Characterisation of Diarylheptanoid‐ and Flavonoid‐type Phenolics in Corylus avellana L. Leaves and Bark by HPLC/DAD–ESI/MS

Abstract

The improved HPLC/DAD-ESI/MS method was successfully utilised for the characterisation and quantitation of the phenolic compounds in C. avellana bark and leaves extracts.

Quali-quantitative analysis of the phenolic fraction of the flowers of Corylus avellana, source of the Italian PGI product “Nocciola di Giffoni”: Isolation of antioxidant diarylheptanoids

“…To the authors' knowledge the only phytochemical investigation carried out on C. avellana leaves and bark collected in Hungary led to isolation of linear diarylheptanoids (Riethmuller et al, 2013). Noteworthy, this study along with our previous investigations on the leaves of C. avellana cultivar "Tonda di Giffoni", confirm this cultivar labeled with the PGI mark as a source of cyclized diarylheptanoids.…”

“…Antioxidant activity has been reported for C. avellana byproducts such as skin, hard shell, green leafy cover, and tree leaf (Alasalvar et al, 2009a(Alasalvar et al, , 2006(Alasalvar et al, , 2009bShahidi et al, 2007). Previous phytochemical investigation on by-products of C. avellana reported the presence of diarylheptanoids and flavonoids in the leaves and barks (Amaral et al, 2005;Riethmuller et al, 2013). Moreover, the influence of cultivar, geographical origin and ripening stage on phenolic composition of hazelnut leaves was explored (Amaral et al, 2010).…”

Evaluation of Radical Scavenging Activity ofSempervivum tectorumandCorylus avellanaExtracts with Different Phenolic Composition

“…2. In our previous work[24] LC-MS/MS evaluation of C. avellana leaf extracts revealed the presence of diarylheptanoid glycosides and aglycones including hirsutenone. In addition, flavonol glycosides: kaempferol, quercetin and myricetin, principally in the form of monosides were detected.…”

“…monosaccharides). Additionally, the differences between radical scavenging activity of S. tectorum and C. avellana may be explained by the presence of diarylheptanoid glycosides and aglycones in hazel extracts [24]. A hirsutenone standard showed the highest antioxidant activity in the applied in vitro tests, thus the contribution of diarylheptanoid compounds to the antioxidant activity of hazel extracts should be taken into consideration.…”

Phenolic profiling of various olive bark-types and leaves: HPLC–ESI/MS study

“…With TOF-MS, the elemental composition and using QQQ-MS from the fragmentation pattern other important structural information can be provided. From these methods qualitative and quantitative information can also be obtained from a variety of matrices as well (Fu et al, 2010;Riethmüller et al, 2013).…”