Characteristics of the Epidemic Situation Associated with Acute Respiratory Viral Infections in the Russian Federation during the Pandemic Spread of COVID-19

Semenenko, Т. A.; Акимкин, В. Г.; Burtseva, Elena; Nozdracheva, Anna; Симонова, Е. Г.; Tutelyan, A.V.; Углева, С. В.; Кузин, С. Н.

doi:10.31631/2073-3046-2022-21-4-4-15

Cited by 15 publications

(2 citation statements)

References 19 publications

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“…Изучение распространенности специфических антител к возбудителям инфекционных болезней среди различных групп населения с использованием образцов из биобанка расширило представления об особенностях эпидемиологических процессов таких социальнозначимых инфекций, как грипп и острые респираторные вирусные инфекции, вирусные гепатиты, инфекции, управляемые средствами вакцинопрофилактики (корь, краснуха и др. ), позволило судить об истинном уровне заболеваемости, эффективности вакцинопрофилактики отдельных инфекций и принятии взвешенных решений при внесении корректировок в календарь прививок [15][16][17][18][19].…”

Section: ключевые моменты что известно о предмете исследования?unclassified

Possibilities of a biobank for serological monitoring of infectious morbidity

Svitich,

Zverev,

Solomay

et al. 2023

Cardiovasc Ther Prev

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Currently, monitoring infectious morbidity, control and forecasting the epidemic process is a topical health problem.Aim. To analyze the capabilities of the biobank for serological monitoring of infectious diseases using the Epstein- Barr virus (EBV), which is associated with infectious mononucleosis, as well as somatic pathology, including cancer.Material and methods. Using the quantitative enzyme- linked immunosorbent assay for specific antibodies to various EBV proteins, we studied blood serum samples from healthy individuals (2010, 2016, 2019, 2020, 2021 and 2022) from the collection of the N. F. Gamaleya National Center of Epidemiology and Microbiology.Results. For the first time, the intensity of EBV epidemic process among apparently healthy adult residents of the capital was assessed using samples of biological material and a biobank information database. At the time of examination, 0,8% of individuals were not infected with EBV, and 9,4% suffered reactivation of a chronic infection. There were no significant changes in detection rate of markers over the years.Conclusion. Certified collections of blood sera can be effectively used to study population immunity, the prevalence of individual infections, population protection nationwide, etc.

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Section: ключевые моменты что известно о предмете исследования?unclassified

Possibilities of a biobank for serological monitoring of infectious morbidity

Svitich,

Zverev,

Solomay

et al. 2023

Cardiovasc Ther Prev

Self Cite

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“…The course of mixed infection against the background of an aggravated premorbid state increases the risk of developing severe forms and adverse outcomes of the disease [1,2] Within the territory of the Russian Federation (RF), an annual increase in cases of various infectious diseases is recorded in patients aged 0 to 17 years. The leading positions in terms of the incidence in childhood belong to acute respiratory viral infections (ARVI), which are represented by a group of numer-ous independent diseases characterized by damage to the upper and lower respiratory tract of a child by viruses belonging to various genera and families [9].…”

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Analysis of the infectious morbidity in the children's population in the city of Krasnodar

