Characteristics of malnutrition according to Global Leadership Initiative on Malnutrition criteria in non-surgical patients with inflammatory bowel disease

Huang, Shanshan; Niu, Yang; Liu, Xiaowei; Gu, Zhengye; Huang, Aiyue; Wu, Jiaxue

doi:10.1016/j.nut.2021.111514

Cited by 13 publications

(16 citation statements)

References 27 publications

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“…Most of the other studies were based on patients diagnosed with specific diseases or receiving specific treatments. 28,33,34 Mikkelsen et al assessed the nutrition status of patients with UWL in general practice but did not use the GLIM criteria. 35 In general practice settings, it is not uncommon for a patient to visit the clinic because of UWL.…”

Section: Discussionmentioning

confidence: 99%

“…To our knowledge, this study is the first to select patients based on one phenotypic criterion and describe them using the GLIM criteria. Most of the other studies were based on patients diagnosed with specific diseases or receiving specific treatments 28,33,34 . Mikkelsen et al assessed the nutrition status of patients with UWL in general practice but did not use the GLIM criteria 35 .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The association between GLIM criteria–defined malnutrition and 2‐year unplanned hospital admission in outpatients with unintentional weight loss: A retrospective cohort study

Duan

Zhang

Ren

et al. 2023

J Parenter Enteral Nutr

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Background This study aimed to assess malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and Subjective Global Assessment (SGA) at baseline and determine the GLIM criteria that best predicted unplanned hospitalization in outpatients with unintentional weight loss (UWL). Methods We performed a retrospective cohort study of 257 adult outpatients with UWL. The GLIM criteria and SGA agreement were reported using the Cohen kappa coefficient. Kaplan‐Meier survival curves and adjusted Cox regression analyses were used for survival data. Logistic regression was used for the other correlation analysis. Results This study collected data from 257 patients for 2 years. Based on the GLIM criteria and SGA, malnutrition prevalence was 79.0% and 72.0%, respectively (κ = 0.728, P < 0.001). Using the SGA as a standard, GLIM had a sensitivity of 97.8%, a specificity of 69.4%, a positive predictive value of 89.2%, and a negative predictive value of 92.6%. Malnutrition was associated with higher rates of unplanned hospital admission independent of other prognostic factors (GLIM: hazard ratio [HR]=2.85, 95% CI=1.22–6.68; SGA: HR=2.07, 95% CI=1.13–3.79). Of the five GLIM criteria–related diagnostic combinations, disease burden or inflammation was the most important to predict unplanned hospital admission in multivariable analysis (HR=3.27, 95% CI=2.03–5.28). Conclusion There was good agreement between the GLIM criteria and the SGA. GLIM‐defined malnutrition, as well as all five GLIM criteria–related diagnosis combinations, had the potential to predict unplanned hospital admissions in outpatients with UWL within 2 years.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The association between GLIM criteria–defined malnutrition and 2‐year unplanned hospital admission in outpatients with unintentional weight loss: A retrospective cohort study

Duan

Zhang

Ren

et al. 2023

J Parenter Enteral Nutr

View full text Add to dashboard Cite

show abstract

“…One article defined sarcopenia with the help of total psoas muscle area (TPA) divided by square of the height, with cut-off values < 545 mm 2 /m 2 for males and <385 mm 2 /m 2 for females [23], one article considered that sarcopenia in CD patients was induced by mediators of systemic inflammation and assessed the impact of IFX on muscle volume and muscle strength in correlation with decreasing inflammatory markers IL-6 and C-reactive protein (CRP) [20]. Five articles assessed the effects of malnutrition on IBD patients and correlated it with sarcopenia and frailty [24,26,27,30,32]. One article used AWGS 2019 criteria as the reference standard in diagnosing sarcopenia.…”

Section: Included Studiesmentioning

confidence: 99%

“…Five studies assessed the relationship between malnutrition and IBD and found that malnourished patients were considered susceptible to developing sarcopenia. In older people, the association between sarcopenia and malnutrition was considered as a diagnosis of frailty, and sarcopenic patients were more likely to have a disability than patients without sarcopenia [25][26][27]30,32].…”

