Characteristics of Bovine Lymphoma Caused by Bovine Leukemia Virus Infection in Holstein-Friesian Dairy Cattle in Korea

Abstract

However, few studies have been performed on lymphoma, the clinical form of EBL, until now (Lim, 1969;Lee et al., 1982), and the reports on characteristics of lymphoma in the naturally BLV-infected cattle are limited in Korea. It is the purpose of this study to assess the frequency and distribution of lymphoma in the BLV-infected cattle. MATERIALS AND METHODS

Nucleolar Organizer Region Count, PCNA and Ki-67 Indices are Diagnostic Markers of Malignancy and Cell Proliferation Rate in Bovine Lymphosarcoma

“…The present study revealed high incidence in male cattle (75%) than in female (25%) cattle, which was in agreement with the reports of Singh [15,16] in buffaloes. In contrary, Yoon et al [14] observed 100% of the lymphosarcoma cases in female cattle. In the present study, the enlargement was observed mostly in lymph nodes followed by the visceral organs, as observed by Yoon et al [14] Sabareeswaran et al [17] and Anusha et al [18] reported cases of ocular lymphoma, pulmonary lymphoma, uterine lymphosarcoma respectively in buffaloes.…”

“…In contrary, Yoon et al [14] observed 100% of the lymphosarcoma cases in female cattle. In the present study, the enlargement was observed mostly in lymph nodes followed by the visceral organs, as observed by Yoon et al [14] Sabareeswaran et al [17] and Anusha et al [18] reported cases of ocular lymphoma, pulmonary lymphoma, uterine lymphosarcoma respectively in buffaloes. Lymph might be the main route of metastasis to different organs as mentioned by Yoon et al [14].…”

“…This difference in incidence might be due to the detection of affected animals only during slaughter [14]. All the affected animals were cattle.…”

“…Grossly, the enlargement was noticed in prescapular and precrural lymph nodes in calves and there was enlargement and fusion of mesenteric lymph nodes in the cow. The affected organs were soft, fleshy, greyish white and on cut section, the lymph nodes showed bulging and a homogenous pale appearance with no demarcation between cortex and medulla [14,15,[19][20][21]. Impression smears collected from affected lymph nodes and organs like heart, lung, liver and kidney revealed numerous cells which included lymphocytes, prolymphocytes and lymphoblasts.…”

Seroprevalencia De Leucosis Enzoótica Bovina en Animales Entre 6 a 24 Meses en Las Provincias De Manabí, Pichincha Y Chimborazo - Ecuador

“…Los insectos hematófagos actúan como vectores de la enfermedad, y a pesar de que no es muy habitual la transmisión vertical, intrauterina o calostral (OIE, 2011) podría provocar en un predio infectado un mayor porcentaje de animales enfermos, con las consecuentes pérdidas econó-micas para el productor. En estudios realizados en Corea en 30 animales enfermos con LEB, se observaron tejidos neoplásicos en los ganglios linfáticos de todos los animales; también se observaron nódu-los en intestino (96,4 %), corazón (88,9 %), estóma-go (73,1 %) y diafragma (62,5 %), sugiriendo que se produce metástasis de la enfermedad (Yoon et al, 2005). Por lo tanto, es necesario un mayor control de LEB con la finalidad de monitorear y dar seguimiento a los animales, principalmente en los más jó-venes, ya que representan mayor riesgo para la producción.…”