Characteristics of allergen profile, sensitization patterns and Allergic Rhinitis in SouthEast Asia

Abstract

Purpose of reviewTo highlight the characteristics of allergic rhinitis, local allergic rhinitis (LAR), and importance of allergens in Southeast Asian countries. Recent findingsThe Asia-Pacific region is very diverse with disparities in the epidemiological data between countries as well as in the unmet needs. The prevalence of allergic rhinitis has markedly increased in the past decades, with a high variation between countries, ranging from 4.5-80.3%. In terms of LAR, the reported prevalence in Southeast Asia is similar to that of other Asian countries (3.7-24.9%) but lower than that in western countries. House dust mites, cockroach, pollens, and molds are major allergens that are known triggers for of allergic rhinitis in this region, whereas the association with helminth infection requires further investigation.

Cell division cycle 42 reflects disease risk, symptoms, Th1/Th2 disproportion, and its short‐term variation indicates symptom amelioration after treatment in allergic rhinitis patients

“…Allergic rhinitis (AR) is an allergic reaction in the nasal mucosa to inhaled allergens, which is associated with several physiological procedures such as the production of allergen‐specific immunoglobulin E (IgE), activation of T‐helper (Th) cells, and chronic inflammation 1,2 . Globally, AR is a prevalent disease with steadily increasing incidence in low‐ and middle‐income countries, partly due to the increasing level of pollutants such as traffic waste and particulate matter 2.5 (PM2.5) 3–5 . The current medical management for AR mainly includes antihistamines, intranasal corticosteroids, and allergen‐specific immunotherapy; however, these treatments merely relieve the symptoms of AR 6–8 .…”

Validity and Reliability of The Indonesian Version of Patient Allergic Rhinitis Questionnaire and Allergic Rhinitis Prevalence in A Class Of 2018-2019 Medical Students of Universitas Padjadjaran, Indonesia

“…3 In the Asia-Pacific region, the prevalence of AR is ranging between 4.5-80.3%. 5 Meanwhile, the prevalence of AR in Indonesia is not known for certain because there is no national data on this matter, but there was a study on a class of 2010 medical students of Padjadjaran University which showed that the prevalence of AR was 38.2%. 6 Allergic rhinitis can decrease quality of life by impairing cognitive function and sleep and also causing fatigue and irritability.…”