxicity testing of new drugs.

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Evaluation of molecularity of rate-limiting step of pore formation by antimicrobial peptides studied using mitochondria as a biosensor

Aliverdieva

Mamaev

Snezhkova

et al. 2012

Toxicology in Vitro

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Characteristics of the succinate transport into Saccharomices cerevisiae cellsafter prolonged cold preincubation

Cited by 3 publications

References 25 publications

Using geothermal waters of Dagestan in scientific and biotechnological processes

Using geothermal waters of Dagestan in scientific and biotechnological processes

Mastoparan Dissipates Mitochondrial Transmembrane Potential in the Physiological (ADP-LIKE) Range

Evaluation of molecularity of rate-limiting step of pore formation by antimicrobial peptides studied using mitochondria as a biosensor

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