Characteristic sonographic signs of hepatic fatty infiltration

Quinn, Stephen F.; Gosink, B B

doi:10.2214/ajr.145.4.753

Cited by 120 publications

(71 citation statements)

References 9 publications

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“…However, this does not seem to be a good method, because the liver is metabolically ve r y a c t ive a n d i t s e ch o g e n i c i t y e x h i b i t s h i g h variance [15,16] . The concurrence of fatty pancreas and fatty liver on sonography was very high in our data (67.9%).…”

Section: Discussionmentioning

confidence: 99%

Clinical implications of fatty pancreas: Correlations between fatty pancreas and metabolic syndrome

Lee¹,

Kim²,

Jun³

et al. 2009

WJG

241

277

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AIM:To investigate the clinical implications of lipid deposition in the pancreas (fatty pancreas). METHODS:The subjects of this study were 293 patients who had undergone abdominal computed tomography (CT) and sonography. Fatty pancreas was diagnosed by sonographic findings and subdivided into mild, moderate, and severe fatty pancreas groups comparing to the retroperitoneal fat echogenicity. RESULTS:Fatty pancreas was associated with higher levels for visceral fat, waist circumference, aspartate aminotransferase (AST), alanine aminotransferase (ALT), total cholesterol, triglyceride, high density lipoprotein, free fatty acid, γ-GTP, insulin, and the homeostasis model assessment of insulin resistance (HOMA-IR) than the control group (P < 0.05). HOMA-IR, visceral fat, triglyceride, and ALT also tended to increase with the degree of fat deposition in the pancreas on sonography. In a multivariate logistic regression analysis, HOMA-IR, visceral fat, and ALT level were independently related to fatty pancreas after adjustment for age, body mass index, and lipid profile. The incidence of metabolic syndrome in the fatty pancreas group was significantly higher than in the control group, and the numbers of metabolic syndrome parameters were significantly higher in the fatty pancreas group (P < 0.05).CONCLUSION: Sonographic fatty pancrease showed higher insulin resistance, visceral fat area, triglyceride, and ALT levels than normal pancreases. Fatty pancreas also showed a strong correlation with metabolic syndrome.

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Section: Discussionmentioning

confidence: 99%

Clinical implications of fatty pancreas: Correlations between fatty pancreas and metabolic syndrome

Lee¹,

Kim²,

Jun³

et al. 2009

WJG

241

277

View full text Add to dashboard Cite

show abstract

“…Moreover, liver ultrasonography has proven to be a sensitive, accurate and convenient diagnostic tool in detecting steatosis. Its sensitivity ranges from 60-94% and its specificity from 84-95% (16,29).…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis of NAFLD was based on increased liver echotexture on ultrasonography (Siemens Antares [Erlangen, Germany]) compared with the kidneys, vascular blurring and deep attenuation (16). Fat infiltration in the liver was described in three ultrasonographic stages using published criteria (17,18).…”

Section: Diagnosis Of Nafldmentioning

confidence: 99%

A new risk factor for the development of non-alcoholic fatty liver disease: HLA complex genes

Celıkbılek

Şelçuk²,

Yilmaz³

2011

Turk J Gastroenterol

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(33 erkek, ortalama yafl: 53,8 [yafl aral›¤›, 32-77]) ve ultrasonografisi normal 50 verici aday› kontrol grubu olarak al›nd› (20 erkek, ortalama yafl: 44,6 [yafl aral›¤›, 26-71] (33 male, median age: 53.8 [range, 32-77 years]) by means of ultrasonography data, and 50 individuals, whose ultrasonography data did not show hepatosteatosis, comprised the control group (20 male, median age: 44.6 [range, 26-71 years]

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“…Subjects with fatty liver on ultrasonographic examination, diagnosed by standard criteria, 20 were designated as having probable NAFL (n ¼ 189).…”

Section: Methodsmentioning

confidence: 99%

Nonobese population in a developing country has a high prevalence of nonalcoholic fatty liver and significant liver disease

et al. 2010

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There is a paucity of community-based epidemiological data on nonalcoholic fatty liver (NAFL) among nonaffluent populations in developing countries. Available studies are radiological and/or biochemical and lack histological assessment, limiting their strength. We conducted a prospective epidemiological study comprising a 1:3 subsample of all adult (>18 years) inhabitants of a rural administrative unit of West Bengal, India. Subjects positive for hepatitis B virus and/or hepatitis C virus infection and consuming any amount of alcohol were excluded. Diagnosis of NAFL was by dual radiological screening protocol consisting of ultrasonographic and computed tomographic examination of the liver. Transient elastographic examination and liver biopsy were performed in a subset to identify significant liver disease. The risk factors of having NAFL were analyzed. A total of 1,911 individuals were analyzed, 7% of whom were overweight and 11% of whom had abdominal obesity. The prevalence of NAFL, NAFL with elevated alanine aminotransferase, and cryptogenic cirrhosis was 8.7%, 2.3%, and 0.2%, respectively. Seventy-five percent of NAFL subjects had a body mass index (BMI) <25 kg/m 2 , and 54% were neither overweight nor had abdominal obesity. The subjects with the highest risk of having NAFL were those with a BMI >25 kg/m 2 (odds ratio 4.3, 95% confidence interval 1.6-11.5). Abdominal obesity, dysglycemia (fasting plasma glucose >100 mg/dL or elevated homeostatic model assessment of insulin resistance), and higher income were the other risk factors. Even having a normal BMI (18.5-24.9 kg/m 2 ) was associated with a 2-fold increased risk of NAFL versus those with a BMI <18.5 kg/m 2

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Characteristic sonographic signs of hepatic fatty infiltration

Cited by 120 publications

References 9 publications

Clinical implications of fatty pancreas: Correlations between fatty pancreas and metabolic syndrome

Clinical implications of fatty pancreas: Correlations between fatty pancreas and metabolic syndrome

A new risk factor for the development of non-alcoholic fatty liver disease: HLA complex genes

Nonobese population in a developing country has a high prevalence of nonalcoholic fatty liver and significant liver disease

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