Characteristics of COVID-19 positive pregnant patients admitted in a private tertiary hospital and their maternal and neonatal outcomes

Lim, JosephineAlexandra D.; Gonzaga, Z.; Hernandez-Nazal, MarilesR

doi:10.4103/pjog.pjog_16_22

Cited by 1 publication

(2 citation statements)

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“…This finding may reflect the younger age and lower prevalence of comorbidities among pregnant women in our study. Previous reports in the Philippines also showed lower comorbidities in pregnant patients infected with COVID-19 [ 2 , 4 ]. Although pregnant women had a significantly more extended hospital stay, they had shorter ICU admission, shorter ventilator dependence, resolved or improved neurologic symptoms at hospital discharge, and had a lower risk of mortality.…”

Section: Discussionmentioning

confidence: 69%

“…Earlier reports in the Philippines indicated that several pregnant COVID-19 patients were asymptomatic, ranging from 22 to 42% of individuals [ 2 , 3 , 4 ]. Previous studies have also suggested that pregnant women with COVID-19 have a favorable clinical course compared with the nonpregnant population [ 2 , 5 , 6 , 7 , 8 , 9 , 10 ]; however, pre-existing diseases may increase the probability of hospitalization [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Clinical Outcomes of COVID-19 Infection in Pregnant and Nonpregnant Women: Results from The Philippine CORONA Study

et al. 2023

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Objective: Our study determined the association of pregnancy with various clinical outcomes among women with COVID-19 infection. Methods: We conducted a retrospective, cohort, subgroup analysis of the Philippine CORONA Study datasets comparing the clinical/neurological manifestations and outcomes of pregnant and nonpregnant women admitted in 37 Philippine hospitals for COVID-19 infection. Results: We included 2448 women in the analyses (322 pregnant and 2.126 nonpregnant). Logistic regression models showed that crude odds ratio (OR) for mortality (OR 0.26 [95% CI 0.11, 0.66]), respiratory failure [OR 0.37 [95% CI 0.17, 0.80]), need for intensive care (OR 0.39 [95% CI 0.19, 0.80]), and prolonged length of hospital stay (OR 1.73 [95% CI 1.36, 2.19]) among pregnant women were significant. After adjusting for age, disease severity, and new-onset neurological symptoms, only the length of hospital stay remained significant (adjusted OR 1.99 [95% CI 1.56,2.54]). Cox regression models revealed that the unadjusted hazard ratio (HR) for mortality (HR 0.22 [95% CI 0.09, 0.55]) among pregnant women was statistically significant; however, after adjustment, the HR for mortality became nonsignificant. Conclusion: We did not find a significantly increased risk of mortality, respiratory failure, and need for ICU admission in pregnant women compared with nonpregnant women with COVID-19. However, the likelihood of hospital confinement beyond 14 days was twice more likely among pregnant women than nonpregnant women with COVID-19.

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Section: Discussionmentioning

confidence: 69%