Chapter 12: Epidemiology of Methicillin Resistant Staphylococcus Aureus Bacteraemia Amongst Patients Receiving Dialysis for Established Renal Failure in England in 2008: a joint report from the UK Renal Registry and the Health Protection Agency

Abstract

Background: From April 2007, all centres providing renal replacement therapy in England were asked to provide additional data on patients with Methicillin Resistant Staphylococcus aureus (MRSA) bacteraemia using a secure web based system established to capture data for the mandatory surveillance of MRSA bacteramia. Results: From April 2008 until March 2009 171 discrete episodes of MRSA bacteraemia were identified from the Health Protection Agency database as being potentially associated with patients in established renal failure (ERF) requiring dialysis. Of 171 records, 18 records were rejected by renal centres as not being associated with patients on dialysis or as being duplicates of other records. Following data validation by centres, 139 patients had vascular access documented (no episodes of bacteraemia were recorded amongst patients receiving peritoneal dialysis). Of these patients, 30.2% were utilising an arteriovenous fistula or graft and 69.8% were dialysing on a nontunnelled or tunnelled venous catheter. Two of the patients on arteriovenous fistulae had used venous catheters in the prior 28 days. Eleven patients had more than one episode in the year and accounted for 30 (20%) of the episodes of MRSA bacteraemia. Overall there was a reduction of 22% in episodes from the previous year. The median centre-specific rate of MRSA bacteraemia was 0.64 (range 0–3.49) episodes per 100 haemodialysis patients per year, and 0.55 (range 0–2.89) episodes per 100 dialysis (haemodialysis and peritoneal dialysis combined) patients per year. Conclusions: The rate of MRSA bacteraemia in patients requiring long term dialysis continues to fall within the prevalent dialysis population in England, but there is still marked variation in centrespecific rates.

UK Renal Registry 16th Annual Report: Chapter 15 Epidemiology of Reported Infections amongst Patients Receiving Dialysis for Established Renal Failure in England from May 2011 to April 2012: a Joint Report from Public Health England and the UK Renal Registry

“…The dataset included dialysis modality, type of dialysis access and use of non-tunnelled venous catheters within the preceding 28 days. The previous report confirmed that while dialysis patients remain at increased risk from MRSA there has been a continued year on year decline in the number of bacteraemias [3]. The report also provided the first experience of MSSA BSI reporting for the first six months of mandatory surveillance.…”

UK Renal Registry 18th Annual Report: Chapter 12 Epidemiology of Reported Infections amongst Patients Receiving Dialysis for Established Renal Failure in England 2013 to 2014: a Joint Report from Public Health England and the UK Renal Registry

“…It should be noted that although reporting is mandatory for these data collections (MRSA, MSSA and E. coli BSI and CDI), completion of documentation of information relating to renal failure is currently conducted on a voluntary basis depending on the data entry policy within the reporting NHS acute Trust. The methods used for the reporting of infections to Public Health England (PHE) have been described in previous UKRR reports (see appendix 1) [4,5].…”

UK Renal Registry 17th Annual Report: Chapter 12 Epidemiology of Reported Infections amongst Patients Receiving Dialysis for Established Renal Failure in England in 2012 to 2013: a Joint Report from Public Health England and the UK Renal Registry

“…The methods used have been described in previous registry reports (see appendix 1) [4,5]. Briefly, three stages of data collection and validation were undertaken by Public Health England (PHE):…”