Characteristics of endobronchial primitive tumors in children

Eyssartier, E.; Ang, Peck Har; Bonnemaison, E.; Gibertini, I.; Diot, Patrice; Carpentier, E; Chantepîe, A.; Leclair, Marc‐David; Brouard, J.; Boutard, Patrick; Deneuville, E.; Marie‐Cardine, Aude; Lardy, H.

doi:10.1002/ppul.22987

Cited by 32 publications

(48 citation statements)

References 18 publications

(42 reference statements)

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“…The abnormal findings in our study included lobar atelectasis, air-leak syndrome and emphysematous changes due to obstruction. Previous studies commonly showed lobar atelectasis or unilateral overinflation involving the bronchi, especially in patients with bronchial tumors (1011). Simple radiographs of patients with laryngeal tumors had mostly normal findings, although some findings mimicked the radiograph finding of croup.…”

Section: Discussionmentioning

confidence: 99%

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The Different Clinical Aspects of Pediatric Primary Airway Tumors in the Larynx, Trachea, and Bronchi

et al. 2017

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Primary airway tumors are rare in children and no literature reviewed their characteristics each location. We evaluate the clinical characteristics and outcomes of Korean children with primary airway tumors, from the larynx to bronchi. A retrospective chart review of children with primary tumors of the larynx, trachea, and bronchi at Asan Medical Center from January 2000 to July 2016 was conducted. Nineteen children were diagnosed with primary airway tumors of the larynx (47.4%), trachea (10.5%), and bronchi (42.1%). Median follow-up duration was 2.8 years and there were recurrences in 21.1%. Laryngeal tumors were associated with a younger median age at onset (2 months) and diagnosis (4 months), and most were relatively small (median size = 5.3 mm) and symptomatic. Tracheal and bronchial tumors were found in older children (age at onset and diagnosis > 11 years) and large (> 15.0 mm). Most (75%) patients with bronchial tumors were asymptomatic and all the patients with tracheal tumors were symptomatic. This study suggests that we should consider different the locations in primary airway tumor based on the age at onset and diagnosis, initial symptoms or signs, and size of tumor.

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Section: Discussionmentioning

confidence: 99%

“…Yu et al (10) compared the clinical characteristics and outcomes of 35 adults and 19 children with tracheal and bronchial tumors. Eyssartier et al (11) and Roby et al (12) only described the characteristics and outcomes of cases of 12 bronchial and 14 tracheobronchial patients, respectively.…”

Section: Introductionmentioning

confidence: 99%

The Different Clinical Aspects of Pediatric Primary Airway Tumors in the Larynx, Trachea, and Bronchi

et al. 2017

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“…Pulmonary tumors in the pediatric population are rare and account for only 0.2% of all cases of childhood cancer [1]. Carcinoid tumors are malignant neuroendocrine tumors and, together with pleuropulmonary blastomas, make up the most common pediatric pulmonary malignancies [2].…”

Section: Introductionmentioning

confidence: 99%

Endobronchial Carcinoid and Concurrent Carcinoid Syndrome in an Adolescent Female

Cogen

Swanson

Ong

2016

Case Reports in Pediatrics

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Endobronchial carcinoid tumors are the most common intrabronchial tumors in children and adolescents. Common signs and symptoms include persistent cough and wheezing not responsive to bronchodilators, hemoptysis, and recurrent fever. Diagnosis is frequently made by imaging and direct visualization with flexible bronchoscopy; surgery remains the gold standard treatment, and lung-sparing resections should be performed whenever possible. Though carcinoid syndrome—characterized by flushing, palpitations, wheezing, shortness of breath, and diarrhea—has been found in association with adult bronchial carcinoid tumors, to our knowledge only one previous study has reported the presence of carcinoid syndrome in a pediatric patient with an endobronchial carcinoid. Here, we report a case of a 14-year-old girl with chronic cough found to have an endobronchial carcinoid tumor and signs and symptoms consistent with carcinoid syndrome.

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“…The time of presentation is very important as this is the period in which these lesions undergo vascular proliferation and enlarge considerably. [3] Spontaneous resolution is said to occur at about 12 months of age. [4] The diagnosis should be considered in any patient in this age group who presents with hoarseness of voice, recurrent croup and a barking cough.…”

Section: Reviewmentioning

confidence: 99%

Tumours of the chest in children: A review

Niekerk¹,

Parris²,

Campos³

et al. 2016

S Afr Res J

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Tumours of the chest in children constitute an array of pathology and clinical symptomatology. These tumours can be benign or malignant, cystic or solid, primary or as a result of secondary metastases. Collectively, tumours of the chest in children are very rare, the exact incidence of which is largely unknown globally. Non neoplastic lesions of the lung including bronchogenic cysts, sequestrations, congenital pulmonary airway malformations as well as infective and inflammatory disorders are 60 times more common than neoplastic causes.1A tumour of the chest is considerably difficult to diagnose since patients can be asymptomatic for many years before symptoms evolve. Even more so, the symptoms are non-specific and can suggest more common and less sinister pathology.Clinically patients present with a variety of symptoms that depend largely on the location of the tumour. Airway tumours can be symptomatic or can present with chronic cough, wheeze, haemoptysis, atelectasis or persistent pneumonia. Secondary malignant parenchymal tumours are likely to be symptomatic from the primary lesion. Anterior mediastinal tumours can cause compression of the large airways or superior vena caval structures. It stands to reason that the physician needs to have a very high index of suspicion when dealing with these non-specific signs and symptoms.This article provides an approach to tumours of chest and reviews the common aetiology in the different compartments of the chest. The article will focus on common tumours of the airway, lung parenchyma, mediastinum, cardiac and chest wall pathology.

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Characteristics of endobronchial primitive tumors in children

Cited by 32 publications

References 18 publications

The Different Clinical Aspects of Pediatric Primary Airway Tumors in the Larynx, Trachea, and Bronchi

The Different Clinical Aspects of Pediatric Primary Airway Tumors in the Larynx, Trachea, and Bronchi

Endobronchial Carcinoid and Concurrent Carcinoid Syndrome in an Adolescent Female

Tumours of the chest in children: A review

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