Chapter 2 Frailty concepts

Arai, Hidenori; Kozaki, Koichi; Kuzuya, Masafumi; Matsui, Yasumoto; Satake, Shosuke

doi:10.1111/ggi.13831

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…Together, physical and cognitive impairment is a strong prognostic factor for mortality in patients with diabetes [33]; therefore, frailty and cognitive function should be considered in diabetes care for older adults. Based on the above, the concept of cognitive frailty, which combines physical frailty with cognitive impairment that has not yet led to dementia, has been proposed [34]. Albeit multifactorial, frailty and cognitive impairment share a common etiology; therefore, cognitive frailty is an important concept that should be considered in the prevention of dementia.…”

Section: Interaction Between Frailty and Cognitive Impairmentmentioning

confidence: 99%

Nutrition Management in Older Adults with Diabetes: A Review on the Importance of Shifting Prevention Strategies from Metabolic Syndrome to Frailty

et al. 2020

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The increasing prevalence of older adults with diabetes has become a major social burden. Diabetes, frailty, and cognitive dysfunction are closely related to the mechanisms of aging. Insulin resistance, arteriosclerosis, chronic inflammation, oxidative stress, and mitochondrial dysfunction may be common mechanisms shared by frailty and cognitive impairment. Hyperglycemia, hypoglycemia, obesity, vascular factors, physical inactivity, and malnutrition are important risk factors for cognitive impairment and frailty in older adults with diabetes. The impact of nutrients on health outcomes varies with age; thus, shifting diet therapy strategies from the treatment of obesity/metabolic syndrome to frailty prevention may be necessary in patients with diabetes who are over 75 years of age, have frailty or sarcopenia, and experience malnutrition. For the prevention of frailty, optimal energy intake, sufficient protein and vitamin intake, and healthy dietary patterns should be recommended. The treatment of diabetes after middle age should include the awareness of proper glycemic control aimed at extending healthy life expectancy with proper nutrition, exercise, and social connectivity. Nutritional therapy in combination with exercise, optimal glycemic and metabolic control, and social participation/support for frailty prevention can extend healthy life expectancy and maintain quality of life in older adults with diabetes mellitus.

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Section: Interaction Between Frailty and Cognitive Impairmentmentioning

confidence: 99%