Oguntimehin,

Jalalova,

Krasnikova

et al. 2023

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Aim. Our aim hereof is to assess the status of infectious morbidity in the pediatric population in the territory of the Russian Federation and the City of Krasnodar in the period 2021-2022 by an example of the State Health Institution “Pediatrics Polyclinic No 2”, Department of Health Care of the City of Krasnodar. Material and Methods. Our work has been completed with use of official statistical data of the Federal Service of the state statistics of the Russian Federation, the database of Rospotrebnadzor of the Krasnodar territory, statistical data set collections of FGBI “The Central Research Institute of the Management and Information of Public Health Care” at the Ministry of Health Care of the Russian Federation. A retrospective analysis was performed using data from the State Report “The state of sanitary and epidemiological welfare of the population in the Russian Federation in 2021”. Statistical processing was carried out using GraphPad Prism 5.0 and Word Excel. Results. According to the data on the sanitary and epidemiological well-being of the population, an increase in the number of cases of infectious and parasitic diseases was recorded in the Russian Federation in 2021. The sharp rise in the incidence of infectious diseases is directly related to the spread of the new COVID-19 infection. The incidence of ARVI among children in 2021 was 68,062.49 per 100,000 that is 15.4% higher than in 2020. In Krasnodar, there were 236,332 patients diagnosed with infectious diseases in 2021. According to the data submitted by Branch No. 2 of the Krasnodar City Pediatrics Hospital at the City Health Care Department, the overall morbidity of children in the first year of life in 2022 has decreased. No cases of diphtheria, pertussis, poliomyelitis, measles, and viral hepatitis B were recorded by the outpatient clinical institution during the study period. As a part of preventive measures, children are routinely vaccinated by the Pediatrics Hospital No. 2; at the end of 2022, 98.3% of children in risk groups had been successfully treated and were allowed to be vaccinated. Conclusion. Over the period 2021-2022, there has been a decline in the incidence of diseases in children in the first year of life in the Krasnodar Region. At the same time, the recorded overall occurrence rate of acute upper respiratory tract infections of multiple and unspecified localization remains high that is due to the difficulty of diagnosing them at the early stages of infection, and, as a result, the effectiveness of their treatment is low that may be accompanied by high mortality.

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The Theory of Self-Regulation of Parasitary Systems and COVID-19

Akimkin,

Semenenko,

Dubodelov

et al. 2024

Annals RAMS

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Background. The COVID-19 pandemic once again confirmed the correctness of the theory of Academician V.D. Belyakov, according to which the basis for the development of the epidemic process is a phase change in the heterogeneity of the biological properties of the interacting populations of the pathogen and humans. In accordance with the theory of self-regulation of parasitic systems, changes are associated not only with genetic variability, but also with other polydeterminant characteristics of the pathogen: when new genovariants appeared, SARS-CoV-2 became less pathogenic for humans, but more contagious. This circumstance is important not only for theoretical, but also for practical epidemiology, as it makes it possible to predict the direction of development of the epidemic situation. Aims — to evaluate the manifestations of the epidemic process of the new coronavirus infection COVID-19 through the prism of the theory of self-regulation of parasitic systems. Methods. An epidemiological retrospective analysis of the incidence of COVID-19 was carried out, including the study of absolute and intensive incidence rates per 100,000 population, the dynamics of changes in the properties of the coronavirus population, and the identification of SARS-CoV-2 genovariants for the period from 03.2020 to 04.2023. To analyze SARS-CoV-2 genovariants at various stages of the pandemic, we used sequencing data presented on the SARS-CoV-2 genome information aggregation platform Virus Genome Aggregator of Russia (VGARus) — more than 248 thousand genetic sequences. Results. During the pandemic, there have been seven ups and downs in the incidence of COVID-19. During the period of circulation in the human population and adaptation to a new host, a significant amount of data has accumulated on the evolutionary changes in the SARS-CoV-2 genome, taking into account the trends in the acquisition of new epidemiological properties. Conclusion. An analysis of the manifestations of the epidemic process of COVID-19, as a classic aerosol anthroponosis, confirmed the correctness of the theory of Academician V.D. Belyakov, according to which the basis of its development is a phase change in the heterogeneity of the biological properties of the interacting populations of the pathogen and humans, based on negative feedback in the process of self-regulation.

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Characteristics of the Epidemic Situation Associated with Acute Respiratory Viral Infections in the Russian Federation during the Pandemic Spread of COVID-19

Cited by 15 publications

References 19 publications

Possibilities of a biobank for serological monitoring of infectious morbidity

Possibilities of a biobank for serological monitoring of infectious morbidity

Analysis of the infectious morbidity in the children's population in the city of Krasnodar

The Theory of Self-Regulation of Parasitary Systems and COVID-19

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