Characteristics and osteoconductivity of three different plasma-sprayed hydroxyapatite coatings

Wang, B.C.; Chang, Edward F.; Yang, Chuanfang; Tu, D.; Tsai, Chung-En

doi:10.1016/0257-8972(93)90181-m

Cited by 56 publications

(28 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As shown in Figs 5 and 7, the evidence of direct bone-PSHA coating contact was observed, being consistent with studies where osseointegration of HA coating was reported [13][14][15][16][17][18][19]. This led to the provision of strong implant-to-bone fixation.…”

Section: Discussionsupporting

confidence: 75%

“…More recently, the uses of plasma-sprayed hydroxyapatite (HA) coatings, in comparison with porous coating, were documented to reveal many advantages. These included the formation of chemical bonding at the HA/bone interface [10,12], the promotion of normal bone formed along the HA layer [13][14][15][16][17][18][19], and the protection of surrounding bone against metal-ion release from a metal prosthesis [20]. Therefore, HA-coated metal implants seem promising for application in orthopaedic surgery.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mechanical and histological evaluations of cobalt-chromium alloy and hydroxyapatite plasma-sprayed coatings in bone

Yang

Wang

Chang

et al. 1996

J Mater Sci: Mater Med

Self Cite

View full text Add to dashboard Cite

This study evaluated the mechanical and histological behavior of cobalt-chromium (CoCr) alloy and hydroxyapatite (HA) plasma-sprayed coatings in canine cortical bone after 6 and 12 weeks of implantation, using CoCr alloy as the substrate. The substrate was bond-coated with microtextured CoCr alloy coating to ensure adherence between the substrate and top coats. A macrotextured CoCr alloy top coat with surface roughness Ra =34.25 _+ 5.50 I~m was produced to create suitable pores ranging from 25 t~m to 200 I~m for bone ingrowth. For HA top coat, a relatively smooth surface (Ra= 15.14+3.21 gm) was prepared for bone apposition. Shear testing of bone/implant interfaces showed that the CoCr alloy top coat exhibited significantly lower (p < 0.01) mean shear strength than the HA top coat at each time interval. The maximum shear strength was 10.884-0.38 MPa for HA-coated implants 12 weeks post-implantation. After histological evaluations, substantial differences in the extent of new bone formation and the types of implant/bone contact were found between two kinds of implants. Direct bone-to-HA coating contact was consistently observed, while a layer of fibrous tissue intervening at the bone CoCr alloy coating interface was found. Occasionally, partial dissolution of HA coating was seen after 12 weeks of implantation. The results of this study suggested that plasma-sprayed macrotextured CoCr coatings may not be an effective alternative for biological fixation.

show abstract

Section: Discussionsupporting

confidence: 75%

Section: Introductionmentioning

confidence: 99%

Mechanical and histological evaluations of cobalt-chromium alloy and hydroxyapatite plasma-sprayed coatings in bone

Yang

Wang

Chang

et al. 1996

J Mater Sci: Mater Med

Self Cite

View full text Add to dashboard Cite

show abstract

“…However, it is difficult to get the ideal HAC by the plasma-sprayed process. In our previous study, 29 the HAC prepared by high enthalpy condition would produce the high mechanical properties and denser microstructure, but the high power condition would induce the formation of amorphous HA and impurity phase. To acquire the ideal HAC, the hydrothermal treatment is adopted to improve the microstructure, bonding strength, crystallinity, and phase composition of HAC (Table VI).…”

Section: Discussionmentioning

confidence: 98%

In vitro and in vivo biological responses of plasma‐sprayed hydroxyapatite coatings with posthydrothermal treatment

Lee

Yang

Chen

et al. 2007

J Biomedical Materials Res

View full text Add to dashboard Cite

This study was undertaken to evaluate the effect of post-hydrothermal treatment on the biological responses of the plasma-sprayed hydroxyapatite (HA)-coated Ti-6Al-4V implant system both in vitro and in vivo. After hydrothermal treatment, the HA coating (HAC) shows the high mechanical strength and indices-of-crystallinity, denser microstructure, lower concentrations of amorphous and impurity phases, when compared with the as-sprayed HAC. The in vitro cell-culture studies, using UMR106 osteoblast-like cell, demonstrated no signifiacnt cell growth on both surface of as-sprayed and hydrothermal-treated HACs during 10-day culture. The in vivo studies, using the transcortical implant model in the femora of goats, evaluated the histological responses of two coatings. After 6 week of implantation, using backscattered electron images, no substantial histological variations in the extents of new bone apposition and new bone healing between the two HACs were observed. However, the as-sprayed HAC, owing to the dissolution induced the granular particles dissociated from the HAC, showed the statically lower extent of new bone apposition than hydrothermal-treated HAC at 12 weeks. The results suggest that hydrothermal treatment could be used to improve the mechanical strength, crystallinity, and phase composition of HAC, which are important factors of long-term fixation and stability of implant. Besides, the treated HAC could also achieve the initial fixation of implant in clinical use.

show abstract

“…Adherence of the HA coatings under these extreme bending conditions is not consistent with the low bond strengths reported by tensile-pull tests. 20,21,23,25,26 Effects of Cyclic Bending (in Air). Testing at deflections of 1.3 and 1.8 mm induced maximum bending stresses below the fatigue limit of CP Ti.…”

Section: Effects Of Substrate Low-cycle Fatigue Failure (In Air)mentioning

confidence: 99%

Effects of cyclic bending and physiological solution on plasma-sprayed hydroxylapatite coatings of varying crystallinity

Haynes

Rigney

Janowski

1999

J. Biomed. Mater. Res.

View full text Add to dashboard Cite

This study investigated the effects of cyclic bending stress levels and testing in simulated physiological solutions or air on the integrity of plasma-sprayed hydroxylapatite (HA) coatings of two different crystallinities. Hydroxylapatite-coated commercially pure (CP) Ti rods were evaluated by immersion testing in Hank's Balanced Salt Solution (HBSS) and by rotating bending in air and HBSS. Static immersion testing of nonstressed specimens resulted in significant microcracking of coating surfaces after 42 days. Specimens cyclically tested at bending stresses above the yield strength of Ti experienced low cycle fatigue failure of the Ti substrates prior to spallation of the HA coatings. Coatings tested at 1 x 10(6) cycles with interface bending stresses of 180 MPa displayed increased surface microcracking, but no bulk coating spallation. Coatings cycled in HBSS displayed greater amounts of microcracking and surface alteration than samples cycled in air. There was no apparent relation between HA crystallinity and mechanical integrity under cyclic bending stresses.

show abstract

Characteristics and osteoconductivity of three different plasma-sprayed hydroxyapatite coatings

Cited by 56 publications

References 21 publications

Mechanical and histological evaluations of cobalt-chromium alloy and hydroxyapatite plasma-sprayed coatings in bone

Mechanical and histological evaluations of cobalt-chromium alloy and hydroxyapatite plasma-sprayed coatings in bone

In vitro and in vivo biological responses of plasma‐sprayed hydroxyapatite coatings with posthydrothermal treatment

Effects of cyclic bending and physiological solution on plasma-sprayed hydroxylapatite coatings of varying crystallinity

Contact Info

Product

Resources

About