Section: Malnutrition Frailty and Disabilitymentioning

confidence: 99%

Diagnostic Criteria and Prognostic Relevance of Sarcopenia in Patients with Inflammatory Bowel Disease—A Systematic Review

Potcovaru

Filip

Neagu

et al. 2023

JCM

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Background: Sarcopenia is a syndrome characteristic in elderly patients and is also associated with a significant proportion of chronic disorders such as inflammatory bowel disease (IBD). In this case, it can lead to a worse prognosis of the disease and a decreased quality of life. Study Aim: This study aims to identify the best ways to diagnose sarcopenia in patients with IBD, establish its impact on the course of the disease, and find preventive methods to counteract the effects of sarcopenia in the outcome of patients with IBD and, therefore, minimize disabilities and increase the health-related quality of life (HRQoL). Material and Methods: A systematic review with the Prospero registration number CRD42023398886 was performed in PubMed and Web of Science databases, evaluating all original articles published in the last 10 years (clinical trials and randomized control trials) that describe sarcopenia and IBD in the human adult population. Results: From the 16 articles that were included, 5 articles defined sarcopenia by the skeletal muscle index (SMI) and reported data regarding its correlation with body composition: BMI; visceral fat (VF); subcutaneous fat (SC); and VF/SC index. Other articles evaluated the link between sarcopenia and the total psoas muscle area, thigh circumference, calf circumference, subjective global assessment, hand grip strength, and appendicular SMI, alongside inflammatory markers such as IL-6 and C-reactive protein, level of disability, malnutrition, frailty, resistance training alone and in combination with whey protein, and infliximab treatment. Discussions and Conclusions: There is a great heterogeneity regarding the assessment criteria and methods used to diagnose sarcopenia due to the variability of population characteristics, both anthropometric and socio-cultural, alongside the high variability in the cut-offs. Therefore, any method which identifies sarcopenia in IBD patients, thus enabling intervention, may provide good results for patient quality of life and outcomes.

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“…Malnutrition is an important and common condition in terms of disease course and response to therapy in inflammatory bowel disease (IBD). 1 Its prevalence ranges between 5 and 75% according to different studies and different patient populations. It is obvious that the nature of IBD and its therapy, either medical or surgical, are potential risk factors for malnutrition.…”

Section: Introductionmentioning

confidence: 99%

Sarcopenia and Its Effect on Inflammatory Bowel Disease

Akpınar¹

2022

J Enterocolitis

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Malnutrition and sarcopenia are common conditions in inflammatory bowel disease. Both Crohn's disease and ulcerative colitis are characterized by chronic inflammation; additionally, strictures and fistulas can be seen in Crohn's disease. These conditions, individually or together, are causative factors for diminished oral intake, micronutrient deficiencies, protein-energy malnutrition, and/or sarcopenia. Malnutrition is considered poor prognostic criteria for inflammatory bowel disease in terms of disease course, hospitalization, need for surgery, and surgical complications. Sarcopenia is a syndrome characterized by progressive skeletal muscle deficiency which can be responsible for higher hospitalization rates, increase in bone fractures, and impairment of immune system functions. It seems that assessment of sarcopenia in patients with inflammatory bowel disease is essential since sarcopenia is considered a poor prognostic factor such as in many other chronic disease. In the last decade, studies investigating sarcopenia in inflammatory bowel disease were markedly increased. According to these studies, sarcopenia is a common condition in inflammatory bowel disease, and it can be classified as a poor prognostic factor for inflammatory bowel disease like malnutrition. Here, we want to review studies in the literature to clarify the frequency of sarcopenia and its potential effects on disease course in inflammatory bowel disease.

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Characteristics of malnutrition according to Global Leadership Initiative on Malnutrition criteria in non-surgical patients with inflammatory bowel disease

Cited by 13 publications

References 27 publications

The association between GLIM criteria–defined malnutrition and 2‐year unplanned hospital admission in outpatients with unintentional weight loss: A retrospective cohort study

The association between GLIM criteria–defined malnutrition and 2‐year unplanned hospital admission in outpatients with unintentional weight loss: A retrospective cohort study

Diagnostic Criteria and Prognostic Relevance of Sarcopenia in Patients with Inflammatory Bowel Disease—A Systematic Review

Sarcopenia and Its Effect on Inflammatory Bowel Disease

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