Characteristics of hemodialysis patient with critical COVID‐19

Abstract

Introduction:The clinical course of hemodialysis patients with COVID-19 still remains unclear.Methods: Thirty-four hemodialysis patients were retrospectively enrolled. Patients were divided according to disease severity, and clinical symptoms and laboratory data at admission were compared. Results:The serum C-reactive protein (CRP) level, D-dimer level, and white blood cell (WBC) count were significantly higher in the group with critical disease than in the group with mild to severe disease (p = 0.005, p = 0.039, and p = 0.045). The serum CRP level exceeded 10 mg/dl within 7 days of clinical onset in all the cases with critical disease. Conclusion:Hemodialysis patients with COVID-19 who have elevated serum CRP and D-dimer levels, and an elevated WBC count at admission and patients with serum CRP levels exceeding 10 mg/dl before day 7 after clinical onset should be carefully monitored for possible progression to critical disease.

Characteristics of the 6th Japanese wave of COVID-19 in hemodialysis patients

“…In addition, these patients also show impaired antiviral immune responses because of their impaired kidney functions. Hemodialysis patients with COVID-19 reportedly have a poor prognosis [5][6][7][8][9]. In the present study, we examined the clinical characteristics of hemodialysis patients with COVID-19 during the 6th wave of infection at our hospital.…”

The prevalence and severity of mental health problems and sexual dysfunction in hemodialysis patients before and during the COVID‐19 pandemic

“…Hemodialysis patients must continue to receive lifesustaining treatment, typically three times per week, while hemodialysis attendance via travel to and from the center entails a close interaction with possible SARS-CoV-2 infected individuals [29,30]. In addition, hemodialysis patients have multiple risk factors for severe COVID-19, as several studies have reported a significantly increased risk of transmission of infection with COVID-19 and a higher mortality rate in hemodialysis patients compared with the general population [8,[31][32][33][34]. In a single center study from Italy among 55 hemodialysis patients infected with COVID-19, the authors reported a mortality rate of 52.0% [31], while data from 25 hemodialysis patients hospitalized with COVID-19 in Turkey revealed that COVID-19 disease has a significantly more severe course and worse prognosis with a mortality rate of 20% in hemodialysis patients [32].…”