Characteristics of Non-typhoidal Salmonella Isolates from Human and Broiler-chickens in Southwestern Seoul, Korea

Abstract

Non-typhoidal Salmonella (NTS) is an important commensal microorganism. The purpose of this study was to determine the epidemiological relation between NTS isolates from livestock and NTS isolates from human by analyzing antimicrobial susceptibilities and performing molecular typing. We determined the serotypes of 36 human clinical isolates and 64 livestock isolates, performed antimicrobial susceptibility testing against 8 antibiotics, and determined the molecular types of isolated NTS spp. by pulsed field gel electrophoresis (PFGE). In human isolates, S. enteritidis was the most common serotype (17 isolates; 47.2%) and S. typhimurium the second most (8 isolates; 22.2%). In livestock isolates, S. typhimurium was the most common serotype (15 isolates; 23.44%), and S. enteritidis was the second most (14 isolates; 21.88%). Ampicillin and tetracycline resistance were 50% (32/64 isolates) each among broiler-chicken NTS isolates. No human or livestock NTS isolates showed resistance to ciprofloxacin, TMP-SMX, or ceftriaxone. However, 19.4% (7/36) and 46.8% (30/64) of the human and livestock NTS isolates were resistant to nalidixic acid (MIC ≥16 mg/mL), respectively. The presence of the three identical PFGE molecular types from human and broiler-chicken NTS isolates suggests the possibility of transmission from livestock to humans.

Salmonella spp. in patients suffering from enteric fever and food poisoning in Thamar city, Yemen

“…In the Islamic Republic of Iran the most common isolate from patients with enteric fever was Salmonella Typhi (69.6%), while in food poisoning Salmonella Typhimurium (69.0%), was the most common serovar [16]. In non-typhoidal Salmonella food poisoning in Korea, Salmonella Enteritidis (68%) and Salmonella Typhimurium (32%) were the most common serovars, which is similar to the results of our study [17]. This difference between our study and these studies may be due to the difference in geographical region which is known to affect the prevalence of the different Salmonella serovars.…”

Emergence of Extended-Spectrum β-Lactamase (CTX-M-15 and CTX-M-14)-Producing Nontyphoid Salmonella with Reduced Susceptibility to Ciprofloxacin among Food Animals and Humans in Korea

“…Finally, we combined the results of phage typing and molecular typing to produce arbitrary phage-genotype profiles. The combination of phage type and XbaI-AvrII genotype showed that certain common identical profiles were present among NTS strains from food animals as (8). A similar study carried out in Taiwan also reported the transmission of certain common clones of NTS between human and animal sources and reported that these remained in circulation between humans and animals as epidemic strains for years (30).…”

Non-typhoidal Salmonella Gastroenteritis in Al Ain Hospital United Arab Emirates

“…In Yucatan, Mexico, resistance for the treatment of Salmonellosis was observed for Chloramphenicol (21%), Co-Trimaxazole (19.3%) and Ampicillin (17.6%) [20]. While in Korea, all isolates were sensitive to Co-Trimaxazole [21]. The low resistance of our isolates to Ampicillin, Co-Trimaxazole and Chloramphenicol may need a separate study, however, better antibiotic prescribing practices at Al Ain Hospital may have some contribution.…”

“…In Kuwait, all the strains were susceptible to Ciprofloxacin [12]. A recent study from Seoul, Korea showed no resistance to Ciprofloxacin and Ceftriaxone [21]. In Yucatan, Mexico, none of the isolates was resistant to Ciprofloxacin, and only 0.8% resistant to Ceftriaxone [20].…”