Characteristics of Olfactory Disorders in Relation to Major Causes of Olfactory Loss

Temmel, Andreas F P; Quint, Christian; Schickinger-Fischer, Bettina; Klimek, Ludger; Stoller, Elisabeth; Hummel, Thomas

doi:10.1001/archotol.128.6.635

Cited by 458 publications

(438 citation statements)

References 20 publications

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“…Test-retest reliability and validity of the test was confirmed in several studies. [34][35][36] Recently, normative data from 3282 subjects have been published. 37 Each subject wore a sleeping mask to prevent visual identification of odor-dispensing pens.…”

Section: Assessment Of Olfactory Detection Threshold and Olfactory Idmentioning

confidence: 99%

Depressive symptoms and olfactory function in older adults

Ścińska

Wróbel

Korkosz

et al. 2008

Psychiatry Clin Neurosci

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Aims: Neuroimaging studies suggest a significant overlap between brain regions involved in the regulation of olfaction and mood. The aim of the present study was to search for correlations between depressive symptomatology measured by the 15-item Geriatric Depression Scale (GDS) and olfactory function assessed with Sniffin' Sticks in non-demented older adults (aged 53-79 years).Methods: Taste detection thresholds were also measured by means of electrogustometry on the anterior tongue. Results:No correlation was found between the GDS scores (range: 0-12) and olfactory thresholds or olfactory identification scores. Similarly, there was no relationship between depressive symptoms and electrogustometric thresholds. Subjects (n = 25) scoring Ն5 on the GDS were classified as 'depressed' and all other individuals (n = 60) were classified as 'nondepressed'. The two groups did not differ in terms of the olfactory measures and electrogustometric threshold. Conclusion:Depressive symptoms are not associated with any major olfactory deficit in non-clinical older adults.

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Section: Assessment Of Olfactory Detection Threshold and Olfactory Idmentioning

confidence: 99%

Depressive symptoms and olfactory function in older adults

Ścińska

Wróbel

Korkosz

et al. 2008

Psychiatry Clin Neurosci

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“…32 The most common known etiologies for anosmia are nasal/sinus congestion, upper respiratory tract infection, current smoking, head trauma, stroke, and epilepsy. 23,[33][34][35] Some investigators theorize that olfactory declines may be a consequence of autoimmune mechanisms 36 or neurodegenerative diseases. 37 The prognosis of olfactory dysfunction is influenced by certain demographic and clinical factors.…”

Section: Discussionmentioning

confidence: 99%

A possible correlation between vitamin D deficiency and loss of smell: 2 case reports

Kruse¹,

Cambron

2011

Journal of Chiropractic Medicine

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Objective: The purpose of this report is to present 2 cases of diminished olfaction that improved with increasing serum levels of vitamin D3. Clinical Features: Both patients were under the care of medical and chiropractic physicians for various complaints. A 47-year-old hyposmic woman was diagnosed with vitamin D deficiency who incidentally noticed a progressive return of her sense of smell while taking vitamin D supplements as prescribed by her medical doctor. A 34-year-old anosmic woman noticed a direct relationship with her ability to smell and vitamin D3 supplementation. Intervention and Outcome: Treatment for the first patient consisted of vitamin D supplementation of 10 000 IU a day. Her serum D3 levels increased substantially over a period of 8 months, at which time she reported a marked improvement in her sense of smell. The second patient was prescribed 50 000 IU of vitamin D a week; and she reported an increased ability to smell, although only the strongest of odors. Conclusion: A link between hypovitaminosis D and a diminished sense of smell was noted in these 2 individuals.

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“…: in some studies a relation was observed between the degree of olfactory loss and the risk of hazardous events [1,2]. Furthermore, nutritional status and many other topics related to the quality of life may be affected by the impairment of olfactory function [3], and loss of smell is accompanied by an increased risk of depression [4]. In addition, it is present in up to the 90% of Parkinson's Disease patients, and is considered one of the most prevalent troublesome nonmotor problems in this disease [5].…”

Section: Introductionmentioning

confidence: 99%

Anosmia after exposure to a pyrethrin-based insecticide: A case report

Gobba

Abbacchini

2012

International Journal of Occupational Medicine and Environmental Health

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We present the case of a subject developing anosmia, preceded by nasal transient irritation and short lasting phantosmia and torqosmia, upon re-entrance into a room treated with a pyrethrin-based insecticide. The concentration of the insecticide in the room is unknown, but relatively high levels are predicted basing upon the modality of exposure and by the irritation symptoms in the subject. Despite corticosteroids therapy, anosmia has persisted unmodified for more than three years; according to, and based on evidence in the literature on olfactory disturbance prognosis, anosmia in this patient is likely to be permanent. The significance of this case report is related to the current wide use of insecticides containing pyrethrin and pyrethroids and highlights the need for more adequate attention to lowering airborne concentrations of pyrethrins and pyrethroids prior to re-entering the treated rooms. In particular, in a closed space sprayed with pyrethrins and pyrethroids insecticide, any irritant symptoms and/or dysosmia should be immediately considered relevant warning signs, and must be avoided.

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Characteristics of Olfactory Disorders in Relation to Major Causes of Olfactory Loss

Abstract: Among many complaints of olfactory loss, the predominant ones were food related. This loss in QoL seemed to be of greater importance in younger than in older people, and women seem to be affected more strongly than men.

Cited by 458 publications

References 20 publications

Depressive symptoms and olfactory function in older adults

Depressive symptoms and olfactory function in older adults

A possible correlation between vitamin D deficiency and loss of smell: 2 case reports

Anosmia after exposure to a pyrethrin-based insecticide: A case report

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