Chapter 4.4. Adsorption and partition chromatography

Colloidal tectonics for tandem synergistic Pickering interfacial catalysis: oxidative cleavage of cyclohexene oxide into adipic acid

“…The binding of n -heptane and di- n -butyl ether with [C 12 ] 3 [PW 12 O 40 ] NPs is expected to reduce the [C 18 /SO 3 H]@SiO 2 /[C 12 ] 3 [PW 12 O 40 ] interaction. The results indicate that the most hydrophobic solvent ( n -heptane) provides a stronger inhibitory effect due to easier penetration into the [C 12 ] 3 [PW 12 O 40 ] NPs in agreement with the eluotropic series 29. To gain more insight into the attractive interactions between the NPs, an experiment was performed for the [C 8 /SO 3 H]@SiO 2 /[C 12 ] 3 [PW 12 O 40 ] system (entry 10).…”

Determination of MLN0128, an investigational antineoplastic agent, in human plasma by LC–MS/MS

“…Because both MLN0128 and STK040263 are amine derivatives, they have tendency to adsorb on the silica solid support. The use of ammonium formate (10.0 m m at pH 2.8) as a component of the mobile phase not only promotes the formation of protonated analytes, but also dynamically competes with the analyte and the IS to prevent chemical tailing on the column (Hansen, Helboa, & Lund, ; McDowall, Pearce, & Murkitt, ). Furthermore, for achieving a proper solvent strength and selectivity, a mixture of methanol and acetonitrile at a ratio of 85:15 ( v /v) was used as another component of the mobile phase for rapid and efficient separation of the analyte and the IS.…”

“…As shown in Figure 1 The mass spectra of precursor and product ions of MLN0128 and STK040263. Experimental conditions were the same as those described in the section 'Tandem mass spectrometry' chemical tailing on the column (Hansen, Helboa, & Lund, 1984;McDowall, Pearce, & Murkitt, 1989…”