Chapter 5 Metabolic modifiers in animal nutrition: potential benefits and risks

Murdoch, Gordon K.; Okine, E. K.; Christopherson, R. J.

doi:10.1016/s1877-1823(09)70092-x

Cited by 5 publications

(4 citation statements)

References 242 publications

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“…Supplemental Cr requirements of ruminants have not been established (NRC 1997(NRC , 2007Murdoch et al 2006). In the present study, the average consumption of supplemental Cr per kg of BW was 0.019 (range from 0.009 to 0.028).…”

Section: Itemmentioning

confidence: 52%

Effects of feeding different levels of chromium-enriched live yeast in hairy lambs fed a corn-based diet: effects on growth performance, dietary energetics, carcass traits and visceral organ mass

et al. 2013

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Forty Pelibuey × Kathdin lambs (35.5 ± 0.4 kg) were used in a 56-day feeding experiment to assess the effects of feeding different levels of chromium-enriched live yeast (Cr-YC) on growth performance, dietary energetics, carcass traits and visceral organ mass. The Cr-YC source contained 5.5 × 109 colony forming units (CFU) and 0.40 mg of Cr per gram. Treatments consisted of a dry rolled corn-based finishing diet supplemented with 0, 1, 2 or 3 g Cr-YC/lamb.day. Total daily dosages were: 5.5 × 109 CFU and 0.4 mg; 1.1 × 1010 CFU and 0.8 mg Cr, and 1.65 × 1010 CFU and 1.2 mg Cr for supplementation levels of 1, 2 or 3 g Cr-YC/lamb.day, respectively. There were no treatments effects on dry matter intake. As the level of Cr-YC supplementation increased, average daily gain, gain to feed and dietary net energy were linearly increased, and observed/expected dry matter intake was linearly decreased. Chromium-enriched live yeast supplementation increased empty bodyweight (EBW), gastrointestinal fill and full viscera weight, but did not influence organ weights as a proportion of EBW (g/kg EBW). Cr-YC level did not affect carcass length, backfat thickness, kidney, pelvic and heart fat or body wall thickness, but increased hot carcass weight and longissimus muscle area. In general, treatment effects on percentage yield of wholesale cuts (tissue weight as a percentage of cold carcass weight) were small. However, Cr-YC decreased percentage flank. Chromium-enriched yeast supplementation enhances growth rate, longissimus muscle area, and dietary energetic efficiency in finishing feedlot lambs.

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Section: Itemmentioning

confidence: 52%

Effects of feeding different levels of chromium-enriched live yeast in hairy lambs fed a corn-based diet: effects on growth performance, dietary energetics, carcass traits and visceral organ mass

et al. 2013

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“…1 Experimental diets: (C) Control (basal diets), (F) Experimental diet containing 5% (DM basis) protected Soybean fat, (S) basal diet containing 4mg/Kg of DMI Salbutamol (beta agonist), (FS) Experimental diet containing 5% (DM basis) protected Soybean fat and 4mg/Kg of DMI Salbutamol (beta agonist); SE= standard error of the mean Shahneh et al (2002). The response to beta agonists varies with animal species, dose and duration (Zare Shahneh et al, 2001;Moody et al (2000), absorption and half-life in body tissue and fluids (Murdoch et al, 2006). In some studies, feed intake decreased due to the effects of beta agonist administration (Mersmann, 1989;Ricks et al, 1984).…”

Section: Discussionmentioning

confidence: 99%

Effect of feeding protected soybean fat supplement and Salbutamol administration on growth performance, nutrient digestibility and carcass characteristics of Iranian Bahmaei feedlot lambs

2016

Res. Opin. Anim. Vet. Sci.

