“…Brucellosis causes systemic symptoms, most often fever and malaise, and can involve many organs. Osteoarticular manifestations are frequent focal complications (Al Dahouk et al, 2007a). As observed in other Balkan countries, the male population accounted for most cases of brucellosis reported in Bosnia and Herzegovina (71 %) and infection resulted from occupational exposure (Obradović & Velić, 2010).…”
Section: Discussionmentioning
confidence: 96%
“…Accordingly, B. melitensis strains isolated in Germany are most often of the East Mediterranean genotype (Al Dahouk et al, 2007b). As was the case here, onset of symptoms often occurs after the end of the German summer holiday season (August/ September) and coincides with the return of immigrants from disease-endemic countries where the peak of human brucellosis cases is in June and July (Al Dahouk et al, 2007a).…”
Section: Discussionmentioning
confidence: 98%
“…The age group of 35-45 years accounted for 48 % of these cases (Obradović & Velić, 2010). In Germany, a country which was declared brucellosis-free in 2000, the epidemiology changed from a former occupational endemic infection to a travel-associated food-borne zoonosis, mainly affecting Turkish immigrants (Al Dahouk et al, 2007a). Since 2001, between 19 and 37 cases of brucellosis per year have been diagnosed in Germany.…”
Section: Discussionmentioning
confidence: 99%
“…This report underlines the proposal that immigrants from areas where brucellosis is endemic who present with infections of the skeletal system should undergo rapid diagnosis for brucellosis, a process which is often delayed (Al Dahouk et al, 2007a).…”
“…Brucellosis causes systemic symptoms, most often fever and malaise, and can involve many organs. Osteoarticular manifestations are frequent focal complications (Al Dahouk et al, 2007a). As observed in other Balkan countries, the male population accounted for most cases of brucellosis reported in Bosnia and Herzegovina (71 %) and infection resulted from occupational exposure (Obradović & Velić, 2010).…”
Section: Discussionmentioning
confidence: 96%
“…Accordingly, B. melitensis strains isolated in Germany are most often of the East Mediterranean genotype (Al Dahouk et al, 2007b). As was the case here, onset of symptoms often occurs after the end of the German summer holiday season (August/ September) and coincides with the return of immigrants from disease-endemic countries where the peak of human brucellosis cases is in June and July (Al Dahouk et al, 2007a).…”
Section: Discussionmentioning
confidence: 98%
“…The age group of 35-45 years accounted for 48 % of these cases (Obradović & Velić, 2010). In Germany, a country which was declared brucellosis-free in 2000, the epidemiology changed from a former occupational endemic infection to a travel-associated food-borne zoonosis, mainly affecting Turkish immigrants (Al Dahouk et al, 2007a). Since 2001, between 19 and 37 cases of brucellosis per year have been diagnosed in Germany.…”
Section: Discussionmentioning
confidence: 99%
“…This report underlines the proposal that immigrants from areas where brucellosis is endemic who present with infections of the skeletal system should undergo rapid diagnosis for brucellosis, a process which is often delayed (Al Dahouk et al, 2007a).…”
“…22 However, some studies have suggested a recent shift in the epidemiology of brucellosis from rural to urban settings, possibly related to unpasteurized milk consumption in urban environments. 39,40 A high Brucella seroprevalence among cattle in smallholder dairy systems in the Moshi area suggests that this sector may be a possible source of infection for the urban population. 18 With a larger sample size, an association between brucellosis and site of residence, socio-economic status, or tribe may have been observed.…”
Abstract. Acute and convalescent serum samples were collected from febrile inpatients identified at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive blood culture or a 4-fold increase in microagglutination test titer, and probable brucellosis was defined as a single reciprocal titer 160. Among 870 participants enrolled in the study, 455 (52.3%) had paired sera available. Of these, 16 (3.5%) met criteria for confirmed brucellosis. Of 830 participants with 1 serum sample, 4 (0.5%) met criteria for probable brucellosis. Brucellosis was associated with increased median age (P = 0.024), leukopenia (odds ratio [OR] 7.8, P = 0.005), thrombocytopenia (OR 3.9, P = 0.018), and evidence of other zoonoses (OR 3.2, P = 0.026). Brucellosis was never diagnosed clinically, and although all participants with brucellosis received antibacterials or antimalarials in the hospital, no participant received standard brucellosis treatment. Brucellosis is an underdiagnosed and untreated cause of febrile disease among hospitalized adult and pediatric patients in northern Tanzania.
BackgroundHuman brucellosis, otherwise known as undulant fever, is one of the most widespread zoonotic diseases in the world. Even though 9%–15% of stillbirths are known to be caused by infectious diseases, the study of the link between human Brucella melitensis and the termination of births in humans is a topic that has received little attention. This study examines if there was an association between infection of undulant fever, an endemic zoonotic disease in the Maltese Islands from 1919 until 1954, and reproductive loss through stillbirths.MethodsA univariate descriptive analysis was used to show the temporal trend of undulant fever time, as well as the age and sex distribution. Time series analysis was used to assess the relationship between time (months) and undulant fever cases with stillbirth proportions.ResultsOn the island of Gozo, the majority of undulant fever cases for both males and females occurred in their reproductive period between 15 and 45 years of age. Based on regression analysis, undulant fever had a statistically significant effect on the stillbirth rate for males (t = 2.8986, p = 0.0039). The effect of undulant fever on stillbirths was not significant for females (p = 0.9103).ConclusionThis paper highlights the importance of undulant fever as having implications for the health burden in pregnant women and potential fetal loss through stillbirths in the contemporary context.
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