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This study was conducted to evaluate the effect of feeding protected soybean fat and beta-adrenergic agonist Salbutamol on growth performance, nutrients digestibility and carcass characteristics of Iranian Bahmaei feedlot lambs. Twenty male lambs (mean age 90±7 days, mean weight of 29±1.7 kg) were used in a completely randomized design with four treatments (five replicates per treatment) for 80 days. The treatments were: Control (basal diet), F, experimental diet containing 5% protected soybean fat supplement, S, basal diet plus Salbutamol (4 mg/kg of DMI) and FS, experimental diet containing 5% protected soybean fat supplement and administration of Salbutamol (4 mg/kg of DMI). Treatments were similar in terms of energy, protein, NDF contents and forage to concentrate ratio. At the end of the experiment, the results showed that although feeding fat supplement increased fat and ash digestibility, but had no significant effect on body weight change, average daily gain and feed conversion ratio, DM, OM, NDF and ADF digestibility. Salbutamol did not affect lamb performance and nutrient digestibility however, improved carcass characteristics by increasing weight and percentage of thigh, shoulders, carcass without fat tail and decreased fat tail weight and percentage. Simultaneous use of fat supplement and beta agonist Salbutamol significantly increased weight and percentage of carcass tail fat and reduced carcass without tail fat weight compared to the control (P<0.05). Carcass weight and visceral components were not affected by treatments (P>0.05). Therefore, based on the results of this study, administration of Salbutamol (4 mg/kg of DMI) is recommended to improve carcass characteristics but simultaneous use of protected supplemental fat and beta agonist Salbutamol is not recommended. Keywords: Carcass characteristics, Lambs, Performance, Protected fat, SalbutamolTo cite this article: Forouzmand M, H Ghasemi and E Rowghani, 2016. Effect of feeding protected soybean fat supplement and Salbutamol administration on growth performance, nutrient digestibility and carcass characteristics of Iranian Bahmaei feedlot lambs. Res. Opin. Anim. Vet. Sci., 6(1): 7-12.

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“…Emerging research has demonstrated that TBA and E2 may interact with the polyamine biosynthetic pathway [ 23 , 24 , 25 ]. Polyamines, including putrescine (PUT), spermidine (SPD), and spermine (SPE), are important for normal cell growth and differentiation [ 26 , 27 , 28 , 29 , 30 , 31 ]. Polyamines are orally active, and found in relatively high concentrations in common feedstuffs, such as silage [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

“…Polyamines, including putrescine (PUT), spermidine (SPD), and spermine (SPE), are important for normal cell growth and differentiation [ 26 , 27 , 28 , 29 , 30 , 31 ]. Polyamines are orally active, and found in relatively high concentrations in common feedstuffs, such as silage [ 29 ]. Research shows that when BSCs are treated with polyamines or polyamine precursors, proliferation rates increase [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Polyamine Precursors, Polyamines, and Steroid Hormones on Temporal Messenger RNA Abundance in Bovine Satellite Cells Induced to Differentiate

Reichhardt

Okamoto

Motsinger

et al. 2021

Animals

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Emerging research suggests that hormones found in anabolic implants interact with polyamine biosynthesis. The objective of this study was to determine the effects of steroidal hormones, polyamines and polyamine precursors on bovine satellite cell (BSC) differentiation and polyamine biosynthesis temporally. Primary BSCs were induced to differentiate in 3% horse serum (CON) and treated with 10 nM trenbolone acetate (TBA), 10 nM estradiol (E2), 10 nM TBA and 10 nM E2, 10 mM methionine, 8 mM ornithine, 2 mM putrescine, 1.5 mM spermidine, or 0.5 mM spermine. Total mRNA was isolated 0, 2, 4, 8, 12, 24, and 48 h post-treatment. Abundance of mRNA for genes associated with induction of BSC differentiation: paired box transcription factor 7, myogenic factor 5, and myogenic differentiation factor 1 and genes in the polyamine biosynthesis pathway: ornithine decarboxylase and S-adenosylmethionine—were analyzed. Overall, steroidal hormones did not impact (p > 0.05) mRNA abundance of genes involved in BSC differentiation, but did alter (p = 0.04) abundance of genes involved in polyamine biosynthesis. Polyamine precursors influenced (p < 0.05) mRNA of genes involved in BSC differentiation. These results indicate that polyamine precursors and polyamines impact BSC differentiation and abundance of mRNA involved in polyamine biosynthesis, while steroidal hormones altered the mRNA involved in polyamine biosynthesis.

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Chapter 5 Metabolic modifiers in animal nutrition: potential benefits and risks

Cited by 5 publications

References 242 publications

Effects of feeding different levels of chromium-enriched live yeast in hairy lambs fed a corn-based diet: effects on growth performance, dietary energetics, carcass traits and visceral organ mass

Effects of feeding different levels of chromium-enriched live yeast in hairy lambs fed a corn-based diet: effects on growth performance, dietary energetics, carcass traits and visceral organ mass

Effect of feeding protected soybean fat supplement and Salbutamol administration on growth performance, nutrient digestibility and carcass characteristics of Iranian Bahmaei feedlot lambs

The Impact of Polyamine Precursors, Polyamines, and Steroid Hormones on Temporal Messenger RNA Abundance in Bovine Satellite Cells Induced to Differentiate

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